Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw

Radiographic Findings in Patients with Medication-Related Osteonecrosis of the Jaw

A retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosi...

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Bibliographic Details
Published in:International Journal of Dentistry Vol. 2017; no. 2017; pp. 1 - 6-021
Main Authors: Curi, Marcos Martins, Santiago Júnior, Joel Ferreira, Franzolin, Solange de Oliveira Braga, Fernandes, Luciana Maria Paes da Silva Ramos, Curra, Cláudia, Barros, Carolina Arrabal, Cardoso, Camila Lopes, De Antoni, Carlos César
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Limiteds 01-01-2017
Hindawi Publishing Corporation
Hindawi
Hindawi Limited
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Summary:A retrospective study was conducted of the records and panoramic radiographs of 35 patients treated with bisphosphonates (BP) and diagnosed with MRONJ. Panoramic radiography was used for evaluation, by two examiners, the following findings were subject of search: osteolysis (OT), cortical bone erosion (EC), bone sclerosis focal (FS) and diffuse (DS), bone sequestration (BS), thickening of lamina dura (TD), prominence of the inferior alveolar nerve canal (IAN), persisting alveolar sockets (SK), and the presence of a pathological fracture (PF). Medical information and staging were also recorded in order to correlate with radiographic findings. Bone sclerosis was the most frequent alteration, followed by OT and TD. The mandible was more affected than the maxilla. There was no significant difference between genders or significant correlation between the number of injuries with age and duration of BP usage. Considering the association between the radiographic findings and MRONJ staging, EC was predominant in stage 3 and DS in stage 2. IAN and PF demonstrated greater association with stage 3. In conclusion, the higher the clinical staging, the greater the severity of the bone alteration. Panoramic radiographic examination is a useful screening tool in patients submitted to antiresorptive therapy.
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Academic Editor: Vincent Everts
ISSN:1687-8728
1687-8736
DOI:10.1155/2017/3190301