Search Results - "Barreiros, Luisa"
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Automatic and renewable micro-solid-phase extraction based on bead injection lab-on-valve system for determination of tranexamic acid in urine by UHPLC coupled with tandem mass spectrometry
Published in Analytical and bioanalytical chemistry (2022)“…An automatic micro-solid-phase extraction (μSPE) method using on-line renewable sorbent beads followed by liquid chromatography–tandem mass spectrometry…”
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Insights on Ultrafiltration-Based Separation for the Purification and Quantification of Methotrexate in Nanocarriers
Published in Molecules (Basel, Switzerland) (18-04-2020)“…The evaluation of encapsulation efficiency is a regulatory requirement for the characterization of drug delivery systems. However, the difficulties in…”
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Determination of neuropeptide Y Y1 receptor antagonist BIBP 3226 and evaluation of receptor expression based on liquid chromatography coupled with tandem mass spectrometry
Published in Analytical and bioanalytical chemistry (01-09-2020)“…Neuropeptide Y (NPY) is a peptide widely distributed throughout the body that is involved in various physiological processes, including the regulation of…”
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Benefits of fermented papaya in human health
Published in Foods (16-02-2022)“…Fermented foods have been used for several years all over the world, due to their unique nutritional characteristics and because fermentation promotes…”
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Olive oil waste as a source of functional food ingredients: Assessing polyphenolic content and antioxidant activity in olive leaves
Published in Foods (01-01-2024)“…Around two million tons of olive oil are produced in Europe annually, with Portugal being among the top five European olive oil-producing countries. Olive oil…”
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Assessing the differences of two vineyards soils’ by NIR spectroscopy and chemometrics
Published in Heliyon (01-12-2023)“…Soil properties influence greatly the status of vine plants which consequently influences the quality of wine. Therefore, in the context of viticulture…”
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Exploiting kinetic features of ORAC assay for evaluation of radical scavenging capacity
Published in Antioxidants (17-02-2023)“…The analysis and interpretation of data retrieved from Oxygen Radical Absorbance Capacity (ORAC) assays represent a challenging task. ORAC indexes originate…”
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Screening of Antioxidant Effect of Spontaneous and Bioinoculated with Gluconobacter oxydans Fermented Papaya: A Comparative Study
Published in Fermentation (Basel) (01-02-2023)“…Fermented papaya is recognized as a nutraceutical with a diverse and rich composition. Fermentation of fruit with desirable microorganisms could be a strategy…”
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Micro-bead injection spectroscopy for label-free automated determination of immunoglobulin G in human serum
Published in Analytical and bioanalytical chemistry (01-01-2018)“…Immunoglobulin G (IgG) represents the major fraction of antibodies in healthy adult human serum, and deviations from physiological levels are a generic marker…”
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Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS
Published in Pharmaceuticals (Basel, Switzerland) (23-11-2021)“…The quantitative analysis of pharmaceuticals in biomatrices by liquid chromatography coupled with electrospray ionization tandem mass spectrometry…”
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Development of a Screening Method for Sulfamethoxazole in Environmental Water by Digital Colorimetry Using a Mobile Device
Published in Chemosensors (01-01-2022)“…Antibiotic resistance is a major health concern of the 21st century. The misuse of antibiotics over the years has led to their increasing presence in the…”
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Human Platelet Antigens in Brazilian Multiethnic Populations: Occurrence of Regional Variation and Frequency in a Large Urban Center (Belo Horizonte)
Published in Transfusion medicine and hemotherapy (01-11-2018)“…Background: The frequency of human platelet antigens (HPA) varies according to ethnicity, which causes differences in the morbidity of alloimmune and…”
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Characterization of phospholipid vesicles containing lauric acid: physicochemical basis for process and product development
Published in Heliyon (01-10-2019)“…Lauric acid (LAH) strongly inhibits the growth of acne-causing bacteria. LAH is essentially water-insoluble and the solubility of laurate (LA) salts are medium…”
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Miniaturized Fluorimetric Method for Quantification of Zinc in Dry Dog Food
Published in Journal of analytical methods in chemistry (2020)“…Zinc is an essential trace element for animals in several biological processes, particularly in energy production, and it is acquired from food ingestion. In…”
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Valorization of grape pomace: Extraction of bioactive phenolics with antioxidant properties
Published in Industrial crops and products (15-11-2015)“…•Grape pomace from Portuguese cultivars was targeted as source of polyphenolic compounds.•An environmental-friendly extract with polyphenols was…”
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Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs
Published in Journal of controlled release (10-12-2016)“…Combining two or more antiretroviral drugs in one medical product is an interesting but challenging strategy for developing topical anti-HIV microbicides. We…”
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Topical co-delivery of methotrexate and etanercept using lipid nanoparticles: A targeted approach for psoriasis management
Published in Colloids and surfaces, B, Biointerfaces (01-11-2017)“…[Display omitted] •Cetyl palmitate SLNs with MTX and functionalized with etanercept were synthesized.•Enhanced skin deposition of MTX when incorporated within…”
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Methotrexate loaded lipid nanoparticles for topical management of skin-related diseases: Design, characterization and skin permeation potential
Published in International journal of pharmaceutics (15-10-2016)“…[Display omitted] •Nanostructured lipid carriers composed of Cetyl palmitate and Miglyol were used to deliver methotrexate.•Methotrexate exhibited an in vitro…”
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Noncovalent PEG Coating of Nanoparticle Drug Carriers Improves the Local Pharmacokinetics of Rectal Anti-HIV Microbicides
Published in ACS applied materials & interfaces (17-10-2018)“…Antiretroviral drug nanocarriers hold great promise for developing anti-human immunodeficiency virus (HIV) rectal microbicides. However, challenges remain,…”
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Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms
Published in Acta biomaterialia (15-04-2017)“…Transport pathways of NLCs across human epidermal epithelial monolayer. [Display omitted] Knowledge of delivery system transport through epidermal cell…”
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