Search Results - "Barriere, David A."
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Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin
Published in Neuropharmacology (15-09-2018)“…Neurotoxicity remains the most common adverse effect of oxaliplatin, limiting its clinical use. In the present study, we developed a mouse model of chronic…”
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The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates Its Antiproliferative Activity in Mice
Published in International journal of molecular sciences (01-01-2022)“…Oxaliplatin, the first-line chemotherapeutic agent against colorectal cancer (CRC), induces peripheral neuropathies, which can lead to dose limitation and…”
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TRPV1 in brain is involved in acetaminophen-induced antinociception
Published in PloS one (17-09-2010)“…Acetaminophen, the major active metabolite of acetanilide in man, has become one of the most popular over-the-counter analgesic and antipyretic agents,…”
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Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Published in Pain (Amsterdam) (01-10-2022)“…Rheumatic diseases are often associated to debilitating chronic pain, which remains difficult to treat and requires new therapeutic strategies. We had…”
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A resting-state functional MR imaging and spectroscopy study of the dorsal hippocampus in the chronic unpredictable stress rat model
Published in The Journal of neuroscience (08-05-2019)“…Exposure to chronic stress leads to an array of anatomical, functional, and metabolic changes in the brain that play a key role in triggering psychiatric…”
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Fatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brain
Published in PloS one (05-08-2013)“…The discovery that paracetamol is metabolized to the potent TRPV1 activator N-(4-hydroxyphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide (AM404) and that this…”
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Paracetamol: a promising ancestor
Published in Therapie (01-07-2012)“…More than a century after its discovery, paracetamol remains the most widely used analgesic around the world. Despite elderly, its beneficial effects…”
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The development of brain magnetic resonance approaches in large animal models for preclinical research
Published in Animal frontiers (01-07-2019)“…Magnetic resonance imaging is a very powerful ap-proach to perform anatomical and functional imaging explorations. Large animal models are perfectly suited for…”
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Mammary cancer bone metastasis follow-up using multimodal small-animal MR and PET imaging
Published in Journal of Nuclear Medicine (01-06-2013)“…Despite tremendous progress in the management of breast cancer, the survival rate of this disease is still correlated with the development of metastases-most…”
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Lysophosphatidylcholine 16: 0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Published in Pain (Amsterdam) (27-01-2022)Get full text
Journal Article -
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TRPV.sub.1 in Brain Is Involved in Acetaminophen-Induced Antinociception
Published in PloS one (17-09-2010)“…Background Acetaminophen, the major active metabolite of acetanilide in man, has become one of the most popular over-the-counter analgesic and antipyretic…”
Get full text
Journal Article