Search Results - "Barros, André L B"

In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy by Fernandes, Renata S, Arribada, Raquel Gregório, Silva, Juliana O, Silva-Cunha, Armando, Townsend, Danyelle M, Ferreira, Lucas A M, Barros, André L B

“…Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer patients. Despite its effectiveness, its inherent adverse toxic…”
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Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors by Tunes, Luiza G, Morato, Roberta E, Garcia, Adriana, Schmitz, Vinicius, Steindel, Mario, Corrêa-Junior, José D, Dos Santos, Hélio F, Frézard, Frédéric, de Almeida, Mauro V, Silva, Heveline, Moretti, Nilmar S, de Barros, André L. B, do Monte-Neto, Rubens L

“…The drugs currently used to treat leishmaniases have limitations concerning cost, efficacy, and safety, making the search for new therapeutic approaches…”
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Emetic Tartar-Loaded Liposomes as a New Strategy for Leishmaniasis Treatment by Coelho, Larissa D, Souza, Mirna M D, Cassali, Geovanni D, Silva, Raphaela A, Paiva, Maria J N, Barros, André L B, Teixeira, Eliane M, Silveira, Josianne N, Coelho, Paulo M Z, Aguiar, Marta M G, Oliveira, Mônica C

“…Emetic tartar (ET), was used in the treatment of leishmaniasis but its use was discontinued due to its low therapeutic index. Liposomes have been shown to be a…”
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Nanostructured Lipid Carrier Co-loaded with Doxorubicin and Docosahexaenoic Acid as a Theranostic Agent: Evaluation of Biodistribution and Antitumor Activity in Experimental Model by Fernandes, Renata S., Silva, Juliana O., Mussi, Samuel V., Lopes, Sávia C. A., Leite, Elaine A., Cassali, Geovanni D., Cardoso, Valbert N., Townsend, Danyelle M., Colletti, Patrick M., Ferreira, Lucas A. M., Rubello, Domenico, de Barros, André L. B.

“…Purpose Nanotheranostic platforms, i.e., the combination of both therapeutic and diagnostic agents on a single platform, are emerging as an interesting tool…”
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New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification by Munkert, Jennifer, Gomes, Eliza R, Marostica, Lucas L, Cota, Betânia B, Lopes, Cristina L. M, Andrade, Saulo F, Filho, José D. de Souza, Alves, Ricardo J, Oliveira, Monica C, Braga, Fernão C, Simões, Cláudia M. O, Pádua, Rodrigo M, de Barros, André L. B

“…In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown…”
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Current Applications of Plant-Based Drug Delivery Nano Systems for Leishmaniasis Treatment by dos Santos, Darline B, Lemos, Janaina A, Miranda, Sued E. M, Di Filippo, Leonardo D, Duarte, Jonatas L, Ferreira, Lucas A. M, Barros, Andre L. B, Oliveira, Anna E. M. F. M

“…Leishmania is a trypanosomatid that causes leishmaniasis. It is transmitted to vertebrate hosts during the blood meal of phlebotomine sandflies. The clinical…”
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Paclitaxel-loaded folate-coated long circulating and pH-sensitive liposomes as a potential drug delivery system: A biodistribution study by Monteiro, Liziane O.F., Fernandes, Renata S., Oda, Caroline M.R., Lopes, Sávia C., Townsend, Danyelle M., Cardoso, Valbert N., Oliveira, Mônica C., Leite, Elaine A., Rubello, Domenico, de Barros, André L.B.

“…A range of antitumor agents for cancer treatment is available; however, they show low specificity, which often limit their use. Recently, we have reported the…”
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Efficacy of nanoemulsion with Pterodon emarginatus Vogel oleoresin for topical treatment of cutaneous leishmaniasis by Kawakami, Monique Y.M., Zamora, Lisset Ortiz, Araújo, Raquel S., Fernandes, Caio P., Ricotta, Tiago Q.N., de Oliveira, Leandro G., Queiroz-Junior, Celso M., Fernandes, Ana Paula, da Conceição, Edemilson C., Ferreira, Lucas A.M., Barros, André L.B., Aguiar, Marta G., Oliveira, Anna E.M.F.M.

“…[Display omitted] •The Brazilian Sucupira tree oil has a wide range of biological properties.•SO-NE as a potential strategy for the cutaneous leishmaniasis…”
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Doxorubicin-loaded nanocarriers: A comparative study of liposome and nanostructured lipid carrier as alternatives for cancer therapy by Fernandes, Renata S, Silva, Juliana O, Monteiro, Liziane O.F, Leite, Elaine A, Cassali, Geovanni D, Rubello, Domenico, Cardoso, Valbert N, Ferreira, Lucas A.M, Oliveira, Mônica C, de Barros, André L.B

“…Abstract Nowadays cancer is one of the most common causes of deaths worldwide. Conventional antitumor agents still present various problems related to…”
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Technetium-99m-labeled doxorubicin as an imaging probe for murine breast tumor (4T1 cell line) identification by Fernandes, Renata S, Silva, Juliana de Oliveira, Lopes, Savia C.A, Chondrogiannis, Sotirios, Rubello, Domenico, Cardoso, Valbert N, Oliveira, Mônica C, Ferreira, Lucas A.M, de Barros, André L.B

“…OBJECTIVEEarly diagnosis of malignant tumors is essential to successfully plan a radical and curative approach. In this study we describe the direct…”
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Feasibility study with 99mTc-HYNIC-βAla-Bombesin(7–14) as an agent to early visualization of lung tumour cells in nude mice by Marostica, Lucas L, de Barros, André L.B, Silva, Juliana O, Lopes, Sávia C.A, Salgado, Breno S, Chondrogiannis, Sotirios, Rubello, Domenico, Cassali, Geovanni D, Schenkel, Eloir P, Cardoso, Valbert N, Simões, Cláudia M.O, Oliveira, Mônica C

“…AIMMore sensitive and accurate imaging approaches for early detection and therapy monitoring of lung tumours are needed to ameliorate prognosis and outcome…”
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Preliminary data of the antipancreatic tumor efficacy and toxicity of long-circulating and pH-sensitive liposomes containing cisplatin by Carlesso, Fernanda N, Araújo, Raquel S, Fuscaldi, Leonardo L, Mendes Miranda, Sued E, Rubello, Domenico, Teixeira, Cláudia S, dos Reis, Diego C, Leite, Elaine A, Silveira, Josianne N, Fernandes, Simone O.A, Cassali, Geovanni D, de Oliveira, Mônica C, Colletti, Patrick M, de Barros, André L.B, Cardoso, Valbert N

“…PURPOSEPancreatic cancer is the fourth most common cause of cancer-related death in the USA. This is mainly because of the chemoresistance of this type of…”
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New 99m Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification by Munkert, Jennifer, Gomes, Eliza R, Marostica, Lucas L, Cota, Betânia B, Lopes, Cristina L M, Andrade, Saulo F, Filho, José D de Souza, Alves, Ricardo J, Oliveira, Monica C, Braga, Fernão C, Simões, Cláudia M O, Pádua, Rodrigo M, de Barros, André L B

“…In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown…”
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Versican expression in canine carcinomas in benign mixed tumours: is there an association with clinical pathological factors, invasion and overall survival? by Damasceno, Karine A, Bertagnolli, Angélica C, Estrela-Lima, Alessandra, Ribeiro, Lorena Gr, Rabelo, Bruna S, Campos, Cecília B, Barros, André Lb, Cassali, Geovanni D

“…Components of the extracellular matrix have been studied in an attempt to elucidate the mechanisms involved in the biological behaviour of tumours. The…”
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Biomedical nanoparticle carriers with combined thermal and magnetic response: Current preclinical investigations by Tebaldi, Marli Luiza, Oda, Caroline M.R., Monteiro, Liziane O.F., de Barros, André L.B., Santos, Carla Junia, Soares, Daniel Cristian Ferreira

“…•SPIONs can be tailored with polymers combining temperature sensitivity and magnetic responses.•Dual sensitive nanoparticles represent a significant…”
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Permeability and in vivo distribution of poly(Ɛ-caprolactone) nanoparticles loaded with zidovudine by Magalhães, Milena C. R. S., Castro, Brenda F. M., de Castro, Whocely V., Barros, Andre L. B., Fernandes, Renata S., Silva-Cunha, Armando, Fialho, Sílvia L.

“…Zidovudine (AZT) is one of first choice drugs for the treatment of acquired immunodeficiency syndrome (AIDS). Despite its efficacy to control virus…”
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Hydroxyapatite nanoparticles: preparation, characterization, and evaluation of their potential use in bone targeting: an animal study by Maia, Ana Luiza C, Cavalcante, Carolina H, Souza, Marina G.F de, Ferreira, Carolina de A, Rubello, Domenico, Chondrogiannis, Sotirios, Cardoso, Valbert N, Ramaldes, Gilson A, Barros, André L.B de, Soares, Daniel C.F

“…OBJECTIVEHydroxyapatite is used as a drug-delivery system for bone therapy applications because of its biocompatibility, bioactivity, and osteoconductive…”
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α- Tocopherol succinate loaded nano-structed lipid carriers improves antitumor activity of doxorubicin in breast cancer models in vivo by Fernandes, Renata S., Silva, Juliana O., Seabra, Heloísa A., Oliveira, Mariana S., Carregal, Virgínia M., Vilela, José M.C., Andrade, Margareth S., Townsend, Danyelle M., Colletti, Patrick M., Leite, Elaine A., Cardoso, Valbert N., Ferreira, Lucas A.M., Rubello, Domenico, Barros, André L.B.

“…•Doxorubicin (DOX) and α-tocopheryl succinate (TS) loaded NLC was prepared.•The combination of DOX and TS at 1:4 ratio proved to be synergic in vitro.•The…”
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Technetium-99m radiolabeled paclitaxel as an imaging probe for breast cancer in vivo by Monteiro, Liziane O.F., Fernandes, Renata S., Castro, Luciano C., Cardoso, Valbert N., Oliveira, Mônica C., Townsend, Danyelle M., Ferretti, Alice, Rubello, Domenico, Leite, Elaine A., de Barros, André L.B.

“…The high incidence and mortality of breast cancer supports efforts to develop innovative imaging probes to effectively diagnose, evaluate the extent of the…”
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Evolving role of radiolabeled particles in detecting infection and inflammation, preliminary data with 99mTc-phytate in rats by Mota, Luciene G, de Barros, André L.B, Fuscaldi, Leonardo L, de Souza, Cristina M, Cassali, Geovanni D, Moghbel, Mateen, Alavi, Abass, Rubello, Domenico, Fernandes, Simone O.A, Oliveira, Mônica C, Cardoso, Valbert N

“…PURPOSEThe aim of this study was to evaluate the ability of phytate radiolabeled with technetium-99m (Tc-phytate) to identify inflammatory processes. MATERIALS…”
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