Search Results - "Barrese, V."
-
1
KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus
Published in Pharmacological research (01-10-2011)“…Voltage-dependent type 7 K+ (KV7) channels play important physiological roles in neurons and muscle cells. The aims of the present study were to investigate…”
Get full text
Journal Article -
2
Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus
Published in European journal of pain (01-09-2012)“…Background Gamma‐aminobutyric acid (GABA) and glutamate (GLU) are involved in nociceptive signals processing in the trigeminal system. In this study, we…”
Get full text
Journal Article -
3
Tailoring therapy for heart failure: the pharmacogenomics of adrenergic receptor signaling
Published in Pharmacogenomics and personalized medicine (01-01-2014)“…Heart failure is one of the leading causes of mortality in Western countries, and β-blockers are a cornerstone of its treatment. However, the response to these…”
Get full text
Journal Article -
4
KCNQ-Encoded Potassium Channels as Therapeutic Targets
Published in Annual review of pharmacology and toxicology (06-01-2018)“…K v 7 channels are voltage-gated potassium channels encoded by KCNQ genes that have a considerable physiological impact in many cell types. This reliance upon…”
Get full text
Journal Article -
5
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2022)“…Developmental and epileptic encephalopathies (DEEs) are neurodevelopmental diseases characterized by refractory epilepsy, distinct electroencephalographic and…”
Get full text
Journal Article -
6
K V7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus
Published in Pharmacological research (2011)“…Voltage-dependent type 7 K + (K V7) channels play important physiological roles in neurons and muscle cells. The aims of the present study were to investigate…”
Get full text
Journal Article -
7
Molecular and pharmacological evidence for a facilitatory functional role of pre‐synaptic GLUK 2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus
Published in European journal of pain (01-09-2012)“…Abstract Background Gamma‐aminobutyric acid ( GABA ) and glutamate ( GLU ) are involved in nociceptive signals processing in the trigeminal system. In this…”
Get full text
Journal Article -
8
Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine
Published in Clinical pharmacology: advances and applications (01-01-2010)“…Despite the availability of over 20 antiepileptic drugs, about 30% of epileptic patients do not achieve seizure control. Thus, identification of additional…”
Get full text
Journal Article -
9
Decreased Subunit Stability as a Novel Mechanism for Potassium Current Impairment by a KCNQ2 C Terminus Mutation Causing Benign Familial Neonatal Convulsions
Published in The Journal of biological chemistry (06-01-2006)“…KCNQ2 and KCNQ3 K+ channel subunits underlie the muscarinic-regulated K+ current (IKM), a widespread regulator of neuronal excitability. Mutations in KCNQ2- or…”
Get full text
Journal Article -
10
Erratum
Published in Clinical pharmacology: advances and applications (01-03-2012)Get full text
Journal Article