Search Results - "Barré, Louisa"
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Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: Differential affective and imaging correlates
Published in Alzheimer's & dementia (01-05-2017)“…Abstract Introduction Subjective cognitive decline (SCD) could indicate preclinical Alzheimer's disease, but the existing literature is confounded by…”
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Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging
Published in Neurobiology of aging (01-01-2009)“…Abstract With age, the brain undergoes both structural and functional alterations, probably resulting in reported cognitive declines. Relatively few…”
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Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia
Published in The Journal of neuroscience (14-11-2012)“…Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer's disease, but their relationships are…”
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Comparative Analysis between [18F]Fludarabine-PET and [18F]FDG-PET in a Murine Model of Inflammation
Published in Molecular pharmaceutics (06-06-2016)“…Lymphoma research has advanced thanks to introduction of [18F]fludarabine, a positron-emitting tool. This novel radiotracer has been shown to display a great…”
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Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy
Published in Scientific reports (27-05-2021)“…Lung cancer patients frequently develop brain metastases (BM). Despite aggressive treatment including neurosurgery and external-radiotherapy, overall survival…”
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[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis
Published in European journal of nuclear medicine and molecular imaging (01-08-2017)“…Purpose Hypoxia in gliomas is associated with tumor resistance to radio- and chemotherapy. However, positron emission tomography (PET) imaging of hypoxia…”
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Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: MRI and 18F-FDG PET Quantitative Analysis Using FreeSurfer
Published in BioMed research international (01-01-2015)“…Objective. The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer’s…”
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Cognitive and Brain Profiles Associated with Current Neuroimaging Biomarkers of Preclinical Alzheimer's Disease
Published in The Journal of neuroscience (22-07-2015)“…Neuroimaging biomarkers, namely hippocampal volume loss, temporoparietal hypometabolism, and neocortical β-amyloid (Aβ) deposition, are included in the recent…”
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PET imaging with [18F]AV-45 in an APP/PS1-21 murine model of amyloid plaque deposition
Published in Neurobiology of aging (01-11-2012)“…Abstract Alzheimer's disease (AD), the most common age-related neurodegenerative disorder, is characterized by the accumulation of β-amyloid peptide. In man,…”
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Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer's Disease and Mild Cognitive Impairment: MRI and (18)F-FDG PET Quantitative Analysis Using FreeSurfer
Published in BioMed research international (2015)“…The objective of this study was to compare glucose metabolism and atrophy, in the precuneus and cingulate cortex, in patients with Alzheimer's disease (AD) and…”
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[18F]Fludarabine-PET in a murine model of multiple myeloma
Published in PloS one (04-05-2017)“…Multiple myeloma (MM) is a haematological malignancy that affects plasma cells in the bone marrow. Recently, [18F]fludarabine has been introduced as an…”
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Interest of Pet Imaging in Multiple Myeloma
Published in Frontiers in medicine (2019)“…The interest of 18Fluoro-deoxyglucose (FDG) positron emission tomography (PET) imaging in the management of patients with multiple myeloma (MM) for the workup…”
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Multimodal imaging based on MRI and PET reveals [18F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma
Published in European journal of nuclear medicine and molecular imaging (01-04-2016)“…Purpose The primary objective of this study was to compare the ability of PET and MRI biomarkers to predict treatment efficacy in a preclinical model of…”
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Imaging of brain oxygenation with magnetic resonance imaging: A validation with positron emission tomography in the healthy and tumoural brain
Published in Journal of cerebral blood flow and metabolism (01-07-2017)“…The partial pressure in oxygen remains challenging to map in the brain. Two main strategies exist to obtain surrogate measures of tissue oxygenation: the…”
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FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas
Published in Scientific reports (31-08-2017)“…Quantitative imaging modalities for the analysis of hypoxia in brain tumors are lacking. The objective of this study was to generate absolute maps of tissue p…”
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Radiolabeling of HTE1PA: A new monopicolinate cyclam derivative for Cu-64 phenotypic imaging. In vitro and in vivo stability studies in mice
Published in Nuclear medicine and biology (01-05-2014)“…Abstract Introduction HTE1PA, a monopicolinate- N -alkylated cyclam-based ligand has previously demonstrated fast complexation process, high kinetic inertness…”
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[11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET)
Published in PloS one (14-09-2015)“…In quantitative PET measurements, the analysis of radiometabolites in plasma is essential for determining the exact arterial input function. Diphenyl sulfide…”
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Dihydroquinoline Carbamate Derivatives as “Bio-oxidizable” Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [11C] Radiosynthesis and Biological Evaluation
Published in ACS chemical neuroscience (20-05-2015)“…With the aim of improving the efficiency of marketed acetylcholinesterase (AChE) inhibitors in the symptomatic treatment of Alzheimer’s disease, plagued by…”
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Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation
Published in ACS chemical neuroscience (15-11-2017)“…The development of delivery systems to transport some specific radiotracers across the blood-brain barrier (BBB) needs to be investigated for brain imaging…”
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[ 18 F]-Fludarabine for Hematological Malignancies
Published in Frontiers in medicine (17-04-2019)“…With the emergence of PET/CT using F-FDG, molecular imaging has become the reference for lymphoma lesion detection, tumor staging, and response assessment…”
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