Search Results - "Barr, Kevin"

Panx1 Regulates Cellular Properties of Keratinocytes and Dermal Fibroblasts in Skin Development and Wound Healing by Penuela, Silvia, Kelly, John J., Churko, Jared M., Barr, Kevin J., Berger, Amy C., Laird, Dale W.

“…Pannexin1 (Panx1), a channel-forming glycoprotein is expressed in neonatal but not in aged mouse skin. Histological staining of Panx1 knockout (KO) mouse skin…”
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Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation by Lee, Vanessa R., Barr, Kevin J., Kelly, John J., Johnston, Danielle, Brown, Cody F. C., Robb, Kevin P., Sayedyahossein, Samar, Huang, Kenneth, Gros, Robert, Flynn, Lauren E., Penuela, Silvia

“…Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally…”
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Isolation, Purification, and Culture of Embryonic Melanoblasts from Green Fluorescent Protein–expressing Reporter Mice by Crawford, Melissa, Barr, Kevin, Dagnino, Lina

“…In this article, we provide a method to isolate embryonic melanoblasts from reporter mouse strains. The mice from which these cells are isolated are bred into…”
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The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice by Stewart, Michael K G, Gong, Xiang-Qun, Barr, Kevin J, Bai, Donglin, Fishman, Glenn I, Laird, Dale W

“…Genetically modified mice mimicking ODDD (oculodentodigital dysplasia), a disease characterized by reduced Cx43 (connexin 43)-mediated gap junctional…”
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Interrogation of Carboxy-Terminus Localized GJA1 Variants Associated with Erythrokeratodermia Variabilis et Progressiva by Lucaciu, Sergiu A, Shao, Qing, Figliuzzi, Rhett, Barr, Kevin, Bai, Donglin, Laird, Dale W

“…Although inherited (encoding Cx43) gene mutations most often lead to oculodentodigital dysplasia and related disorders, four variants have been linked to…”
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Pannexin 3 deletion reduces fat accumulation and inflammation in a sex-specific manner by Wakefield, C. Brent, Lee, Vanessa R., Johnston, Danielle, Boroumand, Parastoo, Pillon, Nicolas J., Sayedyahossein, Samar, O’Donnell, Brooke L., Tang, Justin, Sanchez-Pupo, Rafael E., Barr, Kevin J., Gros, Robert, Flynn, Lauren, Borradaile, Nica M., Klip, Amira, Beier, Frank, Penuela, Silvia

“…Background Pannexin 3 (PANX3) is a channel-forming glycoprotein that enables nutrient-induced inflammation in vitro, and genetic linkage data suggest that it…”
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Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells by Freeman, Taylor J, Sayedyahossein, Samar, Johnston, Danielle, Sanchez-Pupo, Rafael E, O'Donnell, Brooke, Huang, Kenneth, Lakhani, Zameena, Nouri-Nejad, Daniel, Barr, Kevin J, Harland, Luke, Latosinsky, Steven, Grant, Aaron, Dagnino, Lina, Penuela, Silvia

“…Pannexin 1 (PANX1) is a channel-forming glycoprotein expressed in many tissues including the skin. PANX1 channels allow the passage of ions and molecules up to…”
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Mice harbouring an oculodentodigital dysplasia-linked Cx43 G60S mutation have severe hearing loss by Abitbol, Julia M, Kelly, John J, Barr, Kevin J, Allman, Brian L, Laird, Dale W

“…Given the importance of connexin43 (Cx43, encoded by ) function in the central nervous system and sensory organ processing, we proposed that it would also be…”
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Global pannexin 1 deletion increases tumor‐infiltrating lymphocytes in the BRAF/Pten mouse melanoma model by Sanchez‐Pupo, Rafael E., Finch, Garth A., Johnston, Danielle E., Craig, Heather, Abdo, Rober, Barr, Kevin, Kerfoot, Steven, Dagnino, Lina, Penuela, Silvia

“…Immunotherapies for malignant melanoma seek to boost the anti‐tumoral response of CD8+ T cells, but have a limited patient response rate, in part due to…”
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Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection by Yeaman, Michael R, Filler, Scott G, Chaili, Siyang, Barr, Kevin, Wang, Huiyuan, Kupferwasser, Deborah, Hennessey, Jr, John P, Fu, Yue, Schmidt, Clint S, Edwards, Jr, John E, Xiong, Yan Q, Ibrahim, Ashraf S

“…Significance Staphylococcus aureus is an opportunistic pathogen of the normal human flora. It is among the most frequent causes of cutaneous abscesses, leading…”
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Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus by Chan, Liana C, Chaili, Siyang, Filler, Scott G, Barr, Kevin, Wang, Huiyuan, Kupferwasser, Deborah, Edwards, Jr, John E, Xiong, Yan Q, Ibrahim, Ashraf S, Miller, Lloyd S, Schmidt, Clint S, Hennessey, Jr, John P, Yeaman, Michael R

“…Staphylococcus aureus is the leading cause of skin and skin structure infections (SSSI) in humans. Moreover, the high frequency of recurring SSSI due to S…”
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Differential effects of pannexins on noise-induced hearing loss by Abitbol, Julia M, Kelly, John J, Barr, Kevin, Schormans, Ashley L, Laird, Dale W, Allman, Brian L

“…Hearing loss, including noise-induced hearing loss, is highly prevalent and severely hinders an individual's quality of life, yet many of the mechanisms that…”
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Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis by Moon, Paxton M., Penuela, Silvia, Barr, Kevin, Khan, Sami, Pin, Christopher L., Welch, Ian, Attur, Mukundan, Abramson, Steven B., Laird, Dale W., Beier, Frank

“…Osteoarthritis (OA) is a highly prevalent, disabling joint disease with no existing therapies to slow or halt its progression. Cartilage degeneration hallmarks…”
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Global deletion of Panx3 produces multiple phenotypic effects in mouse humeri and femora by Caskenette, Deidre, Penuela, Silvia, Lee, Vanessa, Barr, Kevin, Beier, Frank, Laird, Dale W., Willmore, Katherine E.

“…Pannexins form single‐membrane channels that allow passage of small molecules between the intracellular and extracellular compartments. Of the three pannexin…”
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Decidual Angiogenesis and Placental Orientation Are Altered in Mice Heterozygous for a Dominant Loss-of-Function Gja1 (Connexin43) Mutation by WINTERHAGER, Elke, GELLHAUS, Alexandra, BLOIS, Sandra M, HILL, Lesley A, BARR, Kevin J, KIDDER, Gerald M

“…Connexin43 (CX43), encoded by Gja1 in the mouse, is highly expressed in decidual cells and is known to be important for the transformation of stromal cells…”
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Nanoporous hypercrosslinked polymers containing Tg enhancing comonomers by Zhou, Xu, Huang, Jing, Barr, Kevin W., Lin, Zhixing, Maya, Fernando, Abbott, Lauren J., Colina, Coray M., Svec, Frantisek, Turner, S. Richard

“…Hypercrosslinked polymers containing functionalized alternating copolymer sequences of substituted stilbene or styrene and N-aryl substituted maleimides have…”
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Connexin43 is required for the maintenance of multipotency in skin-derived stem cells by Dyce, Paul W, Li, Dan, Barr, Kevin J, Kidder, Gerald M

“…Expression of the gap junction protein, connexin43 (Cx43), begins early during embryogenesis and is maintained in many different cell types. Several stem cell…”
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Mutant Cx30-A88V mice exhibit hydrocephaly and sex-dependent behavioral abnormalities, implicating a functional role for Cx30 in the brain by Novielli-Kuntz, Nicole M, Press, Eric R, Barr, Kevin, Prado, Marco A M, Laird, Dale W

“…Connexin 30 (Cx30; also known as when referring to the mouse gene) is expressed in ependymal cells of the brain ventricles, in leptomeningeal cells and in…”
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Expression of pannexin isoforms in the systemic murine arterial network by Lohman, Alexander W, Billaud, Marie, Straub, Adam C, Johnstone, Scott R, Best, Angela K, Lee, Monica, Barr, Kevin, Penuela, Silvia, Laird, Dale W, Isakson, Brant E

“…Pannexins (Panx) form ATP release channels and it has been proposed that they play an important role in the regulation of vascular tone. However, distribution…”
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Comparative Analysis of Cx31 and Cx43 in Differentiation-Competent Rodent Keratinocytes by Au, Akina, Shao, Qing, White, Kyra K, Lucaciu, Sergiu A, Esseltine, Jessica L, Barr, Kevin, Laird, Dale W

“…When considering connexin expression and regulation, the epidermis of the skin is one of the most complex tissues found in mammals even though it largely…”
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