Search Results - "Barnholt, Kimberly E."

Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms by Hinds, David A., Barnholt, Kimberly E., Mesa, Ruben A., Kiefer, Amy K., Do, Chuong B., Eriksson, Nicholas, Mountain, Joanna L., Francke, Uta, Tung, Joyce Y., Nguyen, Huong (Marie), Zhang, Haiyu, Gojenola, Linda, Zehnder, James L., Gotlib, Jason

“…We conducted a genome-wide association study (GWAS) to identify novel predisposition alleles associated with Philadelphia chromosome-negative…”
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Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation by Barnholt, Kimberly E, Kota, Rama S, Aung, Hnin Hnin, Rutledge, John C

“…Macrophages are activated by IFN-gamma, a proinflammatory and proatherogenic cytokine that mediates its downstream effects primarily through STAT1. IFN-gamma…”
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Sildenafil improves cardiac output and exercise performance during acute hypoxia, but not normoxia by Hsu, Andrew R, Barnholt, Kimberly E, Grundmann, Nicolas K, Lin, Joseph H, McCallum, Stewart W, Friedlander, Anne L

“…1 Exercise Physiology Laboratory, Clinical Studies Unit, Veterans Affairs Palo Alto Health Care System, 2 Department of Medicine, Pulmonary and Critical Care,…”
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Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction by Barnholt, Kimberly E, Hoffman, Andrew R, Rock, Paul B, Muza, Stephen R, Fulco, Charles S, Braun, Barry, Holloway, Leah, Mazzeo, Robert S, Cymerman, Allen, Friedlander, Anne L

“…High-altitude anorexia leads to a hormonal response pattern modulated by both hypoxia and caloric restriction (CR). The purpose of this study was to compare…”
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Genome-wide analysis and characterization of an online sarcoma cohort by Barnholt, Kimberly E, Do, Chuong B, Kiefer, Amy K, Nelson, Marisa, Garber, Judy Ellen, Robson, Mark E., Maki, Robert G., Demetri, George D., Wojcicki, Anne

“…Abstract only 10097 Background: Recruitment of an adequately sized cohort for genome-wide studies presents a serious challenge for rare diseases such as…”
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Estimation of JAK2 V617F Prevalence by Detection of the Mutation in Saliva Samples From Online MPN and General Population Cohorts by Barnholt, Kimberly E., Hinds, David A., Kiefer, Amy K., Do, Chuong B., Eriksson, Nicholas, Mountain, Joanna L., Francke, Uta, Tung, Joyce A., Nguyen, Huong (Marie), Levine, Ross L., Mesa, Ruben A., Gotlib, Jason, Zehnder, James L.

“…Abstract 1737 The somatic JAK2 V617F (V617F) mutation is found in approximately 95% of polycythemia vera (PV) and 50–60% of essential thrombocythemia (ET) and…”
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A Germline Variant in the TERT Gene Is a Novel Predisposition Allele Associated with Myeloproliferative Neoplasms by Hinds, David A., Barnholt, Kimberly E., Zehnder, James L., Kiefer, Amy K., Do, Chuong B., Eriksson, Nicholas, Mountain, Joanna L., Francke, Uta, Tung, Joyce A., Nguyen, Huong (Marie), Levine, Ross L., Mesa, Ruben A., Gotlib, Jason

“…Abstract 707 Myeloproliferative neoplasms (MPNs) are disorders that result in unregulated overproduction of one or more myeloid blood cell types by the bone…”
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Correlation of Symptom Assessment with Genotyping Analysis of Saliva Samples in a Large Cohort of Myeloproliferative Neoplasm Patients by Nguyen, Huong (Marie), Hinds, David A., Barnholt, Kimberly E., Kiefer, Amy K., Do, Chuong B., Eriksson, Nicholas, Mountain, Joanna L., Francke, Uta, Tung, Joyce A., Levine, Ross L., Zehnder, James L., Gotlib, Jason, Mesa, Ruben A.

“…Abstract 1732 In addition to chronic myelogenous leukemia (CML), the classic myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential…”
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Adenosine Blocks IFN-γ-Induced Phosphorylation of STAT1 on Serine 727 to Reduce Macrophage Activation1 by Barnholt, Kimberly E., Kota, Rama S., Aung, Hnin Hnin, Rutledge, John C.

“…Macrophages are activated by IFN- γ , a proinflammatory and proatherogenic cytokine that mediates its downstream effects primarily through STAT1. IFN- γ…”
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Adenosine Blocks IFN-{gamma}-Induced Phosphorylation of STAT1 on Serine 727 to Reduce Macrophage Activation by Barnholt, Kimberly E, Kota, Rama S, Aung, Hnin Hnin, Rutledge, John C

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