Search Results - "Barnes, William G."

Structure-guided combination therapy to potently improve the function of mutant CFTRs by Veit, Guido, Xu, Haijin, Dreano, Elise, Avramescu, Radu G., Bagdany, Miklos, Beitel, Lenore K., Roldan, Ariel, Hancock, Mark A., Lay, Cecilia, Li, Wei, Morin, Katelin, Gao, Sandra, Mak, Puiying A., Ainscow, Edward, Orth, Anthony P., McNamara, Peter, Edelman, Aleksander, Frenkiel, Saul, Matouk, Elias, Sermet-Gaudelus, Isabelle, Barnes, William G., Lukacs, Gergely L.

“…Available corrector drugs are unable to effectively rescue the folding defects of CFTR-ΔF508 (or CFTR-F508del), the most common disease-causing mutation of…”
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Membrane‐bound histamine N‐methyltransferase in mouse brain: possible role in the synaptic inactivation of neuronal histamine by Barnes, William G., Hough, Lindsay B.

“…In the CNS, histamine is a neurotransmitter that is inactivated by histamine N‐methyltransferase (HNMT), a soluble enzyme localized to the cytosol of neurons…”
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G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics by Violin, Jonathan D., DeWire, Scott M., Barnes, William G., Lefkowitz, Robert J.

“…Receptor desensitization progressively limits responsiveness of cells to chronically applied stimuli. Desensitization in the continuous presence of agonist has…”
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Characterization of a new mRNA species from the human histamine N-methyltransferase gene by Barnes, William G, Grinde, Ellinor, Crawford, Dana R, Herrick-Davis, Katharine, Hough, Lindsay B

“…Histamine N-methyltransferase (HNMT), a cytosolic histamine-metabolizing enzyme, is the only known product of the 50-kb human HNMT. Here, a detailed…”
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Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis by Hunton, Dacia L, Barnes, William G, Kim, Jihee, Ren, Xiu-Rong, Violin, Jonathan D, Reiter, Eric, Milligan, Graeme, Patel, Dhavalkumar D, Lefkowitz, Robert J

“…Chemotaxis is a cellular response that directs cell migration toward a chemical gradient and is fundamental to a variety of cellular processes. The receptors…”
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Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2 by Wei, Huijun, Ahn, Seungkirl, Barnes, William G, Lefkowitz, Robert J

“…Binding of beta-arrestins to seven-membrane-spanning receptors (7MSRs) not only leads to receptor desensitization and endocytosis but also elicits additional…”
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Epidemiologic evidence for a causal relation between vaccination and fibrosarcoma tumorigenesis in cats by Kass, P H, Barnes, Jr, W G, Spangler, W L, Chomel, B B, Culbertson, M R

“…Within the past 2 years, a putative causal relationship has been reported between vaccination against rabies and the development of fibrosarcomas at injection…”
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β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation by Barnes, William G., Reiter, Eric, Violin, Jonathan D., Ren, Xiu-Rong, Milligan, Graeme, Lefkowitz, Robert J.

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Characteristics of coagulase-negative staphylococci from infants with bacteremia by Hall, R T, Hall, S L, Barnes, W G, Izuegbu, J, Rogolsky, M, Zorbas, I

“…Twenty-nine infants were identified as having coagulase-negative staphylococcal (C-S) bacteremia. Fourteen infants had pneumonia and 10 had central…”
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Enzymatic Modification of Glycocalyx in the Treatment of Experimental Endocarditis Due to Viridans Streptococci by Dall, Lawrence, Barnes, William G., Lane, James W., Mills, John

“…The presence of abundant surface polysaccharide, or glycocalyx, on viridans streptococci has been associated with failureto eradicate the organism from…”
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The emergency department diagnosis of Trichomonas vaginitis by Bennett, J R, Barnes, W G, Coffman, S

“…Trichomonas vaginalis is a common cause of vaginitis in emergency department patient populations. While the diagnosis of this condition is usually on the basis…”
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G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics by Jonathan D. Violin, Scott M. DeWire, William G. Barnes, Robert J. Lefkowitz

“…Receptor desensitization progressively limits responsiveness of cells to chronically applied stimuli. Desensitization in the continuous presence of agonist has…”
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G Protein-coupled Receptor Kinase and beta -Arrestin-mediated Desensitization of the Angiotensin II Type 1 sub(A) Receptor Elucidated by Diacylglycerol Dynamics by Violin, Jonathan D, DeWire, Scott M, Barnes, William G, Lefkowitz, Robert J

“…Receptor desensitization progressively limits responsiveness of cells to chronically applied stimuli. Desensitization in the continuous presence of agonist has…”
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Stable Interaction between β-Arrestin 2 and Angiotensin Type 1A Receptor Is Required for β-Arrestin 2-mediated Activation of Extracellular Signal-regulated Kinases 1 and 2 by Huijun Wei, Seungkirl Ahn, William G. Barnes, Robert J. Lefkowitz

“…Binding of β-arrestins to seven-membrane-spanning receptors (7MSRs) not only leads to receptor desensitization and endocytosis but also elicits additional…”
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Urethral and endocervical culturing: gonorrhea and chlamydia by McNabney, W K, Barnes, W G

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beta -Arrestin 1 and G sub(alphaq/11) Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation by Barnes, William G, Reiter, Eric, Violin, Jonathan D, Ren, Xiu-Rong, Milligan, Graeme, Lefkowitz, Robert J

“…beta -Arrestins were initially shown, in conjunction with G protein-coupled receptor kinases, to be involved in the desensitization and internalization of…”
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β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation by William G. Barnes, Eric Reiter, Jonathan D. Violin, Xiu-Rong Ren, Graeme Milligan, Robert J. Lefkowitz

“…β-Arrestins were initially shown, in conjunction with G protein-coupled receptor kinases, to be involved in the desensitization and internalization of…”
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beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation by Barnes, William G, Reiter, Eric, Violin, Jonathan D, Ren, Xiu-Rong, Milligan, Graeme, Lefkowitz, Robert J

“…beta-Arrestins were initially shown, in conjunction with G protein-coupled receptor kinases, to be involved in the desensitization and internalization of…”
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Molecular analyses of conjugative, gentamicin-resistance plasmids from staphylococcal clinical isolates by Zorbas, I, Hall, R T, Hall, S L, Barnes, W G, Rogolsky, M

“…Gentamicin-resistant Staphylococcus aureus and Staphylococcus epidermidis strains which were isolated from infants with staphylococcal bacteremia were analyzed…”
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Complications With Heparin-Lock Needles by Couchonnal, Guillermo J, Hodges, Glenn R, Barnes, William G, Elmets, Craig A, Clark, Gary M

“…The incidence of phlebitis was determined for heparin-lock needles after use of three different methods of skin preparation and follow-up care. Phlebitis was…”
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