Search Results - "Barr, Travis P."

PAR2 Pepducin-Based Suppression of Inflammation and Itch in Atopic Dermatitis Models by Barr, Travis P., Garzia, Chris, Guha, Srijoy, Fletcher, Elizabeth K., Nguyen, Nga, Wieschhaus, Adam J., Ferrer, Lluis, Covic, Lidija, Kuliopulos, Athan

“…PAR2 has been proposed to contribute to lesion formation and intense itch in atopic dermatitis. Here, we tested the ability of a cell-penetrating pepducin,…”
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Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels by Barr, Travis P, Albrecht, Phillip J, Hou, Quanzhi, Mongin, Alexander A, Strichartz, Gary R, Rice, Frank L

“…Cutaneous ATP release plays an important role in both epidermal stratification and chronic pain, but little is known about ATP release mechanisms in…”
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Sensitization of cutaneous neuronal purinergic receptors contributes to endothelin-1-induced mechanical hypersensitivity by Barr, Travis P., Hrnjic, Alen, Khodorova, Alla, Sprague, Jared M., Strichartz, Gary R.

“…ETA receptor activation sensitizes neuronal P2X receptors independent of an increase in [Ca2+] and results in mechanical hypersensitivity that involves…”
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New perspectives on the endothelin axis in pain by Barr, Travis P., Kam, Sarah, Khodorova, Alla, Montmayeur, Jean-Pierre, Strichartz, Gary R.

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Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease by Gurbel, Paul A, Bliden, Kevin P, Turner, Susan E, Tantry, Udaya S, Gesheff, Martin G, Barr, Travis P, Covic, Lidija, Kuliopulos, Athan

“…OBJECTIVE—Pepducins are membrane-tethered, cell-penetrating lipopeptides that target the cytoplasmic surface of their cognate receptor. Here, we report the…”
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Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: Evidence for a role in pain by Zhao, Peng, Barr, Travis P., Hou, Quanzhi, Dib-Hajj, Sulayman D., Black, Joel A., Albrecht, Phillip J., Petersen, Karin, Eisenberg, Elon, Wymer, James P., Rice, Frank L., Waxman, Stephen G.

“…Keratinocytes are implicated in sensory transduction and can influence nociception, but whether these contribute to chronic pain is not known. In neurons,…”
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Validation of endothelin B receptor antibodies reveals two distinct receptor-related bands on Western blot by Barr, Travis P., Kornberg, Daniel, Montmayeur, Jean-Pierre, Long, Melinda, Reichheld, Stephen, Strichartz, Gary R.

“…Antibodies are important tools for the study of protein expression but are often used without full validation. In this study, we used Western blots to…”
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ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Gα(q/11) by Montmayeur, Jean-Pierre, Barr, Travis P, Kam, Sarah A, Packer, Samuel J, Strichartz, Gary R

“…Endothelin-1 (ET-1) is a pain mediator, elevated in skin after injury, which potentiates noxious thermal and mechanical stimuli (hyperalgesia) through the…”
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ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Gαq/11 by Montmayeur, Jean-Pierre, Barr, Travis P., Kam, Sarah A., Packer, Samuel J., Strichartz, Gary R.

“…Endothelin-1 (ET-1) is a pain mediator, elevated in skin after injury, which potentiates noxious thermal and mechanical stimuli (hyperalgesia) through the…”
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ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through G alpha sub(q/11) by Montmayeur, Jean-Pierre, Barr, Travis P, Kam, Sarah A, Packer, Samuel J, Strichartz, Gary R

“…Endothelin-1 (ET-1) is a pain mediator, elevated in skin after injury, which potentiates noxious thermal and mechanical stimuli (hyperalgesia) through the…”
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Elevation of Intracellular Calcium in Clonal Neuronal and Embryonic Kidney Cells Involves Endogenous Endothelin-A Receptors Linked to Phospholipase C Through Gαq/11 by Montmayeur, Jean-Pierre, Barr, Travis P., Kam, Sarah A., Packer, Samuel J., Strichartz, Gary R.

“…Endothelin-1 (ET-1) is a pain mediator, elevated in skin after injury, which potentiates noxious thermal and mechanical stimuli (hyperalgesia) through the…”
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Analysis of Keratinocyte ATP Release and Its Potential Contribution to Chronic Pain by Barr, Travis P

“…Keratinocytes release ATP, an important mediator of peripheral pain, but the mechanisms of this release have not been well characterized. ATP release in the…”
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Analysis of keratinocyte ATP release and its potential contribution to chronic pain by Barr, Travis P

“…Keratinocytes release ATP, an important mediator of peripheral pain, but the mechanisms of this release have not been well characterized. ATP release in the…”
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