Search Results - "Barravecchia, Michael"

The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα by Bai, Haiqing, Zhou, Rui, Barravecchia, Michael, Norman, Rosemary, Friedman, Alan, Yu, Deborah, Lin, Xin, Young, Jennifer L, Dean, David A

“…An intact lung epithelial barrier is essential for lung homeostasis. The Na+, K+-ATPase (NKA), primarily serving as an ion transporter, also regulates…”
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Gene Delivery of MRCKα Repairs the Alveolar‐Capillary Barrier and Rescues the Experimental Lipopolysaccharide‐Induced Acute Lung Injury by Liu, Jing, Barravecchia, Michael, Dean, David

“…Rationale Acute Respiratory Distress Syndrome (ARDS) is a devastating condition which is characterized by the pulmonary accumulation of protein‐rich edema…”
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Electroporation-mediated gene delivery to the lungs by Young, Jennifer L, Barravecchia, Michael S, Dean, David A

“…Electroporation is a safe, efficient, and inexpensive method to transfer naked plasmid DNA into various tissues. For electroporation-mediated gene transfer to…”
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490. Electroporation-Mediated Gene Transfer of Caveolin-1 Protects from Bleomycin-Induced Pulmonary Fibrosis Through Regulating Activation of Inflammasome by Lin, Xin, Barravecchia, Michael, Dean, David A

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Caveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis by Lin, Xin, Barravecchia, Michael, Matthew Kottmann, R., Sime, Patricia, Dean, David A

“…Idiopathic pulmonary fibrosis (IPF) is a devastating and fatal disease and characterized by increased deposition of extracellular matrix proteins and scar…”
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359. Gene Transfer of the Na, K-ATPase beta1 Subunit and Occludin Using Electroporation Rescues Lipopolysaccaride (LPS)-Induced Acute Lung Injury by Lin, Xin, Barravecchia, Michael, Dean, David A.

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Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression by Lin, Xin, Bai, Haiqing, Barravecchia, Michael, Norman, Rosemary, Schiralli Lester, Gillian M, Kottmann, R. Matthew, Leonard, Antony, Rahman, Arshad, Young, Jennifer L, Dean, David A

“…Acute respiratory distress syndrome (ARDS) is a severe lung condition without targeted therapy that is characterized by the disruption of epithelial and…”
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Featured Article: Electroporation-mediated gene delivery of surfactant protein B (SP-B) restores expression and improves survival in mouse model of SP-B deficiency by Barnett, Rebecca C, Lin, Xin, Barravecchia, Michael, Norman, Rosemary A, de Mesy Bentley, Karen L, Fazal, Fabeha, Young, Jennifer L, Dean, David A

“…Surfactant Protein B Deficiency is a rare but lethal monogenetic, congenital lung disease of the neonate that is unresponsive to any treatment except lung…”
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In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development by Ávila-Pérez, Gines, Nogales, Aitor, Park, Jun-Gyu, Vasquez, Desarey Morales, Dean, David A., Barravecchia, Michael, Perez, Daniel R., Almazán, Fernando, Martínez-Sobrido, Luis

“…Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that has been known to circulate for decades causing mild febrile illness. The more…”
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Electroporation-Mediated Gene Delivery of Na+,K+-ATPase, and ENaC Subunits to the Lung Attenuates Acute Respiratory Distress Syndrome in a Two-Hit Porcine Model by Emr, Bryanna M, Roy, Shreyas, Kollisch-Singule, Michaela, Gatto, Louis A, Barravecchia, Michael, Lin, Xin, Young, Jennifer L, Wang, Guirong, Liu, Jiao, Satalin, Joshua, Snyder, Kathleen, Nieman, Gary F, Dean, David A

“…ABSTRACTIntroductionAcute respiratory distress syndrome (ARDS) is a common cause of organ failure with an associated mortality rate of 40%. The initiating…”
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MRCKα interacts with and mediates Na+, K+-ATPase-induced tight junction assembly in the lung epithelium by Bai, Haiqing, Zhou, Rui, Barravecchia, Michael, Norman, Rosemary, Friedman, Alan E., Yu, Deborah, Lin, Xin, Young, Jennifer L., Dean, David A.

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