Search Results - "Barone, MV"
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Steroid-induced androgen receptor-oestradiol receptor β-Src complex triggers prostate cancer cell proliferation
Published in The EMBO journal (16-10-2000)“…Treatment of human prostate carcinoma‐derived LNCaP cells with androgen or oestradiol triggers simultaneous association of androgen receptor and oestradiol…”
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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
Published in The EMBO journal (01-11-2001)“…The p85‐associated phosphatidylinositol (PI) 3‐kinase/Akt pathway mediates the oestradiol‐induced S‐phase entry and cyclin D1 promoter activity in MCF‐7 cells…”
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The Role of Microdomains in Beta-Adrenoreceptor Signalling266Metoprolol induces cardiac beta-3 adrenergic receptor and Sphingosine 1 phosphate receptor 1 signals to prevent adverse Left-ventricle remodeling and dysfunction after myocardial infarction267PDE8 is a novel regulator of cAMP signaling in human atrial fibrillation268B-blocker therapy in heart failure reduces migratory and proliferative properties of primarily cultured failing cardiac fibroblasts via reduction of g protein-coupled recep
Published in Cardiovascular research (01-07-2016)Get full text
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Androgen-Stimulated DNA Synthesis and Cytoskeletal Changes in Fibroblasts by a Nontranscriptional Receptor Action
Published in The Journal of cell biology (12-05-2003)“…In NIH3T3 cells, 0.001 nM of the synthetic androgen R1881 induces and stimulates association of androgen receptor (AR) with Src and phosphatidylinositol…”
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Non-transcriptional action of oestradiol and progestin triggers DNA synthesis
Published in The EMBO journal (04-05-1999)“…The recent findings that oestradiol and progestins activate the Src/Ras/Erks signalling pathway raise the question of the role of this stimulation…”
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A Novel Peroxisome Proliferator-activated Receptor γ Isoform with Dominant Negative Activity Generated by Alternative Splicing
Published in The Journal of biological chemistry (15-07-2005)“…We examined the peroxisome proliferator-activated receptor γ (PPARG) locus in an attempt to identify expressed sequence tags and/or conserved non-coding…”
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Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src
Published in Nature (London) (30-11-1995)“…Growth factors such as platelet-derived growth factor (PDGF) elicit the transcriptional activation of a large number of immediate early genes (many of which…”
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Rapid signalling pathway activation by androgens in epithelial and stromal cells
Published in Steroids (01-08-2004)“…Estradiol rapidly activates Src as well as the Src-dependent pathway in human mammary cancer-derived MCF-7 cells, in human prostate cancer-derived LNCaP cells…”
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Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells
Published in The Journal of clinical investigation (01-10-1999)“…The majority of thyroid carcinomas maintain the expression of the cell growth suppressor p27, an inhibitor of cyclin-dependent kinase-2 (Cdk2). However, we…”
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DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases
Published in Molecular and Cellular Biology (01-02-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Induction of ETS-1 and ETS-2 transcription factors is required for thyroid cell transformation
Published in Cancer research (Chicago, Ill.) (01-03-2001)“…The proteins of the Ets family are transcription factors involved in signal transduction, cell cycle progression, and differentiation. In this study, we report…”
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Id Proteins Control Growth Induction in Mammalian Cells
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-1994)“…Id1, Id2, and Id3 (HLH462) dimerize with members of the basic helix-loop-helix protein family, but due to the absence of the basic region, the resulting…”
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Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins
Published in The journal of clinical endocrinology and metabolism (01-10-2000)“…Point mutations of the RET receptor tyrosine kinase are responsible for the inheritance of multiple endocrine neoplasia (MEN) type 2 syndromes and are also…”
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Dietary Proteins and Mechanisms of Gastrointestinal Diseases: Gliadin as a Model
Published in Journal of pediatric gastroenterology and nutrition (01-06-2004)Get full text
Journal Article Conference Proceeding -
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The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane
Published in Oncogene (01-02-2001)“…The RET/PTC3 oncogene arises from the fusion between the N-terminal encoding domain of the RFG gene and the tyrosine kinase encoding domain of RET receptor…”
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Urokinase receptor-dependent and -independent p56/59(hck) activation state is a molecular switch between myelomonocytic cell motility and adherence
Published in The EMBO journal (01-06-1999)“…Anchorage-independent myelomonocytic cells acquire adherence within minutes of differentiation stimuli, such as the proteolytically inactive N-terminal…”
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Ret-mediated mitogenesis requires Src kinase activity
Published in Cancer research (Chicago, Ill.) (01-03-1999)“…The proto-oncogene RET encodes a transmembrane growth neurotrophic receptor with tyrosine kinase (TK) activity. RET mutations are associated with several human…”
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