Search Results - "Barnes, Carmen M"

Natural variations in AAVHSC16 significantly reduce liver tropism and maintain broad distribution to periphery and CNS by Smith, Laura J., Schulman, Lindsay A., Smith, Samantha, Van Lieshout, Laura, Barnes, Carmen M., Behmoiras, Liana, Scarpitti, Meghan, Kivaa, Monicah, Duong, Khanh L., Benard, Ludo O., Ellsworth, Jeff L., Avila, Nancy, Faulkner, Deiby, Hayes, April, Lotterhand, Jason, Rivas, Jose Israel, Sengooba, Arnold V., Tzianabos, Alec, Seymour, Albert B., Francone, Omar L.

“…Adeno-associated viruses derived from human hematopoietic stem cells (AAVHSCs) are naturally occurring AAVs. Fifteen AAVHSCs have demonstrated broad…”
Get full text

Maternal Preeclampsia Predicts the Development of Bronchopulmonary Dysplasia by Hansen, Anne R., MD, MPH, Barnés, Carmen M., PhD, Folkman, Judah, MD, McElrath, Thomas F., MD, PhD

“…Objective To test the hypothesis that exposure to preeclampsia is associated with an increased risk of bronchopulmonary dysplasia (BPD). Study design A…”
Get full text

Correlation of 2-Methoxyestradiol Levels in Cord Blood and Complications of Prematurity by Barnes, Carmen M, McElrath, Thomas F, Folkman, Judah, Hansen, Anne R

“…2-methoxyestradiol (2ME2) is a potent antiangiogenic molecule that inhibits the expression of hypoxia-inducible factor (HIF)-1α and, consequently, of VEGF and…”
Get full text

PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition by Panigrahy, Dipak, Kaipainen, Arja, Huang, Sui, Butterfield, Catherine E, Barnés, Carmen M, Fannon, Michael, Laforme, Andrea M, Chaponis, Deviney M, Folkman, Judah, Kieran, Mark W

“…Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have demonstrated recently that…”
Get full text

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice by Panigrahy, Dipak, Edin, Matthew L, Lee, Craig R, Huang, Sui, Bielenberg, Diane R, Butterfield, Catherine E, Barnés, Carmen M, Mammoto, Akiko, Mammoto, Tadanori, Luria, Ayala, Benny, Ofra, Chaponis, Deviney M, Dudley, Andrew C, Greene, Emily R, Vergilio, Jo-Anne, Pietramaggiori, Giorgio, Scherer-Pietramaggiori, Sandra S, Short, Sarah M, Seth, Meetu, Lih, Fred B, Tomer, Kenneth B, Yang, Jun, Schwendener, Reto A, Hammock, Bruce D, Falck, John R, Manthati, Vijaya L, Ingber, Donald E, Kaipainen, Arja, D'Amore, Patricia A, Kieran, Mark W, Zeldin, Darryl C

“…Epoxyeicosatrienoic acids (EETs) are small molecules produced by cytochrome P450 epoxygenases. They are lipid mediators that act as autocrine or paracrine…”
Get full text

Conjugated Platinum(IV)−Peptide Complexes for Targeting Angiogenic Tumor Vasculature by Mukhopadhyay, Sumitra, Barnés, Carmen M, Haskel, Ariel, Short, Sarah M, Barnes, Katie R, Lippard, Stephen J

“…The integrins αvβ3 and αvβ5 and the membrane-spanning surface protein aminopeptidase N (APN) are highly expressed in tumor-induced angiogenesis, making them…”
Get full text

Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature by Khan, Omar F, Zaia, Edmond W, Jhunjhunwala, Siddharth, Xue, Wen, Cai, Wenxin, Yun, Dong Soo, Barnes, Carmen M, Dahlman, James E, Dong, Yizhou, Pelet, Jeisa M, Webber, Matthew J, Tsosie, Jonathan K, Jacks, Tyler E, Langer, Robert, Anderson, Daniel G

“…Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that involve inflammation, such as chronic asthma and obstructive…”
Get full text

Evidence by Molecular Profiling for a Placental Origin of Infantile Hemangioma by Barnés, Carmen M., Huang, Sui, Kaipainen, Arja, Sanoudou, Despina, Chen, Emy J., Gabriel S. Eichler, Yuchun Guo, Yu, Ying, Ingber, Donald E., Mulliken, John B., Beggs, Alan H., Folkman, Judah, Steven J. Fishman

“…The origin of the pathogenic endothelial cells in common infantile hemangioma is unknown. We show here that the transcriptomes of human placenta and infantile…”
Get full text

Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib by Barnés, Carmen M., Prox, Daniela, Christison-Lagay, Emily A., Le, Hau D., Short, Sarah, Cassiola, Flavia, Panigrahy, Dipak, Chaponis, Deviney, Butterfield, Catherine, Nehra, Deepika, Fallon, Erica M., Kieran, Mark, Folkman, Judah, Puder, Mark

“…Introduction: We investigated the use of dietary omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) in the treatment of neuroblastoma both as a sole agent and…”
Get full text

Generation of multiple angiogenesis inhibitors by human pancreatic cancer by KISKER, Oliver, ONIZUKA, Shinya, BANYARD, Jacqueline, KOMIYAMA, Tomoko, BECKER, Christian M, ACHILLES, Eike Gert, BARNES, Carmen M, O'REILLY, Michael S, FOLKMAN, Judah, PIRIE-SHEPHERD, Steven R

“…A primary inoculum of human pancreatic cancer cells (BxPC-3) has the ability to inhibit the growth of a secondary tumor in an in vivo animal model. Such…”
Get full text

Structural and Kinetic Studies of a Cisplatin-modified DNA Icosamer Binding to HMG1 Domain B by Jamieson, E R, Jacobson, M P, Barnes, C M, Chow, C S, Lippard, S J

“…The high mobility group (HMG) domain is a DNA-binding motif found in the non-histone chromosomal proteins, HMG1 and HMG2, and some transcription factors…”
Get full text

The placenta as a cell source in fetal tissue engineering by Kaviani, Amir, Perry, Tjörvi E., Barnes, Carmen M., Oh, Jung-Tak, Ziegler, Moritz M., Fishman, Steven J., Fauza, Dario O.

“…Purpose: This study was aimed at determining whether fetal tissue constructs can be engineered from cells derived from the placenta. Methods: A subpopulation…”
Get full text

A Single HMG Domain in High-Mobility Group 1 Protein Binds to DNAs as Small as 20 Base Pairs Containing the Major Cisplatin Adduct by Chow, Christine S, Barnes, Carmen M, Lippard, Stephen J

“…Proteins containing a relatively new DNA-binding motif known as the high-mobility group (HMG) domain bind specifically to DNA modified by the anticancer drug…”
Get full text

Iron Uptake in Ferritin is Blocked by Binding of [Cr(TREN)(H2O)(OH)]2+, A Slow Dissociating Model for [Fe(H2O)6]2 by Barnés, Carmen M., Theil, Elizabeth C., Raymond, Kenneth N.

“…Ferritin concentrates iron as a hydrous ferric oxide in a protein cavity (8 nm in diameter) by using eight pores along the threefold symmetry axes of the…”
Get full text

The placenta theory and the origin of infantile hemangioma by Barnés, Carmen M, Christison-Lagay, Emily A, Folkman, Judah

“…The pathogenesis of infantile hemangioma is unknown. In recent years, much of the focus has been placed at identifying the cell type(s) responsible for tumor…”
Get more information

Iron uptake in ferritin is blocked by binding of [Cr(TREN)(H(2)O)(OH)](2+), a slow dissociating model for [Fe(H(2)O)(6)](2+) by Barnés, Carmen M, Theil, Elizabeth C, Raymond, Kenneth N

“…Ferritin concentrates iron as a hydrous ferric oxide in a protein cavity (8 nm in diameter) by using eight pores along the threefold symmetry axes of the…”
Get full text

Competition studies in horse spleen ferritin probed by a kinetically inert inhibitor, [Cr(TREN)(H(2)O)(OH)](2+), and a highly luminescent Tb(III) reagent by Barnés, Carmen M, Petoud, Stéphane, Cohen, Seth M, Raymond, Kenneth N

“…The ability of ferritin as an Fe(II) detoxifier and Fe(III) storage protein is limited by its ability to recognize and incorporate Fe(II), which is then…”
Get full text

Competition studies in horse spleen ferritin probed by a kinetically inert inhibitor, [Cr(TREN)(H2O)(OH)]2+, and a highly luminescent Tb(III) reagent by Barnés, Carmen M., Petoud, Stéphane, Cohen, Seth M., Raymond, Kenneth N.

“…The ability of ferritin as an Fe(II) detoxifier and Fe(III) storage protein is limited by its ability to recognize and incorporate Fe(II), which is then…”
Get full text

PPAR[alpha] agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition by Panigrahy, Dipak, Kaipainen, Arja, Huang, Sui, Butterfield, Catherine E, Barnés, Carmen M, Fannon, Michael, Laforme, Andrea M, Chaponis, Deviney M, Folkman, Judah, Kieran, Mark W

“…Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have demonstrated recently that…”
Get full text

The placenta as a cell source in fetal tissue engineering. Discussion by KAVIANI, Amir, PERRY, Tjörvi E, BARNES, Carmen M, OH, Jung-Tak, ZIEGLER, Moritz M, FISHMAN, Steven J, FAUZA, Dario O, FELTIS, LAQUAGLIA

Get full text