Search Results - "Barnett, Anthony"
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Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus
Published in Nature reviews. Endocrinology (01-10-2016)“…Key Points Greater understanding of the complex and multifactorial pathogenesis of type 2 diabetes mellitus (T2DM) has informed the development of several new…”
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Type 2 diabetes in adolescents and young adults
Published in The lancet. Diabetes & endocrinology (01-01-2018)“…The prevalence of type 2 diabetes in adolescents and young adults is dramatically increasing. Similar to older-onset type 2 diabetes, the major predisposing…”
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Management of type 2 diabetes: new and future developments in treatment
Published in The Lancet (British edition) (09-07-2011)“…Summary The increasing prevalence, variable pathogenesis, progressive natural history, and complications of type 2 diabetes emphasise the urgent need for new…”
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Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments
Published in Drugs (New York, N.Y.) (01-04-2020)“…Increased hepatic glucose output, the primary liver dysregulation associated with Type 2 diabetes mellitus (T2DM), is not directly or effectively targeted by…”
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Neural imaginaries at work: Exploring Australian addiction treatment providers’ selective representations of the brain in clinical practice
Published in Social science & medicine (1982) (01-06-2020)“…Although addiction neuroscience hopes to uncover the neural basis of addiction and deliver a wide range of novel neuro-interventions to improve the treatment…”
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Efficacy and safety of empagliflozin added to existing antidiabetes treatment in patients with type 2 diabetes and chronic kidney disease: a randomised, double-blind, placebo-controlled trial
Published in The lancet. Diabetes & endocrinology (01-05-2014)“…Summary Background Diabetes is a leading cause of chronic kidney disease (CKD) worldwide. Optimum glycaemic control in patients with type 2 diabetes is…”
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Built environmental correlates of older adults' total physical activity and walking: a systematic review and meta-analysis
Published in The international journal of behavioral nutrition and physical activity (07-08-2017)“…Identifying attributes of the built environment associated with health-enhancing levels of physical activity (PA) in older adults (≥65 years old) has the…”
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SGLT inhibitors in management of diabetes
Published in The lancet. Diabetes & endocrinology (01-10-2013)“…Summary The two main sodium–glucose cotransporters (SGLTs), SGLT1 and SGLT2, provide new therapeutic targets to reduce hyperglycaemia in patients with…”
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Insulin icodec: evolution or revolution in diabetes therapy?
Published in The lancet. Diabetes & endocrinology (01-06-2023)Get full text
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Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin
Published in Current medical research and opinion (01-04-2012)“…Abstract Objective: To evaluate efficacy and safety of saxagliptin as add-on therapy in patients with type 2 diabetes (T2D) with inadequate glycemic control on…”
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Linagliptin for patients aged 70 years or older with type 2 diabetes inadequately controlled with common antidiabetes treatments: a randomised, double-blind, placebo-controlled trial
Published in The Lancet (British edition) (26-10-2013)“…Summary Background A substantial proportion of patients with type 2 diabetes are elderly (≥65 years) but this group has been largely excluded from clinical…”
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Once-weekly albiglutide versus once-daily liraglutide in patients with type 2 diabetes inadequately controlled on oral drugs (HARMONY 7): a randomised, open-label, multicentre, non-inferiority phase 3 study
Published in The lancet. Diabetes & endocrinology (01-04-2014)“…Summary Background As new members of a drug class are developed, head-to-head trials are an important strategy to guide personalised treatment decisions. We…”
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Ultra-long-acting insulin: a new chapter in diabetes therapy?
Published in The lancet. Diabetes & endocrinology (01-11-2024)Get full text
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Future challenges and therapeutic opportunities in type 2 diabetes: Changing the paradigm of current therapy
Published in Diabetes, obesity & metabolism (01-10-2017)“…Most algorithms for type 2 diabetes mellitus (T2DM) do not recommend treatment escalation until glycated haemoglobin (HbA1c) fails to reach the recommended…”
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Obstructive Sleep Apnea and Retinopathy in Patients with Type 2 Diabetes. A Longitudinal Study
Published in American journal of respiratory and critical care medicine (01-10-2017)“…Obstructive sleep apnea (OSA) is associated with several pathophysiological deficits found in diabetic retinopathy (DR). Hence, it's plausible that OSA could…”
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Adherence patterns in patients with type 2 diabetes on basal insulin analogues: missed, mistimed and reduced doses
Published in Current medical research and opinion (01-12-2012)“…Abstract Objective: To describe basal insulin analogue dosing irregularities, the effect of these events on patient functioning, well-being and diabetes…”
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Future glucose-lowering drugs for type 2 diabetes
Published in The lancet. Diabetes & endocrinology (01-04-2016)“…Summary The multivariable and progressive natural history of type 2 diabetes limits the effectiveness of available glucose-lowering drugs. Constraints imposed…”
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SGLT2 inhibitors in older adults: overcoming the age barrier
Published in The Lancet. Healthy longevity (01-04-2023)Get full text
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Drug and alcohol treatment providers’ views about the disease model of addiction and its impact on clinical practice: A systematic review
Published in Drug and alcohol review (01-09-2018)“…Issues Addiction treatment providers’ views about the disease model of addiction (DMA), and their contemporary views about the brain disease model of addiction…”
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Glycaemic control in type 2 diabetes: targets and new therapies
Published in Pharmacology & therapeutics (Oxford) (01-02-2010)“…Type 2 diabetes mellitus (T2DM) is a worldwide public health challenge. Despite the availability of many antidiabetes agents and pharmacotherapies targeting…”
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