Search Results - "Barnea, Ofer"
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1
Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness
Published in EMBO molecular medicine (05-02-2021)“…Genetic variants account for approximately half the cases of congenital and early‐onset deafness. Methods and technologies for viral delivery of genes into the…”
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2
Mechano-electric feedback effects in a three-dimensional (3D) model of the contracting cardiac ventricle
Published in PloS one (01-01-2018)“…Mechano-electric feedback affects the electrophysiological and mechanical function of the heart and the cellular, tissue, and organ properties. To determine…”
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3
Interactions of brain, blood, and CSF: a novel mathematical model of cerebral edema
Published in Fluids and barriers of the CNS (16-09-2021)“…Previous models of intracranial pressure (ICP) dynamics have not included flow of cerebral interstitial fluid (ISF) and changes in resistance to its flow when…”
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4
Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution
Published in Genome Biology (25-08-2021)“…Nullomers and nullpeptides are short DNA or amino acid sequences that are absent from a genome or proteome, respectively. One potential cause for their absence…”
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5
Reduced changes in protein compared to mRNA levels across non-proliferating tissues
Published in BMC genomics (18-04-2017)“…The quantitative relations between RNA and protein are fundamental to biology and are still not fully understood. Across taxa, it was demonstrated that the…”
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6
Hemorrhage control of liver injury by short electrical pulses
Published in PloS one (08-01-2013)“…Trauma is a leading cause of death among young individuals globally and uncontrolled hemorrhage is the leading cause of preventable death. Controlling…”
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7
DNA methylation dynamics during embryonic development and postnatal maturation of the mouse auditory sensory epithelium
Published in Scientific reports (26-11-2018)“…The inner ear is a complex structure responsible for hearing and balance, and organ pathology is associated with deafness and balance disorders. To evaluate…”
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8
Labor progress indices and dynamics of the individual uterine contraction during the active stage of labor
Published in The journal of obstetrics and gynaecology research (01-03-2014)“…Aim To obtain and study new data on the dynamics of the labor process and to develop a contraction‐based index of labor progress. Methods This study was…”
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9
The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune Cells
Published in PloS one (03-06-2016)“…Interferon Regulatory Factor-8 (IRF-8) serves as a key factor in the hierarchical differentiation towards monocyte/dendritic cell lineages. While much insight…”
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10
Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma
Published in Cell genomics (11-01-2023)“…Epithelial responses to the cytokine interleukin-13 (IL-13) cause airway obstruction in asthma. Here we utilized multiple genomic techniques to identify…”
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11
Relations between fetal head descent and cervical dilatation during individual uterine contractions in the active stage of labor
Published in The journal of obstetrics and gynaecology research (01-08-2009)“…The relationship between instantaneous changes in fetal head station and cervical dilatation within the individual contraction during the active stage of labor…”
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12
0317 Advancing Home Sleep Testing: A Comparative Analysis of Type 2 New HST Technology vs. In-Lab PSG Validation Study
Published in Sleep (New York, N.Y.) (20-04-2024)“…Abstract Introduction Currently, a typical home sleep test only measures respiratory signals, not actual sleep. Therefore, results may be inconclusive or…”
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13
Limitation of cerebral blood flow by increased venous outflow resistance in elevated ICP
Published in Journal of applied physiology (1985) (2024)“…Extensive investigation and modeling efforts have been dedicated to cerebral pressure autoregulation, which is primarily regulated by the ability of the…”
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14
Mechanisms of reduced cerebral blood flow in cerebral edema and elevated intracranial pressure
Published in Journal of applied physiology (1985) (01-02-2023)“…A mechanism of elevated intracranial pressure (ICP) in cerebral edema and its effects on cerebral blood flow (CBF) are presented in this paper. To study and…”
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15
Balancing the circulation: Theoretic optimization of pulmonary/systemic flow ratio in hypoplastic left heart syndrome
Published in Journal of the American College of Cardiology (01-11-1994)“…Objectives. This study examined the effects of the pulmonary (Qp)/systemic (Qs) blood flow ratio (Qp/Qs) on systemic oxygen availability in neonates with…”
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16
330 Interactions of Brain, Blood, and CSF: A Novel Mathematical Model of Cerebral Edema
Published in Neurosurgery (01-04-2023)“…INTRODUCTION: Previous models of intracranial pressure (ICP) dynamics have not included flow of cerebral interstitial fluid (ISF) and changes in resistance to…”
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17
Cerebral blood flow augmentation using a cardiac-gated intracranial pulsating balloon pump in a swine model of elevated ICP
Published in Journal of neurosurgery (01-05-2020)“…Augmenting brain perfusion or reducing intracranial pressure (ICP) dose is the end target of many therapies in the neuro-critical care unit. Many present…”
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18
Intracranial Pulsating Balloon-Based Cardiac-Gated ICP Modulation Impact on Brain Oxygenation: A Proof-of-Concept Study in a Swine Model
Published in Neurocritical care (01-12-2022)“…Background Brain oxygenation improvement is a sought-after goal in neurocritical care patients. Previously, we have shown that cerebral blood flow improvement…”
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19
Mechano-electric feedback effects in a three-dimensional
Published in PloS one (17-01-2018)“…Mechano-electric feedback affects the electrophysiological and mechanical function of the heart and the cellular, tissue, and organ properties. To determine…”
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Journal Article -
20
Cardiac-gated intracranial elastance in a swine model of raised intracranial pressure: a novel method to assess intracranial pressure-volume dynamics
Published in Journal of neurosurgery (01-05-2021)“…Previous studies have demonstrated the importance of intracranial elastance; however, methodological difficulties have limited widespread clinical use…”
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