Search Results - "Barreira, Fabiana"

The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform by Maguire, Brittany J, Dahal, Prabin, Rashan, Sumayyah, Ngu, Roland, Boon, Anca, Forsyth, Colin, Strub-Wourgraft, Nathalie, Chatelain, Eric, Barreira, Fabiana, Sosa-Estani, Sergio, Guérin, Philippe J

“…Background Chagas disease (CD), caused by the parasite Trypanosoma cruzi , affects ~6–7 million people worldwide. Significant limitations still exist in our…”
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Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: A systematic review and meta-analysis by Ciapponi, Agustín, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascón, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino, Ribeiro, Isabela, Villar, Juan Carlos, Sosa-Estani, Sergio

“…Chagas disease is a neglected disease that remains a public health threat, particularly in Latin America. The most important treatment options are…”
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Clinical use of molecular methods for Trypanosoma cruzi infection in endemic and non-endemic countries: Benefits, limitations and challenges by Pinazo, Maria-Jesus, Forsyth, Colin J., Lopez-Albizu, Constanza, Bisio, Margarita María Catalina, González-Martínez, Adriana, Bohorquez, Laura, Pinto, Jimy, Molina, Israel, Marchiol, Andrea, Herazo, Rafael, Galván, Irene Losada, Marques, Tayná, Barreira, Fabiana, Villar, Juan Carlos, Sguassero, Yanina, Santini, Maria Soledad, Altcheh, Jaime, Alarcón de Noya, Belkisyolé, Sosa-Estani, Sergio

“…Trypanosoma cruzi infection is diagnosed by parasitological, molecular, and serological tests. Molecular methods based on DNA amplification provide a more…”
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A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease by Torrico, Faustino, Gascón, Joaquim, Ortiz, Lourdes, Pinto, Jimy, Rojas, Gimena, Palacios, Alejandro, Barreira, Fabiana, Blum, Bethania, Schijman, Alejandro Gabriel, Vaillant, Michel, Strub-Wourgaft, Nathalie, Pinazo, Maria-Jesus, Bilbe, Graeme, Ribeiro, Isabela

“…Chagas disease (CD) has significant global health impact, but safe, effective treatments remain elusive. The nitroimidazole fexinidazole is a potential…”
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Benznidazole in Chagas disease study: do the data justify progression to phase 3? – Authors’ reply by Torrico, Faustino, Barreira, Fabiana, Strub-Wourgaft, Nathalie, Ribeiro, Isabella, Sosa-Estani, Sergio

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New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial by Torrico, Faustino, Gascón, Joaquim, Barreira, Fabiana, Blum, Bethania, Almeida, Igor C, Alonso-Vega, Cristina, Barboza, Tayná, Bilbe, Graeme, Correia, Erika, Garcia, Wilson, Ortiz, Lourdes, Parrado, Rudy, Ramirez, Juan Carlos, Ribeiro, Isabela, Strub-Wourgaft, Nathalie, Vaillant, Michel, Sosa-Estani, Sergio, Arteaga, Roger, de la Barra, Anabelle, Camacho Borja, Jhonny, Martinez, Ivana, Fernandes, Jayme, Garcia, Lineth, Lozano, Daniel, Palacios, Alejandro, Schijman, Alejandro, Pinazo, Maria Jesus, Pinto, Jimmy, Rojas, Gimena, Estevao, Igor, Ortega-Rodriguez, Uriel, Mendes, Maria Tays, Schuck, Edgar, Hata, Katsura, Maki, Noritsugu, Asada, Makoto

“…Current treatment for Chagas disease with the only available drugs, benznidazole or nifurtimox, has substantial limitations, including long treatment duration…”
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Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America by Alonso-Padilla, Julio, Cortés-Serra, Nuria, Pinazo, María Jesús, Bottazzi, María Elena, Abril, Marcelo, Barreira, Fabiana, Sosa-Estani, Sergio, Hotez, Peter Jay, Gascón, Joaquim

“…Chagas disease, caused by infection with the parasite Trypanosoma cruzi, represents a huge public health problem in the Americas, where millions of people are…”
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Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial by Pinazo, Maria-Jesus, Forsyth, Colin, Losada, Irene, Esteban, Elena Trigo, García-Rodríguez, Magdalena, Villegas, Maria Luz, Molina, Israel, Crespillo-Andújar, Clara, Gállego, Montserrat, Ballart, Cristina, Ramirez, Juan Carlos, Aden, Tilman, Hoerauf, Achim, Pfarr, Kenneth, Vaillant, Michel, Marques, Tayná, Fernandes, Jayme, Blum, Bethania, Ribeiro, Isabela, Sosa-Estani, Sergio, Barreira, Fabiana, Gascón, Joaquim

“…More than six million people worldwide, particularly in vulnerable communities in Latin America, are infected with Trypanosoma cruzi, the causative agent of…”
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Direct evidence gap on fixed versus adjusted‐dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: Systematic review and individual patient data meta‐analysis by Ciapponi, Agustín, Barreira, Fabiana, Perelli, Lucas, Bardach, Ariel, Gascón, Joaquim, Molina, Israel, Morillo, Carlos, Prado, Nilda, Riarte, Adelina, Torrico, Faustino, Villar, Juan Carlos, Reidel, Sara, Gibbons, Luz, Sosa‐Estani, Sergio

“…Objectives To determine the comparative efficacy and safety of a fixed dose of benznidazole (BZN) with an adjusted‐dose for Trypanosoma cruzi‐seropositive…”
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Response to `letter to the editor: 'Strategies to enhance access to diagnosis and treatment for Chagas disease patients in Latin America' by Alonso-Padilla, Julio, Cortés-Serra, Nuria, Pinazo, María Jesús, Bottazzi, María Elena, Abril, Marcelo, Barreira, Fabiana, Sosa-Estani, Sergio, Hotez, Peter Jay, Gascón, Joaquim

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