Search Results - "Barneh, Farnaz"

Bipartite network models to design combination therapies in acute myeloid leukaemia by Jafari, Mohieddin, Mirzaie, Mehdi, Bao, Jie, Barneh, Farnaz, Zheng, Shuyu, Eriksson, Johanna, Heckman, Caroline A., Tang, Jing

“…Combination therapy is preferred over single-targeted monotherapies for cancer treatment due to its efficiency and safety. However, identifying effective drug…”
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RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia by Grinev, Vasily V., Barneh, Farnaz, Ilyushonak, Ilya M., Nakjang, Sirintra, Smink, Job, van Oort, Anita, Clough, Richard, Seyani, Michael, McNeill, Hesta, Reza, Mojgan, Martinez-Soria, Natalia, Assi, Salam A., Ramanouskaya, Tatsiana V., Bonifer, Constanze, Heidenreich, Olaf

“…The fusion oncogene RUNX1/RUNX1T1 encodes an aberrant transcription factor, which plays a key role in the initiation and maintenance of acute myeloid leukemia…”
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Repurposing CD19-directed immunotherapies for pediatric t(8;21) acute myeloid leukemia by Barneh, Farnaz, Koedijk, Joost B, Wijnen, Noa E, Meulendijks, Tom, Ashtiani, Minoo, Dunnebach, Ester, Dautzenberg, Noël, Cornel, Annelisa M, Krippner-Heidenreich, Anja, Klein, Kim, Zwaan, Michel C, Kuball, Jürgen, Nierkens, Stefan, Cloos, Jacqueline, Kaspers, Gertjan J L, Heidenreich, Olaf

“…Not available.Not available…”
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t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming by Kellaway, Sophie, Chin, Paulynn S, Barneh, Farnaz, Bonifer, Constanze, Heidenreich, Olaf

“…Acute myeloid leukemia (AML) is a heterogenous disease with multiple sub-types which are defined by different somatic mutations that cause blood cell…”
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P437: EFFECTIVE IMMUNOTHERAPY OF PEDIATRIC T(8;21) ACUTE MYELOID LEUKEMIA BY REPURPOSING CD3XCD19 TARGETING BISPECIFIC ANTIBODIES by Wijnen, Noa, Barneh, Farnaz, Meulendijks, Thomas, Klein, Kim, Duddebach, Ester, Cornel, Annelisa, Dautzenberg, Noël, Ashtiani, Minoo, Krippner‐Heidenreich, Anja, Nierkens, Stefan, Heidenreich, Olaf, Kaspers, Gertjan

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Two Novel Tri-Aryl Derivatives Attenuate the Invasion-Promoting Effects of Stromal Mesenchymal Stem Cells on Breast Cancer by Moradi, Khadijeh, Barneh, Farnaz, Irian, Saeed, Amini, Mohsen, Moradpoor, Raheleh, Amanzadeh, Amir, Choopani, Samira, Rahimi, Hamzeh, Ghodselahi, Tayebeh, Boujar, Massoud M, Salimi, Mona

“…The concept of Epithelial-Mesenchymal Transition (EMT) to promote carcinoma progression has been recognized as a venue for research on novel anticancer drugs…”
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EphB4 Tyrosine Kinase Stimulation Inhibits Growth of MDA-MB-231 Breast Cancer Cells in a Dose and Time Dependent Manner by Sabzghabaee, A. M., Haghjooy-Javanmard, Shaghayegh, Mirmohammadsadeghi, Hamid, Moshayedi, Mona, Barneh, Farnaz, Badri, Shirinsadat

“…Background. EphB4 receptor tyrosine kinase is of diagnostic and therapeutic value due to its overexpression in breast tumors. Dual functions of tumor promotion…”
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Fabrication and characterization of biodegradable polymeric films as a corneal stroma substitute by Salehi, Sahar, Fathi, Mohammadhossein, Javanmard, Shaghayegh Haghjooy, Barneh, Farnaz, Moshayedi, Mona

“…Biodegradable elastomeric materials such as poly glycerol sebacate (PGS) have gained much current attention in the field of soft tissue engineering. The…”
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Updates on drug-target network; facilitating polypharmacology and data integration by growth of DrugBank database by Barneh, Farnaz, Jafari, Mohieddin, Mirzaie, Mehdi

“…Network pharmacology elucidates the relationship between drugs and targets. As the identified targets for each drug increases, the corresponding drug-target…”
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Rigosertib potently protects against colitis-associated intestinal fibrosis and inflammation by regulating PI3K/AKT and NF-κB signaling pathways by Rahmani, Farzad, Asgharzadeh, Fereshteh, Avan, Amir, Barneh, Farnaz, Parizadeh, Mohammad Reza, Ferns, Gordon A., Ryzhikov, Mikhail, Ahmadian, Mohammad Reza, Giovannetti, Elisa, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi

“…Rigosertib (RGS) is a PI3K inhibitor that exerts protective effects against tumor progression and cancer-related inflammation. This study was aimed to explore…”
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Testis-Specific Y‑Centric Protein–Protein Interaction Network Provides Clues to the Etiology of Severe Spermatogenic Failure by Ansari-Pour, Naser, Razaghi-Moghadam, Zahra, Barneh, Farnaz, Jafari, Mohieddin

“…Pinpointing causal genes for spermatogenic failure (SpF) on the Y chromosome has been an ever daunting challenge with setbacks during the past decade. Since…”
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A RUNX1/ETO-SKP2-CDKN1B axis regulates expression of telomerase in t (8;21) acute myeloid leukemia by Moses, Emmanuel J., Azlan, Adam, Khor, Kang Zi, Mot, Yee Yik, Mohamed, Saleem, Seeni, Azman, Barneh, Farnaz, Heidenreich, Olaf, Yusoff, Narazah

“…The fusion oncoprotein RUNX1/ETO which results from the chromosomal translocation t (8;21) in acute myeloid leukemia (AML) is an essential driver of leukemic…”
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Valproic acid inhibits the protective effects of stromal cells against chemotherapy in breast cancer: Insights from proteomics and systems biology by Barneh, Farnaz, Salimi, Mona, Goshadrou, Fatemeh, Ashtiani, Minoo, Mirzaie, Mehdi, Zali, Hakimeh, Jafari, Mohieddin

“…Interaction between tumor and stromal cells is beginning to be decoded as a contributor to chemotherapy resistance. Here, we aim to take a system‐level…”
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Integrated use of bioinformatic resources reveals that co-targeting of histone deacetylases, IKBK and SRC inhibits epithelial-mesenchymal transition in cancer by Barneh, Farnaz, Mirzaie, Mehdi, Nickchi, Payman, Tan, Tuan Zea, Thiery, Jean Paul, Piran, Mehran, Salimi, Mona, Goshadrou, Fatemeh, Aref, Amir R, Jafari, Mohieddin

“…Abstract With the advent of high-throughput technologies leading to big data generation, increasing number of gene signatures are being published to predict…”
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Rigosertib elicits potent anti-tumor responses in colorectal cancer by inhibiting Ras signaling pathway by Rahmani, Farzad, Hashemzehi, Milad, Avan, Amir, Barneh, Farnaz, Asgharzadeh, Fereshteh, Moradi Marjaneh, Reyhaneh, Soleimani, Atena, Parizadeh, Mohammadreza, Ferns, Gordon A., Ghayour Mobarhan, Majid, Ryzhikov, Mikhail, Afshari, Amir Reza, Ahmadian, Mohammad Reza, Giovannetti, Elisa, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi

“…The therapeutic potency of Rigosertib (RGS) in the treatment of the myelodysplastic syndrome has been investigated previously, but little is known about its…”
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A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia by Koedijk, Joost B., van der Werf, Inge, Penter, Livius, Vermeulen, Marijn A., Barneh, Farnaz, Perzolli, Alicia, Meesters-Ensing, Joyce I., Metselaar, Dennis S., Margaritis, Thanasis, Fiocco, Marta, de Groot-Kruseman, Hester A., Moeniralam, Rubina, Bang Christensen, Kristina, Porter, Billie, Pfaff, Kathleen, Garcia, Jacqueline S., Rodig, Scott J., Wu, Catherine J., Hasle, Henrik, Nierkens, Stefan, Belderbos, Mirjam E., Zwaan, C. Michel, Heidenreich, Olaf

“…Because of the low mutational burden and consequently, fewer potential neoantigens, children with acute myeloid leukemia (AML) are thought to have a T…”
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Metformin inhibits polyphosphate-induced hyper-permeability and inflammation by Asgharzadeh, Fereshteh, Barneh, Farnaz, Fakhraie, Maryam, Adel barkhordar, Seyede leili, Shabani, Mohammad, Soleimani, Atena, Rahmani, Farzad, Ariakia, Fatemeh, Mehraban, Saeedeh, Avan, Amir, Hashemzehi, Milad, Arjmand, Mohammad-Hassan, Behnam-Rassouli, Reyhaneh, Jaberi, Najmeh, Sayyed-Hosseinian, Sayyed-Hadi, Ferns, Gordon A, Ryzhikov, Mikhail, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi

“…•PolyP induce inflammatory responses through mTOR pathway in endothelial cells.•PolyP disrupts endothelial barrier integrity in Vital organs.•Metformin…”
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Intraperitoneal Administration of Telmisartan Prevents Postsurgical Adhesion Band Formation by Arjmand, Mohammad-Hassan, Zahedi-Avval, Farnaz, Barneh, Farnaz, Mousavi, Seyed Hadi, Asgharzadeh, Fereshteh, Hashemzehi, Milad, Soleimani, Atena, Avan, Amir, Fakhraie, Maryam, Nasiri, Seyedeh Najibeh, Mehraban, Saeedeh, Ferns, Gordon A., Ryzhikov, Mikhail, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi

“…Angiotensin II receptor blockers (ARBs) have a potential role in reducing inflammation and fibrosis. We have integrated systems and molecular biology…”
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Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer by Hashemzehi, Milad, Rahmani, Farzad, Khoshakhlagh, Mahdieh, Avan, Amir, Asgharzadeh, Fereshteh, Barneh, Farnaz, Moradi-Marjaneh, Reyhaneh, Soleimani, Atena, Fiuji, Hamid, Ferns, Gordon A, Ryzhikov, Mikhail, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi

“…The renin-angiotensin system (RAS) is up-regulated in patients with colorectal cancer (CRC) and is reported to be associated with poor prognosis and…”
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Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 by Cornel, Annelisa M., van der Sman, Loutje, van Dinter, Jip T, Arrabito, Marta, Dunnebach, Ester, van Hoesel, Marliek, Kluiver, Thomas A, Lopes, Ana P, Dautzenberg, Noël M M, Dekker, Linde, van Rijn, Jorik M, van den Beemt, Denise A M H, Buhl, Juliane L, du Chatinier, Aimee, Barneh, Farnaz, Lu, Yuyan, Lo Nigro, Luca, Krippner-Heidenreich, Anja, Sebestyén, Zsolt, Kuball, Jurgen, Hulleman, Esther, Drost, Jarno, van Heesch, Sebastiaan, Heidenreich, Olaf T, Peng, Weng Chuan, Nierkens, Stefan

“…Human leukocyte antigen (HLA) restriction of conventional T-cell targeting introduces complexity in generating T-cell therapy strategies for patients with…”
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