Search Results - "Barreto Campello Carvalheira, José"
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Reduction of Hypothalamic Protein Tyrosine Phosphatase Improves Insulin and Leptin Resistance in Diet-Induced Obese Rats
Published in Endocrinology (Philadelphia) (01-08-2008)“…Protein tyrosine phosphatase (PTP1B) has been implicated in the negative regulation of insulin and leptin signaling. PTP1B knockout mice are hypersensitive to…”
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2
Abdominal adiposity as a prognosis biomarker of clinical outcome in metastatic colorectal cancer
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2023)“…[Display omitted] •Higher subcutaneous and visceral adipose tissue radiodensity is associated with greater risk for death in patients with metastatic…”
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3
Examining variations in body composition among patients with colorectal cancer according to site and disease stage
Published in Scientific reports (11-05-2024)“…Patients with colorectal cancer (CRC) often exhibit changes in body composition (BC) which are associated with poorer clinical outcomes. Many studies group…”
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4
Impact of androgen deprivation therapy on mortality of prostate cancer patients with COVID-19: a propensity score-based analysis
Published in Infectious agents and cancer (25-11-2021)“…Background Previous studies hypothesized that androgen deprivation therapy (ADT) may reduce severe acute respiratory syndrome coronavirus 2 (SARS-COV2)…”
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5
Myosteatosis Differentially Affects the Prognosis of Non-Metastatic Colon and Rectal Cancer Patients: An Exploratory Study
Published in Frontiers in oncology (11-11-2021)“…Body composition performed by computed tomography (CT) impacts on cancer patients’ prognoses and responses to treatment. Myosteatosis has been related to…”
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6
Assessing the role of prognostic nutritional index in predicting outcomes for rectal cancer surgery
Published in Clinical nutrition ESPEN (01-10-2024)“…The association of Prognostic Nutritional Index (PNI) with prognosis has been established for various cancer types, including rectal cancer. However, the…”
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7
Metabolic Volume Measurements in Multiple Myeloma
Published in Metabolites (16-12-2021)“…Multiple myeloma (MM) accounts for 10-15% of all hematologic malignancies, as well as 20% of deaths related to hematologic malignant tumors, predominantly…”
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Adipose tissue radiodensity: A new prognostic biomarker in people with multiple myeloma
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-06-2021)“…•Higher subcutaneous adipose tissue radiodensity is associated with reduced subcutaneous and visceral adipose tissue as well as reduced leptin levels.•Higher…”
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Repurposing metformin for the treatment of gastrointestinal cancer
Published in World journal of gastroenterology : WJG (07-05-2021)“…Diabetes mellitus type 2 and cancer share many risk factors. The pleiotropic insulin-dependent and insulin-independent effects of metformin might inhibit…”
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10
Blood spotlight on leukocytes and obesity
Published in Blood (07-11-2013)“…The rise of obesity and its attendant pathological sequelae, including type 2 diabetes and coronary artery disease, constitute an ongoing public health…”
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Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial
Published in British journal of cancer (16-03-2021)“…Background Patients with refractory colorectal (CRC) cancer have few treatment options. This trial tests the combination of metformin and irinotecan in this…”
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DEEP LEARNING FOR CT IMAGES SEGMENTATION
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: Computed tomography (CT) scans are integral to cancer patient diagnosis, revealing changes in body composition linked to survival…”
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13
iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents
Published in Scientific reports (23-08-2017)“…Inducible nitric oxide (iNOS)-mediated S-nitrosation of the metabolic signaling pathway has emerged as a post-translational modification that triggers insulin…”
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14
PROGNOSTIC EVALUATION OF THE NUTRITIONAL PROGNOSTIC INDEX IN PATIENTS WITH NON-METASTATIC RECTAL CANCER
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: Rectal cancer (RC) is one of the leading causes of cancer mortality worldwide. Recent studies indicate that systemic inflammation…”
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15
Association of Fibrinolytic Potential and Risk of Mortality in Cancer Patients
Published in Cancers (01-09-2023)“…Cancer is a leading cause of death, and the fibrinolytic system shows cooperative effects that facilitate the growth of tumors and the appearance of…”
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Obesity as a Possible Risk Factor for Progression from Monoclonal Gammopathy of Undetermined Significance Progression into Multiple Myeloma: Could Myeloma Be Prevented with Metformin Treatment?
Published in Advances in hematology (2021)“…Obesity is increasingly associated with the transformation of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma (MM). Obesity,…”
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17
Metformin and blood cancers
Published in Clinics (São Paulo, Brazil) (01-01-2018)“…Type 2 diabetes mellitus and cancer are correlated with changes in insulin signaling, a pathway that is frequently upregulated in neoplastic tissue but…”
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LOW MUSCULARITY IMPACTS SURVIVAL IN PATIENTS WITH METASTATIC OR RECURRENT HEAD AND NECK CANCER
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: The prognosis of patients with head and neck cancer (HNC) is determined by factors extrinsic and intrinsic to the patient and the…”
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ASSOCIATION BETWEEN BODY COMPOSITION AND SURVIVAL IN LOCALLY ADVANCED HEAD AND NECK CANCER TREATED WITH RADIOTHERAPY
Published in Hematology, Transfusion and Cell Therapy (01-04-2024)“…Introduction/Justification: Malnutrition is a frequent condition in patients with head and neck cancer (HNC) due to the location of the tumor, treatment, and…”
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Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia
Published in Blood advances (28-09-2021)“…Insulin and insulin-like growth factors (IGFs) are mitogenic and prosurvival factors to many different cell types, including acute lymphoblastic leukemia…”
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