Search Results - "Baron, Shoshana"

Measurement of lymphocyte aggregation by flow cytometry-physiological implications in chronic lymphocytic leukemia by Dezorella, Nili, Kay, Sigi, Baron, Shoshana, Shapiro, Mika, Porat, Ziv, Deutsch, Varda, Herishanu, Yair, Katz, Ben-Zion

“…Background Cellular aggregation is a physiological response of lymphocytes to various extracellular stimuli. Currently, lymphocytes aggregation is only…”
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New Xenograft Method For Studying Leukemia and Drug Response In Turkey Embryos by Deutsch, Varda R, Kay, Sigi, Farnoushi, Yona, Matalon, Erez, Ohayon, Tal, Baron, Shoshana, Jan, Hila, Naparstek, Elizabeth, Cipok, Michal

“…A widely accepted in vivo model for studying leukemia and its treatment is the highly immune-deficient mice NOD/SCID (b2M-/- or rag-/-). While this model is…”
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Mesenchymal stromal cells revert multiple myeloma cells to less differentiated phenotype by the combined activities of adhesive interactions and interleukin-6 by Dezorella, Nili, Pevsner-Fischer, Meirav, Deutsch, Varda, Kay, Sigi, Baron, Shoshana, Stern, Ruth, Tavor, Sigal, Nagler, Arnon, Naparstek, Elizabeth, Zipori, Dov, Katz, Ben-Zion

“…Multiple myeloma is characterized by the malignant growth of immunoglobulin producing plasma cells, predominantly in the bone marrow. The effects of primary…”
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Divergence in CD19-mediated signaling unfolds intraclonal diversity in chronic lymphocytic leukemia, which correlates with disease progression by Herishanu, Yair, Kay, Sigi, Dezorella, Nili, Baron, Shoshana, Hazan-Halevy, Inbal, Porat, Ziv, Trestman, Svetlana, Perry, Chava, Braunstein, Rony, Deutsch, Varda, Polliack, Aaron, Naparstek, Elizabeth, Katz, Ben-Zion

“…Emerging data on intraclonal diversity imply that this phenomenon may play a role in the clinical outcome of patients with chronic lymphocytic leukemia (CLL),…”
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Integration of automated morphological features resolves a distinct group of atypical chronic lymphocytic leukemias with chromosomal aberrations by Herishanu, Yair, Kay, Sigi, Joffe, Erel, Ben-Ezra, Jonathan, Baron, Shoshana, Rotman, Rachel, Braunstein, Rony, Dezorella, Nili, Polliack, Aaron, Naparstek, Elizabeth, Perry, Chava, Deutsch, Varda, Katz, Ben-Zion

“…Abstract Automated morphological assessment of peripheral blood slides has become an important modality facilitating characterization and quantification of…”
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The generation and regulation of functional diversity of malignant plasma cells by NADAV, Liat, KATZ, Ben-Zion, BARON, Shoshana, COHEN, Nir, NAPARSTEK, Elizabeth, GEIGER, Benjamin

“…Cellular diversity, which is a hallmark of malignancy, can be generated by both genetic and nongenetic mechanisms. We describe here variability in the adhesive…”
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Diverse niches within multiple myeloma bone marrow aspirates affect plasma cell enumeration by Nadav, Liat, Katz, Ben‐Zion, Baron, Shoshana, Yossipov, Lydia, Polliack, Aaron, Deutsch, Varda, Geiger, Benjamin, Naparstek, Ellizabeth

“…Summary A basic criterion for the diagnosis of multiple myeloma is plasma cell enumeration within the bone marrow (BM). This report showed that flow cytometry…”
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MUC1/X protein immunization enhances cDNA immunization in generating anti-MUC1 alpha/beta junction antibodies that target malignant cells by Rubinstein, Daniel B, Karmely, Maya, Ziv, Ravit, Benhar, Itai, Leitner, Orit, Baron, Shoshana, Katz, Ben-Zion, Wreschner, Daniel H

“…MUC1 has generated considerable interest as a tumor marker and potential target for tumor killing. To date, most antibodies against MUC1 recognize epitopes…”
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Quantitative flow cytometry of ZAP‐70 levels in chronic lymphocytic leukemia using molecules of equivalent soluble fluorochrome by Kay, Sigi, Herishanu, Yair, Pick, Marjorie, Rogowski, Ori, Baron, Shoshana, Naparstek, Elizabeth, Polliack, Aaron, Deutsch, Varda R.

“…Background ZAP‐70 has emerged as a potential pivotal prognostic marker for patients with chronic lymphocytic leukemia (CLL), which could replace immunoglobulin…”
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The CXCR4 Antagonist AMD3100 Impairs Survival of AML Cells and Induces Their Differentiation by Tavor, Sigal, Eisenbach, Manny, Jacob-Hirsch, Jasmine, Golan, Tammar, Petit, Isabelle, Ben-Zion, Katz, Kay, Sigi, Baron, Shoshana, Amariglio, Ninette, Deutsch, Varda, Naparstek, Elizabeth, Rechavi, Gideon

“…The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, participate in the retention of AML cells within the bone marrow microenvironment…”
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2.7 Intra-Clonal Diversity Identified by CD19-Mediated Signaling Correlates with Disease Progression in CLL by Herishanu, Yair, Kay, Sigi, Dezorella, Nili, Baron, Shoshana, Hazan-Halevy, Inbal, Trestman, Svetlana, Perry, Chava, Braunstein, Rony, Deutsch, Varda, Polliack, Aaron, Naparstek, Elizabeth, Katz, Ben-Zion

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MUC1/X Protein Immunization Enhances cDNA Immunization in Generating Anti-MUC1 alpha /{beta} Junction Antibodies that Target Malignant Cells by Rubinstein, Daniel B, Karmely, Maya, Ziv, Ravit, Benhar, Itai, Leitner, Orit, Baron, Shoshana, Katz, Ben-Zion, Wreschner, Daniel H

“…MUC1 has generated considerable interest as a tumor marker and potential target for tumor killing. To date, most antibodies against MUC1 recognize epitopes…”
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Inhibition of Elastase or SDF-1/CXCR4 Axis Promotes Differentiation of Human AML Cells by Tavor, Sigal, Jacob-Hirsch, Jasmine, Eisenbach, Manny, Kay, Sigi, Baron, Shoshana, Amariglio, Ninette, Naparstek, Elizabeth, Rechavi, Gideon

“…Elastase, along with other azurophil granule proteins like proteinase 3 regulates normal and leukemic granulopoiesis in an un-defined mechanism. We have…”
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The Location of Multiple Myeloma Adhesion Variants in Diverse Niches within the Bone Marrow Affects Plasma Cells Enumeration by Nadav, Liat, Katz, Ben-Zion, Baron, Shoshana, Lydia, Lydia, Polliack, Aaron, Deutsch, Varda, Geiger, Benjamin, Naparstek, Elizabeth

“…Background - The diagnosis of multiple myeloma (MM) is based on clinical and laboratory criteria combined with bone marrow (BM) plasmocytosis, estimated by…”
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short report: Diverse niches within multiple myeloma bone marrow aspirates affect plasma cell enumeration by Nadav, Liat, Katz, Ben-Zion, Baron, Shoshana, Yossipov, Lydia, Polliack, Aaron, Deutsch, Varda, Geiger, Benjamin, Naparstek, Ellizabeth

“…A basic criterion for the diagnosis of multiple myeloma is plasma cell enumeration within the bone marrow (BM). This report showed that flow cytometry…”
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MUC1/X protein immunization enhances cDNA immunization in generating anti-MUd α/β junction antibodies that target malignant cells by RUBINSTEIN, Daniel B, KARMELY, Maya, ZIV, Ravit, BENHAR, Itai, LEITNER, Orit, BARON, Shoshana, KATZ, Ben-Zion, WRESCHNER, Daniel H

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Quantitation of Zap-70 Expression in B-CLLCells Employing a Novel Flow Cytometry Analysis Method by Deutsch, Varda R., Kay, Sigi, Pick, Marjorie, Herishanu, Yair, Rogowsky, Ori, Baron, Shoshana, Naparstek, Elizabeth, Polliack, Aaron

“…IgVH mutational status and molecular cytogenetics have dramatically improved the ability to predict the prognosis of CLL patients. These tests, however, are…”
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Phenotype and function of lymphocytes from the neonatal umbilical cord compared to paired maternal peripheral blood cells isolated during delivery by Eisenthal, Avi, Hassner, Avi, Shenav, Michael, Baron, Shoshana, Lifschitz-Mercer, Beatriz

“…In the present study, we analyzed the immunological characteristics of mononuclear cells (MNC) isolated from both neonatal umbilical cord blood (UCB) and…”
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Decrease of intracellular fluorescein fluorescence polarization (IFFP) in human peripheral blood lymphocytes undergoing stimulation with phytohaemagglutinin (PHA), concanavalin A (ConA), pokeweed mitogen (PWM) and anti-CD3 antibody by Eisenthal, Avi, Marder, Oleg, Dotan, Dalia, Baron, Shoshana, Lifschitz-Mercer, Beatriz, Chaitchik, Samario, Tirosh, Reuven, Weinreb, Arye, Deutsch, Motti

“…In the present study we describe the induction of changes in intracellular fluorescein fluorescence polarization (IFFP) in lymphocytes undergoing activation…”
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Inhibition of CT-26 murine adenocarcinoma growth in the rectum of mice treated with recombinant human interleukin-6 by Rabau, M, Kashtan, H, Baron, S, Yossiphov, J, Skornik, Y, Revel, M, Eisenthal, A

“…In the present study we evaluated the antitumor effects of recombinant human interleukin-6 (rhIL-6), expressed in Chinese hamster ovary cells, in a murine…”
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