Search Results - "Barr, L."
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A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome
Published in Cell reports (Cambridge) (15-11-2016)“…The three-dimensional configuration of DNA is integral to all nuclear processes in eukaryotes, yet our knowledge of the chromosome architecture is still…”
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Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome
Published in Cell (17-02-2012)“…Differential methylation of the two parental genomes in placental mammals is essential for genomic imprinting and embryogenesis. To systematically study this…”
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3
A compendium of promoter-centered long-range chromatin interactions in the human genome
Published in Nature genetics (01-10-2019)“…A large number of putative cis -regulatory sequences have been annotated in the human genome, but the genes they control remain poorly defined. To bridge this…”
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4
Trends in incidence of total or type 2 diabetes: systematic review
Published in BMJ (Online) (11-09-2019)“…AbstractObjectiveTo assess what proportions of studies reported increasing, stable, or declining trends in the incidence of diagnosed diabetes.DesignSystematic…”
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5
Viral Parkinsonism: An underdiagnosed neurological complication of Dengue virus infection
Published in PLoS neglected tropical diseases (01-02-2022)“…Dengue virus (DENV) is a flavivirus that is a significant cause of human disease costing billions of dollars per year in medical and mosquito control costs. It…”
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Rapid mitochondrial dysfunction mediates TNF‐alpha‐induced neurotoxicity
Published in Journal of neurochemistry (01-02-2015)“…Tumor necrosis factor alpha (TNF‐α) is known to exacerbate ischemic brain injury; however, the mechanism is unknown. Previous studies have evaluated the…”
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7
Chikungunya in Infants and Children: Is Pathogenesis Increasing?
Published in Viruses (23-03-2019)“…Chikungunya virus (CHIKV) was first extensively described in children during outbreaks in India and South Asia during the mid-1960s. Prior to the 2005…”
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Paediatric supracondylar humeral fractures: Epidemiology, mechanisms and incidence during school holidays
Published in Journal of children's orthopaedics (01-03-2014)“…Purpose The purpose of this study was to investigate the epidemiology of paediatric patients sustaining supracondylar humeral fractures, to identify common…”
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9
EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling
Published in Molecular cell (15-10-2015)“…Epidermal growth factor receptor (EGFR) gene amplification and mutations are the most common oncogenic events in glioblastoma (GBM), but the mechanisms by…”
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10
Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum
Published in Journal of applied toxicology (01-03-2012)“…ABSTRACT The concentrations of five esters of p‐hydroxybenzoic acid (parabens) were measured using HPLC‐MS/MS at four serial locations across the human breast…”
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11
Modulation of the Blood-Brain Barrier by Sigma-1R Activation
Published in International journal of molecular sciences (09-05-2024)“…Sigma non-opioid intracellular receptor 1 (Sigma-1R) is an intracellular chaperone protein residing on the endoplasmic reticulum at the…”
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12
Comparing the performance of six human papillomavirus tests in a screening population
Published in British journal of cancer (05-03-2013)“…Background: Several new assays have been developed for high-risk HPV testing of cervical samples; we compare six HPV tests in a screening population. Methods:…”
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13
Measurement of concentrations of four chemical ultraviolet filters in human breast tissue at serial locations across the breast
Published in Journal of applied toxicology (01-08-2018)“…The human population is widely exposed to benzophenone‐3 (BP‐3), octylmethoxycinnamate (OMC), 4‐methylbenzilidenecamphor (4‐MBC) and homosalate from their use…”
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14
Microbial Symbionts in Insects Influence Down-Regulation of Defense Genes in Maize
Published in PloS one (28-06-2010)“…Diabrotica virgifera virgifera larvae are root-feeding insects and significant pests to maize in North America and Europe. Little is known regarding how plants…”
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15
The contribution of alternative splicing to genetic risk for psychiatric disorders
Published in Genes, brain and behavior (01-03-2018)“…A genetic contribution to psychiatric disorders has clearly been established and genome‐wide association studies now provide the location of risk genes and…”
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Television Viewing Time and Mortality: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab)
Published in Circulation (New York, N.Y.) (26-01-2010)“…Television viewing time, the predominant leisure-time sedentary behavior, is associated with biomarkers of cardiometabolic risk, but its relationship with…”
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Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors
Published in Cell reports (Cambridge) (08-01-2019)“…Sigma-1 receptors (Sig-1Rs) are integral ER membrane proteins. They bind diverse ligands, including psychoactive drugs, and regulate many signaling proteins,…”
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18
Aircraft ice-nucleating particle and aerosol composition measurements in the western North American Arctic
Published in Atmospheric chemistry and physics (07-11-2023)“…Knowledge of the temperature-dependent concentration of ice-nucleating particles (INPs) is crucial to understanding the properties of mixed-phase clouds…”
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Impact of Fruit and Fruit Juice on Death and Disease Incidence: A Sex-Specific Longitudinal Analysis of 18 603 Adults
Published in Journal of the American Heart Association (05-12-2023)“…The health benefits of fruits are well established, but fruit juice has been more controversial. Fruit and juice are often ingested with other foods, which…”
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Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection
Published in Scientific reports (12-01-2015)“…The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which…”
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