Search Results - "Barrett, Cassandra"

Characterization of diverse homoserine lactone synthases in Escherichia coli by Daer, René, Barrett, Cassandra M, Melendez, Ernesto Luna, Wu, Jiaqi, Tekel, Stefan J, Xu, Jimmy, Dennison, Brady, Muller, Ryan, Haynes, Karmella A

“…Quorum sensing networks have been identified in over one hundred bacterial species to date. A subset of these networks regulate group behaviors, such as…”
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Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes by Barrett, Cassandra M, McCracken, Reilly, Elmer, Jacob, Haynes, Karmella A

“…A persistent challenge for mammalian cell engineering is the undesirable epigenetic silencing of transgenes. Foreign DNA can be incorporated into closed…”
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Genomic Answers for Kids: Toward more equitable access to genomic testing for rare diseases in rural populations by Cohen, Ana S.A., Berrios, Courtney D., Zion, Tricia N., Barrett, Cassandra M., Moore, Riley, Boillat, Emelia, Belden, Bradley, Farrow, Emily G., Thiffault, Isabelle, Zuccarelli, Britton D., Pastinen, Tomi

“…Next-generation sequencing has revolutionized the speed of rare disease (RD) diagnoses. While clinical exome and genome sequencing represent an effective tool…”
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Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty by Baldev, Khushboo, Dai, Feng, Barrett, Cassandra, Zhou, Bin, Shah, Misty, Howie, Benjamin, Boominathan, Praba, Zhao, Xuechun, Li, Jinlei

“…The use of glucocorticoid as local anesthetic adjuvant in single-injection adductor canal block (ACB) is well-documented but its effects in the presence of an…”
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Complex trait associations in rare diseases and impacts on Mendelian variant interpretation by Smail, Craig, Ge, Bing, Keever-Keigher, Marissa R., Schwendinger-Schreck, Carl, Cheung, Warren A., Johnston, Jeffrey J., Barrett, Cassandra, Feldman, Keith, Cohen, Ana S. A., Farrow, Emily G., Thiffault, Isabelle, Grundberg, Elin, Pastinen, Tomi

“…Emerging evidence implicates common genetic variation - aggregated into polygenic scores (PGS) - in the onset and phenotypic presentation of rare diseases…”
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Unlocking Access to DNA in Chromatin by Barrett, Cassandra M, Haynes, Karmella A

“…For decades, scientists have used DNA-binding enzymes derived from bacteria to artificially edit DNA sequences in eukaryotic hosts, including human cells…”
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Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity by Daer, René, Hamna, Fatima, Barrett, Cassandra M., Haynes, Karmella A.

“…Previously, we used an inducible, transgenic polycomb chromatin system to demonstrate that closed, transcriptionally silenced chromatin reduces Cas9 editing…”
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P868: How many lost diagnoses? Addressing inequitable access to genomic testing for rare diseases in rural populations by Cohen, Ana S.A., Barrett, Cassandra, Zion, Tricia, Moore, Riley, Boillat, Emelia, Belden, Bradley, Farrow, Emily, Thiffault, Isabelle, Berrios, Courtney, Zuccarelli, Britton, Pastinen, Tomi

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Downstream Exclusion in Rural Rare Disease Precision Medicine Research by Barrett, Cassandra, Berrios, Courtney

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853 Disseminating new clinical guidance during a pandemic by Cocks, Zoe, O’Connor, Margaret, Barrett, Cassandra, Kamarova, Halina

“…AimsEstablishing an innovative method of disseminating a new bronchiolitis guideline in a tertiary paediatric hospital.The ripple effect of the Covid-19…”
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OP315 - Developing role of genetic counselors in somatic gene therapy by Barrett, Cassandra, Dent, Karin, Spoth, Emily, Kaphingst, Kimberly

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Developing role of genetic counselors in somatic gene therapy by Barrett, Cassandra, Dent, Karin, Spoth, Emily, Kaphingst, Kimberly

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Design, Construction, and Validation of Histone-Binding Effectors in Vitro and in Cells by Tekel, Stefan J, Barrett, Cassandra, Vargas, Daniel, Haynes, Karmella A

“…Chromatin is a system of nuclear proteins and nucleic acids that plays a pivotal role in gene expression and cell behavior and is therefore the subject of…”
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Respiratory health and critical care concerns in Afghanistan by Shah, Jaffer, Essar, Mohammad Yasir, Qaderi, Shohra, Rackimuthu, Sudhan, Nawaz, Faisal A, Qaderi, Farah, Shah, Asghar

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Eat or heat: fuel poverty and childhood respiratory health by Barrett, Cassandra, Lee, Alice R, Abrams, Elissa M, Mayell, Sarah J, Hawcutt, Daniel B, Sinha, Ian P

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Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty by Khushboo Baldev, Feng Dai, Cassandra Barrett, Bin Zhou, Misty Shah, Benjamin Howie, Praba Boominathan, Xuechun Zhao, Jinlei Li

“…Introduction The use of glucocorticoid as local anesthetic adjuvant in single-injection adductor canal block (ACB) is well-documented but its effects in the…”
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Engineering Open Chromatin with Synthetic Pioneer Factors: Enhancing Mammalian Transgene Expression and Improving Cas9-Mediated Genome Editing in Closed Chromatin by Barrett, Cassandra M

“…Chromatin is the dynamic structure of proteins and nucleic acids into which eukaryotic genomes are organized. For those looking to engineer mammalian genomes,…”
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