Search Results - "Barnum, SR"

Differential expression of beta sub(2)-integrins and cytokine production between gamma delta and alpha beta T cells in experimental autoimmune encephalomyelitis by Smith, S S, Barnum, SR

“…The expression of beta sub(2)-integrins on gamma delta T cells in naive mice or those with experimental autoimmune encephalomyelitis (EAE) remains poorly…”
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Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis by Dugger, Kari J, Zinn, Kurt R, Weaver, Casey, Bullard, Daniel C, Barnum, Scott R

“…Abstract LFA-1 (CD11a/CD18) is a member of the β2 -integrin family of adhesion molecules important in leukocyte trafficking and activation. Although LFA-1 is…”
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Complement in central nervous system inflammation by Barnum, Scott R

“…The complement system is well represented in the central nervous system. Glial cells and neurons produce or express all of the activation and regulatory…”
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p150/95 (CD11c/CD18) Expression Is Required for the Development of Experimental Autoimmune Encephalomyelitis by Bullard, Daniel C, Hu, Xianzhen, Adams, Jillian E, Schoeb, Trenton R, Barnum, Scott R

“…p150/95 (CD11c/CD18, CR4) is a member of the β2 -integrin family of adhesion molecules and is considered an important phagocytic receptor. The role of p150/95…”
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Deletion of the complement phagocytic receptors CR3 and CR4 does not alter susceptibility to experimental cerebral malaria by RAMOS, T. N., BULLARD, D. C., BARNUM, S. R.

“…Summary Complement receptors for C3‐derived fragments (CR1–4) play critical roles in innate and adaptive immune responses. Of these receptors, CR3 and CR4 are…”
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Human T Cells Express the C5a Receptor and Are Chemoattracted to C5a by Nataf, Serge, Davoust, Nathalie, Ames, Robert S, Barnum, Scott R

“…The anaphylatoxin C5a is a potent mediator of inflammation that exerts a broad range of activity on cells of the myeloid lineage. In this study, we present the…”
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C3a expressed in the central nervous system protects against LPS-induced shock by Boos, Laura, Szalai, Alexander J., Barnum, Scott R.

“…Complement is implicated in the pathogenesis of inflammatory disorders of the central nervous system (CNS), like multiple sclerosis, Alzheimer's disease, and…”
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Deletion of carboxypeptidase N delays onset of experimental cerebral malaria by DARLEY, M. M., RAMOS, T. N., WETSEL, R. A., BARNUM, S. R.

“…Summary Complement contributes to inflammation during pathogen infections; however, less is known regarding its role during malaria and in the severest form of…”
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Experimental Allergic Encephalomyelitis Is Inhibited in Transgenic Mice Expressing Human C-Reactive Protein by Szalai, Alexander J, Nataf, Serge, Hu, Xian-Zhen, Barnum, Scott R

“…We show here using a transgenic model that human C-reactive protein (CRP) protects against experimental allergic encephalomyelitis (EAE) in C57BL/6 mice. In…”
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Complement anaphylatoxin receptors on neurons: new tricks for old receptors? by Nataf, Serge, Stahel, Philip F., Davoust, Nathalie, Barnum, Scott R.

“…Activation of the complement system has been reported in a variety of inflammatory diseases and neurodegenerative processes of the CNS. Recent evidence…”
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PSGL-1 is not required for development of experimental autoimmune encephalomyelitis by Osmers, Inga, Bullard, Daniel C., Barnum, Scott R.

“…Adhesion molecules are essential mediators for lymphocyte trafficking through the blood–brain barrier into the CNS in multiple sclerosis and its animal model…”
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Molecular phylogeny of the heterocystous cyanobacteria (subsections IV and V) based on nifD by Henson, Brian J, Hesselbrock, Sharon M, Watson, Linda E, Barnum, Susan R

“…Department of Botany, Miami University, Oxford, OH 45056, USA Correspondence Susan R. Barnum barnumsr{at}muohio.edu The heterocystous cyanobacteria are…”
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Attenuation of Experimental Autoimmune Demyelination in Complement-Deficient Mice by Nataf, Serge, Carroll, Steven L, Wetsel, Rick A, Szalai, Alexander J, Barnum, Scott R

“…The exact mechanisms leading to CNS inflammation and myelin destruction in multiple sclerosis and in its animal model, experimental allergic encephalomyelitis…”
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Receptor for the C3a anaphylatoxin is expressed by neurons and glial cells by Davoust, Nathalie, Jones, Jennifer, Stahel, Philip F., Ames, Robert S., Barnum, Scott R.

“…Little is known about the expression of the receptor for complement anaphylatoxin C3a (C3aR) in the central nervous system (CNS). In this study, we provide the…”
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Disruption of the beta sub(2)-integrin CD11d ( alpha sub(D) beta 2) gene fails to protect against experimental autoimmune encephalomyelitis by Adams, JE, Webb, MS, Hu, X, Staunton, D, Barnum, SR

“…The fourth member of the beta sub(2)-integrin family of adhesion molecules, CD11d ( alpha sub(D) beta sub(2)), is expressed on a wide variety of immune cells,…”
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Central Nervous System-Targeted Expression of the Complement Inhibitor sCrry Prevents Experimental Allergic Encephalomyelitis by Davoust, Nathalie, Nataf, Serge, Reiman, Rachael, V. Holers, Michael, Campbell, Iain L, Barnum, Scott R

“…Although generally thought of as a T cell-driven autoimmune disease, recent studies in experimental allergic encephalomyelitis (EAE), the animal model of…”
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Disruption of the C5a receptor gene fails to protect against experimental allergic encephalomyelitis by Reiman, Rachael, Gerard, Craig, Campbell, Iain L., Barnum, Scott R.

“…Activation of the complement system generates the anaphylatoxic peptide C5a, which elicits a broad range of inflammatory activities. The biological activities…”
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Expression of C5a in the brain does not exacerbate experimental autoimmune encephalomyelitis by Reiman, Rachael, Torres, Antonio Campos, Martin, Brian K., Ting, Jenny P., Campbell, Iain L., Barnum, Scott R.

“…Complement is implicated in the pathology of neurodegenerative and inflammatory disease in the central nervous system (CNS). Although studies demonstrate that…”
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Deletion of the G2A receptor fails to attenuate experimental autoimmune encephalomyelitis by Osmers, Inga, Smith, Sherry S, Parks, Brian W, Yu, Shaohua, Srivastava, Roshni, Wohler, Jillian E, Barnum, Scott R, Kabarowski, Janusz H.S

“…Abstract Lysophosphatidylcholine (LPC) is a chemotactic lysolipid produced during inflammation by the hydrolytic action of phospholipase A2 enzymes. LPC…”
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The evolutionary history of nitrogen fixation, as assessed by NifD by Henson, Brian J, Watson, Linda E, Barnum, Susan R

“…The evolutionary history of nitrogen fixation has been vigorously debated for almost two decades. Previous phylogenetic analyses of nitrogen fixation genes…”
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