Search Results - "Baron, Ralf"
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Diagnosis and assessment of neuropathic pain through questionnaires
Published in Lancet neurology (01-05-2018)“…Neuropathic pain—pain caused by a lesion or disease of the somatosensory nervous system—is underdiagnosed and difficult to treat. However, development of…”
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Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain
Published in Nature reviews. Neurology (01-12-2014)“…Key Points Chemotherapy-induced peripheral neuropathic pain (CIPNP) affects up to 80% of patients during chemotherapy; it is a severe adverse effect that can…”
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Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment
Published in Lancet neurology (01-08-2010)“…Summary Neuropathic pain develops as a result of lesions or disease affecting the somatosensory nervous system either in the periphery or centrally. Examples…”
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Neuropathic Pain: Principles of Diagnosis and Treatment
Published in Mayo Clinic proceedings (01-04-2015)“…Abstract Neuropathic pain is caused by disease or injury of the nervous system and includes various chronic conditions that, together, affect up to 8% of the…”
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Chronic nociplastic pain affecting the musculoskeletal system: clinical criteria and grading system
Published in Pain (Amsterdam) (01-11-2021)Get full text
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Assessment of Chronic Pain: Domains, Methods, and Mechanisms
Published in The journal of pain (01-09-2016)“…Accurate classification of chronic pain conditions requires reliable and valid pain assessment. Moreover, pain assessment serves several additional functions,…”
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Do we need a third mechanistic descriptor for chronic pain states?
Published in Pain (Amsterdam) (01-07-2016)Get full text
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Peripheral input and its importance for central sensitization
Published in Annals of neurology (01-11-2013)“…Many pain states begin with damage to tissue and/or nerves in the periphery, leading to enhanced transmitter release within the spinal cord and central…”
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The painDETECT project - far more than a screening tool on neuropathic pain
Published in Current medical research and opinion (02-06-2016)“…Background and objectives The painDETECT questionnaire (PD-Q), a simple and reliable screening questionnaire of neuropathic pain, was developed in 2004 in…”
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Clinical features and pathophysiology of complex regional pain syndrome
Published in Lancet neurology (01-07-2011)“…Summary A complex regional pain syndrome (CRPS)—multiple system dysfunction, severe and often chronic pain, and disability—can be triggered by a minor injury,…”
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Subgrouping of patients with neuropathic pain according to pain-related sensory abnormalities: a first step to a stratified treatment approach
Published in Lancet neurology (01-11-2012)“…Summary Background Patients with neuropathic pain present with various pain-related sensory abnormalities. These sensory features form different patterns or…”
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Osteoarthritis pain: nociceptive or neuropathic?
Published in Nature reviews. Rheumatology (01-06-2014)“…The most common symptom of osteoarthritis is pain, but current treatments do not identify or treat different types of osteoarthritis-associated pain. In this…”
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Deconstructing the Neuropathic Pain Phenotype to Reveal Neural Mechanisms
Published in Neuron (Cambridge, Mass.) (23-02-2012)“…After nerve injury maladaptive changes can occur in injured sensory neurons and along the entire nociceptive pathway within the CNS, which may lead to…”
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Neuropathic pain: an updated grading system for research and clinical practice
Published in Pain (Amsterdam) (01-08-2016)“…The redefinition of neuropathic pain as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system," which was suggested…”
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Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis
Published in Lancet neurology (01-02-2015)“…Summary Background New drug treatments, clinical trials, and standards of quality for assessment of evidence justify an update of evidence-based…”
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Reference data for quantitative sensory testing (QST): Refined stratification for age and a novel method for statistical comparison of group data
Published in Pain (Amsterdam) (01-12-2010)“…Clinical use of quantitative sensory testing (QST) requires standardization. The German research network on neuropathic pain (DFNS) solves this problem by…”
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Mechanism-based treatment in complex regional pain syndromes
Published in Nature reviews. Neurology (01-09-2014)“…Key Points Complex regional pain syndromes (CRPS) are multifactorial disorders; the heterogeneity of clinical signs and symptoms reflects different underlying…”
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The cornucopia of central disinhibition pain – An evaluation of past and novel concepts
Published in Neurobiology of disease (01-11-2020)“…Central disinhibition (CD), as applied to pain, decreases thresholds of endogenous systems. This provokes onset of spontaneous or evoked pain in an individual…”
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Interventional management of neuropathic pain: NeuPSIG recommendations
Published in Pain (Amsterdam) (01-11-2013)“…Neuropathic pain (NP) is often refractory to pharmacologic and noninterventional treatment. On behalf of the International Association for the Study of Pain…”
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