Search Results - "Barnes, Frank L."
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Using outcome data from one thousand mosaic embryo transfers to formulate an embryo ranking system for clinical use
Published in Fertility and sterility (01-05-2021)“…To study how the attributes of mosaicism identified during preimplantation genetic testing for aneuploidy relate to clinical outcomes, in order to formulate a…”
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Accurate quantitation of mitochondrial DNA reveals uniform levels in human blastocysts irrespective of ploidy, age, or implantation potential
Published in Fertility and sterility (01-01-2017)“…Objective To accurately determine mitochondrial DNA (mtDNA) levels in human blastocysts. Design Retrospective analysis. Setting IVF clinic. Patient(s) A total…”
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SARS-CoV-2 can infect human embryos
Published in Scientific reports (14-09-2022)“…The spread of SARS-CoV-2 has led to a devastating pandemic, with infections resulting in a range of symptoms collectively known as COVID-19. The full…”
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Assessment of aneuploidy concordance between clinical trophectoderm biopsy and blastocyst
Published in Human reproduction (Oxford) (01-01-2019)Get full text
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One hundred mosaic embryos transferred prospectively in a single clinic: exploring when and why they result in healthy pregnancies
Published in Fertility and sterility (01-02-2019)“…To investigate the parameters of mosaicism and the biological mechanisms leading to healthy pregnancies from mosaic embryo transfers. Prospective study. IVF…”
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Assessment of aneuploidy concordance between clinical trophectoderm biopsy and blastocyst
Published in Human reproduction (Oxford) (01-01-2019)“…Abstract STUDY QUESTION Is a clinical trophectoderm (TE) biopsy a suitable predictor of chromosomal aneuploidy in blastocysts? SUMMARY ANSWER In the analyzed…”
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Haplotype-aware inference of human chromosome abnormalities
Published in Proceedings of the National Academy of Sciences - PNAS (16-11-2021)“…Extra or missing chromosomes—a phenomenon termed aneuploidy—frequently arise during human meiosis and embryonic mitosis and are the leading cause of pregnancy…”
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Let the data do the talking: the need to consider mosaicism during embryo selection
Published in Fertility and sterility (01-11-2021)“…Chromosomal mosaicism, the coexistence of cells with different chromosomal content, has been documented in human embryos for 3 decades. Early versions of…”
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Chromosomal, gestational, and neonatal outcomes of embryos classified as a mosaic by preimplantation genetic testing for aneuploidy
Published in Fertility and sterility (01-11-2023)“…To understand the clinical risks associated with the transfer of embryos classified as a mosaic using preimplantation genetic testing for aneuploidy. Analysis…”
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Mitochondrial DNA quantitation—making sense of contradictory reports
Published in Human reproduction (Oxford) (01-10-2017)Get full text
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Is mitochondrial DNA quantitation in blastocyst trophectoderm cells predictive of developmental competence and outcome in clinical IVF?
Published in Journal of assisted reproduction and genetics (01-12-2017)“…Behind every successful IVF embryo transfer, there is a great game of chance. Methods seeking to tilt the balance and increase the likelihood of implantation…”
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Accurate Quantitation of Mitochondrial DNA Reveals Uniform Levels in Human Blastocysts Irrespective of Ploidy, Age, or Implantation Potential
Published in Obstetrical & gynecological survey (01-04-2017)“…(Abstracted from Fertil Steril 2017;107:34–42)Changes in mitochondrial DNA (mtDNA) copy number correlate with several conditions, including aging, myopathies,…”
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Differential Display and Suppressive Subtractive Hybridization Used to Identify Granulosa Cell Messenger RNA Associated with Bovine Oocyte Developmental Competence
Published in Biology of reproduction (01-06-2001)“…The main objective of this study was to identify mRNA expressed in the granulosa cells characterizing differentiated follicles bearing developmentally…”
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Subtractive hybridization used to identify mRNA associated with the maturation of bovine oocytes
Published in Molecular reproduction and development (01-10-2000)“…The main objective of this project is to identify mRNA associated with oocyte maturation and embryonic developmental competency. The knowledge of genes and…”
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Nuclear transplantation by microinjection of inner cell mass and granulosa cell nuclei
Published in Molecular reproduction and development (01-07-1994)“…The developmental potential of bovine inner cell mass (ICM) and somatic differentiated (granulosa cell) nuclei was investigated using nuclear transplantation…”
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Differential Display and Suppressive Subtractive Hybridization Used to Identify Granulosa Cell Messenger RNA Associated with Bovine Oocyte Developmental Competence1
Published in Biology of reproduction (01-06-2001)“…The main objective of this study was to identify mRNA expressed in the granulosa cells characterizing differentiated follicles bearing developmentally…”
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Histone H1 kinase activity in bovine oocytes following calcium stimulation
Published in Molecular reproduction and development (01-02-1993)“…The influence of number of Ca2+ stimulations on the profile of histone H1 kinase activity in bovine oocytes was investigated. A CA2+ stimulation consisted of…”
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Electrically induced calcium elevation, activation, and parthenogenetic development of bovine oocytes
Published in Molecular reproduction and development (01-02-1993)“…The influence of electrical stimulation on the level of intracellular Ca2+ in bovine oocytes, as well as activation and extent of parthenogenetic development,…”
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Chromosomal, Gestational, and Neonatal Outcomes of Embryos Classified as a Mosaic by Preimplantation Genetic Testing for Aneuploidy
Published in Obstetrical & gynecological survey (01-02-2024)“…(Abstracted from Fertil Steril 2023;120(5):957) Chromosomal segregation errors during mitosis can result in embryonic mosaicism, a phenomenon where different…”
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THE EFFECT OF EMBRYO MORPHOLOGY AND CULTURING METHODS ON THE PERFORMANCE OF NON-INVASIVE PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDIES
Published in Fertility and sterility (01-09-2021)Get full text
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