Search Results - "Barrero, Carlos"

Multi-Omics Analysis Identified Drug Repurposing Targets for Chronic Obstructive Pulmonary Disease by Wang, Fang, Barrero, Carlos A

“…Despite recent advances in chronic obstructive pulmonary disease (COPD) research, few studies have identified the potential therapeutic targets systematically…”
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer by Zhang, Hanghang, Pandey, Somnath, Travers, Meghan, Sun, Hongxing, Morton, George, Madzo, Jozef, Chung, Woonbok, Khowsathit, Jittasak, Perez-Leal, Oscar, Barrero, Carlos A., Merali, Carmen, Okamoto, Yasuyuki, Sato, Takahiro, Pan, Joshua, Garriga, Judit, Bhanu, Natarajan V., Simithy, Johayra, Patel, Bela, Huang, Jian, Raynal, Noël J.-M., Garcia, Benjamin A., Jacobson, Marlene A., Kadoch, Cigall, Merali, Salim, Zhang, Yi, Childers, Wayne, Abou-Gharbia, Magid, Karanicolas, John, Baylin, Stephen B., Zahnow, Cynthia A., Jelinek, Jaroslav, Graña, Xavier, Issa, Jean-Pierre J.

“…Cyclin-dependent kinase 9 (CDK9) promotes transcriptional elongation through RNAPII pause release. We now report that CDK9 is also essential for maintaining…”
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Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men by Boden, Guenther, Homko, Carol, Barrero, Carlos A, Stein, T Peter, Chen, Xinhua, Cheung, Peter, Fecchio, Chiara, Koller, Sarah, Merali, Salim

“…Obesity-linked insulin resistance greatly increases the risk for type 2 diabetes, hypertension, dyslipidemia, and non-alcoholic fatty liver disease, together…”
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Task Shifting and Task Sharing to Strengthen the Surgical Workforce in Sub-Saharan Africa: A Systematic Review of the Existing Literature by Ryan, Isabel, Shah, Keshav V., Barrero, Carlos E., Uamunovandu, Tjinjeka, Ilbawi, Andre, Swanson, Jordan

“…Background A major constraint to surgical care delivery in low-resource settings is inadequate workforce availability. Surgical task shifting (TShifting) and…”
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HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis by Barrero, Carlos A, Datta, Prasun K, Sen, Satarupa, Deshmane, Satish, Amini, Shohreh, Khalili, Kamel, Merali, Salim

“…Human immunodeficiency virus type 1 encoded viral protein Vpr is essential for infection of macrophages by HIV-1. Furthermore, these macrophages are resistant…”
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Understanding Breast Cancer Aggressiveness and Its Implications in Diagnosis and Treatment by Afifi, Nader, Barrero, Carlos A

“…Breast cancer (BC) is the most common form of cancer in women worldwide [...]…”
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Sustained caloric restriction potentiates insulin action by activating prostacyclin synthase by Merali, Carmen, Quinn, Connor, Huffman, Kim M, Pieper, Carl F, Bogan, Jonathan S, Barrero, Carlos A, Merali, Salim

“…Caloric restriction (CR) is known to enhance insulin sensitivity and reduce the risk of metabolic disorders; however, its molecular mechanisms are not fully…”
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Glutamate metabolism in HIV-1 infected macrophages: Role of HIV-1 Vpr by Datta, Prasun K, Deshmane, Satish, Khalili, Kamel, Merali, Salim, Gordon, John C, Fecchio, Chiara, Barrero, Carlos A

“…HIV-1 infected macrophages play a significant role in the neuropathogenesis of AIDS. HIV-1 viral protein R (Vpr) not only facilitates HIV-1 infection but also…”
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Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction-associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells by Quinn, Connor, Rico, Mario C, Merali, Carmen, Barrero, Carlos A, Perez-Leal, Oscar, Mischley, Victoria, Karanicolas, John, Friedman, Scott L, Merali, Salim

“…Hepatic fibrosis is the primary determinant of mortality in patients with metabolic dysfunction-associated steatohepatitis (MASH). Transforming growth factor-β…”
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Predisposing Factors for Postoperative Complications in the Year Following Fronto-Orbital Advancement and Remodeling: A Single Institution Study of 267 Patients by Wietlisbach, Larissa E, Barrero, Carlos E, Villavisanis, Dillan F, Swanson, Jordan W, Bartlett, Scott P, Taylor, Jesse A

“…Fronto-orbital advancement and remodeling (FOAR) is a common surgical approach used for craniosynostosis conferring functional and aesthetic benefit. There are…”
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Associations Between Medicaid Expansion and Timely Repair of Cleft Lip and Palate by Barrero, Carlos E., Kavanagh, Nolan M., Pontell, Matthew E., Salinero, Lauren K., Wagner, Connor S., Bartlett, Scott P., Taylor, Jesse A., Swanson, Jordan W.

“…The expansion of Medicaid under the Affordable Care Act (ACA) increased access to health care for many low-income children. However, the impact of this…”
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Development of enhanced ethanol ablation as an alternative to surgery in treatment of superficial solid tumors by Morhard, Robert, Nief, Corrine, Barrero Castedo, Carlos, Hu, Fangyao, Madonna, Megan, Mueller, Jenna L., Dewhirst, Mark W., Katz, David F., Ramanujam, Nirmala

“…While surgery is at the foundation of cancer treatment, its access is limited in low-income countries. Here, we describe development of a low-cost alternative…”
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Identification of Inhibitors of Tubulin Polymerization Using a CRISPR-Edited Cell Line with Endogenous Fluorescent Tagging of β-Tubulin and Histone H1 by Khachatryan, Harutyun, Olszowy, Bartlomiej, Barrero, Carlos A, Gordon, John, Perez-Leal, Oscar

“…Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating cell division. Inhibiting tubulin polymerization has been…”
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Speech Outcomes and Rates of Secondary Speech Surgery from Childhood to Skeletal Maturity following Modified Furlow Palatoplasty by Salinero, Lauren K, Wagner, Connor S, Barrero, Carlos E, Valenzuela, Zachary D, McCormack, Susan M, Solot, Cynthia, Cohen, Marilyn, Kirschner, Richard E, Low, David W, Jackson, Oksana A

“…This study updates the authors' institutional experience with modified Furlow palatoplasty, evaluating speech outcomes and incidence of secondary speech…”
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How Does CLEFT-Q Change the Way We Practice? A Prospective Study Integrating Patient-Reported Outcomes by Salinero, Lauren K, Cheung, Liana, Villavisanis, Dillan F, Wagner, Connor S, Barrero, Carlos E, Pontell, Matthew E, Jackson, Oksana A, Taylor, Jesse A, Low, David W, Swanson, Jordan W

“…The CLEFT-Q is a validated instrument designed to elicit patient-reported outcomes among people affected by cleft lip and/or palate. However, it has not been…”
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Radiographic Evidence of Dental Complications after Mandibular Distraction Osteogenesis: Inverted-L versus Oblique Osteotomy by Barrero, Carlos E, Ryan, Isabel A, Salinero, Lauren, McGraw, J Reed, Pontell, Matthew E, Bartlett, Scott P, Napoli, Joseph A, Swanson, Jordan W, Nah, Hyun-Duck, Taylor, Jesse A

“…Patients with micrognathia undergoing mandibular distraction osteogenesis (MDO) for functional and aesthetic improvement are at significant risk for dental…”
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Long-Term Outcomes and Growth Analysis of Costochondral Grafts for Hemifacial Microsomia: 24-Year Experience of a Single Surgeon by Barrero, Carlos E, Villavisanis, Dillan F, Wietlisbach, Larissa E, Pontell, Matthew E, Wagner, Connor S, Salinero, Lauren K, Swanson, Jordan W, Taylor, Jesse A, Nah, Hyun-Duck, Bartlett, Scott P

“…Costochondral grafts (CCGs) can be used in mandibular reconstruction of Kaban-Pruzansky IIB/III hemifacial microsomia (HFM). Their growth is variable,…”
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Genetic Subtypes of Apert Syndrome Are Associated With Differences in Airway Morphology and Early Upper Airway Obstruction by Wagner, Connor S., Wietlisbach, Larissa E., Kota, Anchith, Villavisanis, Dillan F., Pontell, Matthew E., Barrero, Carlos E., Salinero, Lauren K., Swanson, Jordan W., Taylor, Jesse A., Bartlett, Scott P.

“…Background: Apert syndrome is predominantly caused by 2 paternally inherited gain-of-function mutations in the FGFR2 gene, Pro253Arg, and Ser252Trp. Studies…”
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Kaban-Pruzansky Grade Predicts Airway Severity in Hemifacial Microsomia by Barrero, Carlos E, Pontell, Matthew E, Ryan, Isabel A, Wietlisbach, Larissa E, Wagner, Connor S, Salinero, Lauren, Swanson, Jordan W, Liao, Eric C, Bartlett, Scott P, Taylor, Jesse A

“…Children born with hemifacial microsomia (HFM) can experience airway compromise. There is a paucity of data correlating degree of HFM severity with airway…”
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Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IRA Signal in Malignant Mesothelioma by Scalia, Pierluigi, Merali, Carmen, Barrero, Carlos, Suma, Antonio, Carnevale, Vincenzo, Merali, Salim, Williams, Stephen J.

“…EphB4 angiogenic kinase over-expression in Mesothelioma cells relies upon a degradation rescue signal provided by autocrine IGF-II activation of Insulin…”
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