Search Results - "Barresi, A"
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Prediction of Ice Crystal Size Distribution after Freezing of Pharmaceutical Solutions
Published in Crystal growth & design (06-09-2017)“…In the pharmaceutical industry, much attention has been given to the problem of predicting the average size of solvent crystals formed during freezing of…”
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Advanced approach to build the design space for the primary drying of a pharmaceutical freeze-drying process
Published in Journal of pharmaceutical sciences (01-11-2011)“…This paper deals with the design space of a pharmaceutical freeze-drying process. Mathematical modeling is used to investigate the effect of the operating…”
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3
On the use of mathematical models to build the design space for the primary drying phase of a pharmaceutical lyophilization process
Published in Journal of pharmaceutical sciences (01-01-2011)“…The aim of this article is to show a procedure to build the design space for the primary drying of a pharmaceuticals lyophilization process. Mathematical…”
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4
Measuring and predicting pore size distribution of freeze-dried solutions
Published in Drying technology (12-03-2019)“…In this work, a novel procedure is presented for the measurement and prediction of pore size distribution of freeze-dried solutions in vials. A method based on…”
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5
Overcoming the Limits of Flash Nanoprecipitation: Effective Loading of Hydrophilic Drug into Polymeric Nanoparticles with Controlled Structure
Published in Polymers (02-10-2018)“…Flash nanoprecipitation (FNP) is a widely used technique to prepare particulate carriers based on various polymers, and it was proven to be a promising…”
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Nanoprecipitation in confined impinging jets mixers: Production, characterization and scale-up of pegylated nanospheres and nanocapsules for pharmaceutical use
Published in Chemical engineering science (30-07-2012)“…This work focuses on the investigation of the mechanisms of nanoparticles formation, through nanoprecipitation in micromixers. Polymer nanoparticles (including…”
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The Polluter Pays Principle as an Instrument of Municipal and Global Environmental Governance in Climate Change Mitigation Law: Lessons from China, India, and the United States
Published in Climate law (01-03-2020)“…The disparate fates of the polluter pays principle (ppp) as an instrument of municipal environmental governance in the environmental law of China, India, and…”
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Improving radioactive contaminant identification through the analysis of delayed coincidences with an α-spectrometer
Published in The European physical journal. C, Particles and fields (01-11-2021)“…In the framework of rare event searches, the identification of radioactive contaminants in ultra-pure samples is a challenging task, because the signal is…”
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On the Use of Temperature Measurements as a Process Analytical Technology (PAT) for the Monitoring of a Pharmaceutical Freeze-Drying Process
Published in Pharmaceutics (01-03-2023)“…The measurement of product temperature is one of the methods that can be adopted, especially in the pharmaceutical industry, to monitor the freeze-drying…”
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Design and scale-up of chemical reactors for nanoparticle precipitation
Published in AIChE journal (01-05-2006)“…In recent years there has been a growing interest in production on an industrial scale of particles with size in the sub‐micron range (40‐200 nm). This can be…”
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Quality by design: optimization of a freeze-drying cycle via design space in case of heterogeneous drying behavior and influence of the freezing protocol
Published in Pharmaceutical development and technology (01-02-2013)“…Purpose: This paper shows how to optimize the primary drying phase, for both product quality and drying time, of a parenteral formulation via design space…”
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On the robustness of the soft sensors used to monitor a vial freeze-drying process
Published in Drying technology (04-07-2017)“…Process monitoring is a key issue in pharmaceutical freeze-drying to evaluate if the limit product temperature is approached, to identify the ending point of…”
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13
Model validation for precipitation in solvent-displacement processes
Published in Chemical engineering science (24-12-2012)“…In this work a model for precipitation of polymer nanoparticles in solvent-displacement processes is presented and validated. The model is based on…”
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Freeze-Drying of Pharmaceuticals in Vials Nested in a Rack System-Part I: Freezing Behaviour
Published in Pharmaceutics (01-02-2023)“…The distribution of biopharmaceuticals often requires either ultra-cold conditions or lyophilisation. In both cases, the drug product is frozen and, thus,…”
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The Freeze-Drying of Pharmaceuticals in Vials Nested in a Rack System—Part II: Primary Drying Behaviour
Published in Pharmaceutics (01-11-2023)“…The freeze-drying of biopharmaceuticals is a common strategy to extend their shelf-life and facilitate the distribution of therapeutics. The drying phase is…”
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Quadrature method of moments for population-balance equations
Published in AIChE journal (01-05-2003)“…Although use of computational fluid dynamics (CFD) for simulating precipitation (and particulate systems in general) is becoming a standard approach, a number…”
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Bio-Functional Textiles: Combining Pharmaceutical Nanocarriers with Fibrous Materials for Innovative Dermatological Therapies
Published in Pharmaceutics (11-08-2019)“…In the field of pharmaceutical technology, significant attention has been paid on exploiting skin as a drug administration route. Considering the structural…”
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Journal Article -
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NaTech triggered by lightning: Novel insights from past events in the process industry
Published in Heliyon (15-06-2024)“…Lightning strikes, a prominent meteorological event, pose a significant risk of triggering technological disruptions within the process industry. To better…”
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Quality by Design: Scale-Up of Freeze-Drying Cycles in Pharmaceutical Industry
Published in AAPS PharmSciTech (01-09-2013)“…This paper shows the application of mathematical modeling to scale-up a cycle developed with lab-scale equipment on two different production units. The above…”
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Functionalization of Cotton Fabrics with Polycaprolactone Nanoparticles for Transdermal Release of Melatonin
Published in Journal of functional biomaterials (24-12-2017)“…Drug delivery by means of transdermal patches raised great interest as a non-invasive and sustained therapy. The present research aimed to design a patch for…”
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