Search Results - "Baroni, Silvia"
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Decreased serum levels of the inflammaging marker miR-146a are associated with clinical non-response to tocilizumab in COVID-19 patients
Published in Mechanisms of ageing and development (01-01-2021)“…•Tocilizumab (TCZ) is currently being tested in COVID‐19‐induced cytokine storm.•COVID-19 patients responding to TCZ have higher post-treatment levels of…”
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Agonistic antibodies in systemic sclerosis
Published in Immunology letters (01-03-2018)“…•Agonistic antibodies activate pathways leading to tissue and vascular damage in SSc.•Anti-endothelial cells antibodies (AECA) can induce either apoptosis or…”
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Mesenchymal stromal cells from human umbilical cord prevent the development of lung fibrosis in immunocompetent mice
Published in PloS one (01-06-2018)“…Lung fibrosis is a severe condition resulting from several interstial lung diseases (ILD) with different etiologies. Current therapy of ILD, especially those…”
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Screening and Analysis of Possible Drugs Binding to PDGFRα: A Molecular Modeling Study
Published in International journal of molecular sciences (01-06-2023)“…The platelet-derived growth factor receptor (PDGFR) is a membrane tyrosine kinase receptor involved in several metabolic pathways, not only physiological but…”
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A Reactive Oxygen Species–Mediated Loop Maintains Increased Expression of NADPH Oxidases 2 and 4 in Skin Fibroblasts From Patients With Systemic Sclerosis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2015)“…Objective Reactive oxygen species (ROS) contribute to the pathogenesis of fibrosis in systemic sclerosis (SSc; scleroderma), and NADPH oxidase (NOX) is an…”
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Induction of Scleroderma Fibrosis in Skin‐Humanized Mice by Administration of Anti−Platelet‐Derived Growth Factor Receptor Agonistic Autoantibodies
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2016)“…Objective To describe a skin–SCID mouse chimeric model of systemic sclerosis (SSc; scleroderma) fibrosis based on engraftment of ex vivo–bioengineered skin…”
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Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis
Published in The New England journal of medicine (22-06-2006)“…The pathophysiology of systemic sclerosis (scleroderma), an autoimmune disease characterized by injury of endothelial cells, and tissue fibrosis, is undefined…”
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Circulating miR-320b and miR-483-5p levels are associated with COVID-19 in-hospital mortality
Published in Mechanisms of ageing and development (01-03-2022)“…The stratification of mortality risk in COVID-19 patients remains extremely challenging for physicians, especially in older patients. Innovative minimally…”
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Mapping of Urinary Volatile Organic Compounds by a Rapid Analytical Method Using Gas Chromatography Coupled to Ion Mobility Spectrometry (GC–IMS)
Published in Metabolites (01-11-2022)“…Volatile organic compounds (VOCs) are a differentiated class of molecules, continuously generated in the human body and released as products of metabolic…”
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Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2
Published in Arthritis research & therapy (17-03-2015)“…Abnormal oxidative stress has been described in systemic sclerosis (SSc) and previous works from our laboratory demonstrated an increased generation of…”
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Association between TNF-α, cortisol levels, and exposure to PM10 and PM2.5: a pilot study
Published in Environmental sciences Europe (07-08-2024)“…Purpose The most harmful atmospheric pollutant for human health is particulate matter (PM). We analyzed the correlation between short-term lag exposure to PM10…”
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Assessment of sST2 Behaviors to Evaluate Severity/Clinical Impact of Acute Pulmonary Embolism
Published in International journal of molecular sciences (27-02-2023)“…Pulmonary embolism (PE) is a potentially life-threatening disorder. Beyond its usefulness in the prognostic stratification of heart failure, sST2 can represent…”
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Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?
Published in Protein and peptide letters (01-01-2020)“…Male hypogonadism is "a clinical syndrome that results from failure of the testis to produce physiological concentrations of testosterone and/or a normal…”
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Use of an innovative cuff pressure control and subglottic secretions drainage system in COVID-19 ARDS patients undergoing pronation
Published in Critical care (London, England) (04-11-2022)“…Abstract We conducted a proof of concept study where Anapnoguard endotracheal tubes and its control unit were used in 15 patients with COVID-19 acute…”
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Putative functional pathogenic autoantibodies in systemic sclerosis
Published in European journal of rheumatology (01-10-2020)“…Systemic sclerosis (scleroderma, SSc) is a systemic disease characterized by vascular lesions, fibrosis, and circulating autoantibodies. A complex interplay…”
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Calprotectin in nasal secretion: a new biomarker of non-type 2 inflammation in CRSwNP
Published in Acta otorhino-laryngologica italica (01-08-2022)“…ObjectiveWe analysed calprotectin in sinonasal secretions of different chronic rhinosinusitis with nasal polyps (CRSwNP) endotypes to assess its role as a…”
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Role of Intestinal Inflammation and Permeability in Patients with Acute Heart Failure
Published in Medicina (Kaunas, Lithuania) (01-01-2024)“…: Heart failure (HF) represents a major health burden. Although several treatment regimens are available, their effectiveness is often unsatisfactory. Growing…”
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Post-exercise high-sensitivity troponin T levels in patients with suspected unstable angina
Published in PloS one (09-09-2019)“…Previous studies showed that troponin blood levels may increase after exercise. In this study we assessed whether, among patients admitted with suspected…”
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Olfactory Receptors in Semen and in the Male Tract: From Proteome to Proteins
Published in Frontiers in endocrinology (Lausanne) (23-01-2018)“…The estimated number of testicular olfactory receptors (ORs) in mammals range between 20 and 66. Previous data reported the role of hOR17-4 and mOR23 in…”
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On Nature's Strategy for Assigning Genetic Code Multiplicity
Published in PloS one (05-02-2016)“…Genetic code redundancy would yield, on the average, the assignment of three codons for each of the natural amino acids. The fact that this number is observed…”
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