Search Results - "Barraclough, Jane"

Increases in c-Yes Expression Level and Activity Promote Motility But Not Proliferation of Human Colorectal Carcinoma Cells by Barraclough, Jane, Hodgkinson, Cassandra, Hogg, Alison, Dive, Caroline, Welman, Arkadiusz

“…Increases in the levels and/or activity of nonreceptor tyrosine kinases c-Src and c-Yes are often associated with colorectal carcinogenesis. The physiological…”
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Generation of cells expressing improved doxycycline-regulated reverse transcriptional transactivator rtTA2S-M2 by Welman, Arkadiusz, Barraclough, Jane, Dive, Caroline

“…Tet-on cell lines engineered to stably express doxycycline (Dox)-regulated reverse transcriptional transactivator (rtTA) have many applications in biomedical…”
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Increases in c-Src Expression Level and Activity Do Not Promote the Growth of Human Colorectal Carcinoma Cells In Vitro and In Vivo by Welman, Arkadiusz, Cawthome, Christopher, Ponce-Perez, Lourdes, Barraclough, Jane, Danson, Sarah, Murray, Stephen, Cummings, Jeff, Allen, Terry D., Dive, Caroline

“…The levels and activity of c-Src in colorectal cancer cells increase steadily during the course of colorectal carcinogenesis and are most highly elevated in…”
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Cyclin D as a therapeutic target in cancer by Sutherland, Robert L, Musgrove, Elizabeth A, Caldon, C. Elizabeth, Barraclough, Jane, Stone, Andrew

“…Key Points Cyclin D–cyclin-dependent kinase 4 (CDK4) or CDK6 activation promotes cell cycle progression through the phosphorylation of substrates, including RB…”
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Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells by Caldon, C Elizabeth, Sergio, C Marcelo, Kang, Jian, Muthukaruppan, Anita, Boersma, Marijke N, Stone, Andrew, Barraclough, Jane, Lee, Christine S, Black, Michael A, Miller, Lance D, Gee, Julia M, Nicholson, Rob I, Sutherland, Robert L, Print, Cristin G, Musgrove, Elizabeth A

“…Cyclin E2, but not cyclin E1, is included in several gene signatures that predict disease progression in either tamoxifen-resistant or metastatic breast…”
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Global characterization of signalling networks associated with tamoxifen resistance in breast cancer by Browne, Brigid C, Hochgräfe, Falko, Wu, Jianmin, Millar, Ewan K. A, Barraclough, Jane, Stone, Andrew, McCloy, Rachael A, Lee, Christine S, Roberts, Caroline, Ali, Naveid A, Boulghourjian, Alice, Schmich, Fabian, Linding, Rune, Farrow, Lynn, Gee, Julia M. W, Nicholson, Robert I, O'Toole, Sandra A, Sutherland, Robert L, Musgrove, Elizabeth A, Butt, Alison J, Daly, Roger J

“…Acquired resistance to the anti‐estrogen tamoxifen remains a significant challenge in breast cancer management. In this study, we used an integrative approach…”
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Increases in c-Yes Expression Level and Activity Promote Motility But Not Proliferation of Human Colorectal Carcinoma Cells12 by Barraclough, Jane, Hodgkinson, Cassandra, Hogg, Alison, Dive, Caroline, Welman, Arkadiusz

“…Increases in the levels and/or activity of nonreceptor tyrosine kinases c-Src and c-Yes are often associated with colorectal carcinogenesis. The physiological…”
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Regulation and Roles of c-Yes in Human Colorectal Cancer by Barraclough, Jane

“…Increases in the levels and activity of the non-receptor tyrosine kinases c-Src and c-Yes are often associated with colorectal carcinogenesis. The…”
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Increases in c-Src Expression Level and Activity Do Not Promote the Growth of Human Colorectal Carcinoma Cells In Vitro and In Vivo1 by Welman, Arkadiusz, Cawthorne, Christopher, Ponce-Perez, Lourdes, Barraclough, Jane, Danson, Sarah, Murray, Stephen, Cummings, Jeff, Allen, Terry D, Dive, Caroline

“…The levels and activity of c-Src in colorectal cancer cells increase steadily during the course of colorectal carcino-genesis and are most highly elevated in…”
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Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells by Atatreh, Noor, Barraclough, Jane, Welman, Arkadiusz, Cawthorne, Christopher, Bryce, Richard A, Dive, Caroline, Freeman, Sally

“…UCS 15A, an antibiotic produced by Streptomyces sp., has been reported to specifically disrupt SH3 domain-mediated interactions in eukaryotic cells…”
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Tetracycline regulated systems in functional oncogenomics by Welman, Arkadiusz, Barraclough, Jane, Dive, Caroline

“…The increasing number of proteomic and DNA-microarray studies is continually providing a steady acquisition of data on the molecular abnormalities associated…”
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Construction and characterization of multiple human colon cancer cell lines for inducibly regulated gene expression by Welman, Arkadiusz, Cawthorne, Christopher, Barraclough, Jane, Smith, Nigel, Griffiths, Gareth J., Cowen, Rachel L., Williams, Judith C., Stratford, Ian J., Dive, Caroline

“…Validation of targets for cancer drug discovery requires robust experimental models. Systems based on inducible gene expression are well suited to this purpose…”
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System of exchange and reciprocity in “Sir Gawain and the Green Knight” by Barraclough, Jane

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