Search Results - "Barndt, Robert J"

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2 by Shiao, Frank, Liu, Li-Ching O, Huang, Nanxi, Lai, Ying-Jung J, Barndt, Robert J, Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D, Lin, Chen-Yong

“…Mutations of hepatocyte growth factor activator inhibitor (HAI)-2 in humans cause sodium loss in the gastrointestinal (GI) tract in patients with syndromic…”
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Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing by Barndt, Robert J., Ma, Ning, Tang, Ying, Haugh, Michael P., Alamri, Laila S., Chan, Stephen Y., Wu, Haodi

“…As the most common cause of heart failure, dilated cardiomyopathy (DCM) is characterized by dilated ventricles and weakened contractile force. Mutations in the…”
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Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Lamp2 Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease by Barndt, Robert J, Liu, Qing, Tang, Ying, Haugh, Michael P, Cui, Jeffery, Chan, Stephen Y, Wu, Haodi

“…Danon disease (DD) is caused by mutations of the gene encoding lysosomal-associated membrane protein type 2 ( ), which lead to impaired autophagy, glycogen…”
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Targeted deletion of HAI-1 increases prostasin proteolysis but decreases matriptase proteolysis in human keratinocytes by Lu, Dajun D., Gu, Yayun, Li, Sheng-Wen A., Barndt, Robert J., Huang, Shih-Ming, Wang, Jehng-Kang, Su, Hui Chen, Johnson, Michael D., Lin, Chen-Yong

“…Epidermal differentiation and barrier function require well-controlled matriptase and prostasin proteolysis, in which the Kunitz-type serine protease inhibitor…”
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Imbalanced Matriptase Pericellular Proteolysis Contributes to the Pathogenesis of Malignant B-Cell Lymphomas by Chou, Feng-Pai, Chen, Ya-Wen, Zhao, Xianfeng F, Xu-Monette, Zijun Y, Young, Ken H, Gartenhaus, Ronald B, Wang, Jehng-Kang, Kataoka, Hiroaki, Zuo, Annie H, Barndt, Robert J, Johnson, Michael, Lin, Chen-Yong

“…Membrane-associated serine protease matriptase is widely expressed by epithelial/carcinoma cells in which its proteolytic activity is tightly controlled by the…”
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Previously Uncharacterized Histone Acetyltransferases Implicated in Mammalian Spermatogenesis by Lahn, Bruce T., Tang, Zhao Lan, Zhou, Jianxin, Barndt, Robert J., Parvinen, Martti, Allis, C. David, Page, David C.

“…During spermiogenesis (the maturation of spermatids into spermatozoa) in many vertebrate species, protamines replace histones to become the primary…”
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Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension by Tai, Yi-Yin, Yu, Qiujun, Tang, Ying, Sun, Wei, Kelly, Neil J, Okawa, Satoshi, Zhao, Jingsi, Schwantes-An, Tae-Hwi, Lacoux, Caroline, Torrino, Stephanie, Al Aaraj, Yassmin, El Khoury, Wadih, Negi, Vinny, Liu, Mingjun, Corey, Catherine G, Belmonte, Frances, Vargas, Sara O, Schwartz, Brian, Bhat, Bal, Chau, B Nelson, Karnes, Jason H, Satoh, Taijyu, Barndt, Robert J, Wu, Haodi, Parikh, Victoria N, Wang, Jianrong, Zhang, Yingze, McNamara, Dennis, Li, Gang, Speyer, Gil, Wang, Bing, Shiva, Sruti, Kaufman, Brett, Kim, Seungchan, Gomez, Delphine, Mari, Bernard, Cho, Michael H, Boueiz, Adel, Pauciulo, Michael W, Southgate, Laura, Trembath, Richard C, Sitbon, Olivier, Humbert, Marc, Graf, Stefan, Morrell, Nicholas W, Rhodes, Christopher J, Wilkins, Martin R, Nouraie, Mehdi, Nichols, William C, Desai, Ankit A, Bertero, Thomas, Chan, Stephen Y

“…Hypoxic reprogramming of vasculature relies on genetic, epigenetic, and metabolic circuitry, but the control points are unknown. In pulmonary arterial…”
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Pnck overexpression in HER-2 gene-amplified breast cancer causes Trastuzumab resistance through a paradoxical PTEN-mediated process by Deb, Tushar B., Zuo, Annie H., Barndt, Robert J., Sengupta, Surojeet, Jankovic, Radmila, Johnson, Michael D.

“…The gene for Pregnancy Up-regulated Non-ubiquitous Calmodulin Kinase (Pnck), a novel calmodulin kinase, is expressed in roughly one-third of human breast…”
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Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2 by Yeo, Yee Hui, Shiao, Frank, Liu, Li-Ching O, Huang, Nanxi, Lai, Ying-Jung J, Barndt, Robert J, Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D, Lin, Chen-Yong

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Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex by Deb, Tushar B, Zuo, Annie H, Wang, Youhong, Barndt, Robert J, Cheema, Amrita K, Sengupta, Surojeet, Coticchia, Christine M, Johnson, Michael D

“…We have recently described a novel role for pregnancy-upregulated non-ubiquitous calmodulin kinase (Pnck) in the induction of ligand-independent epidermal…”
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PTEN-mediated ERK1/2 inhibition and paradoxical cellular proliferation following Pnck overexpression by Deb, Tushar, Barndt, Robert, Zuo, Annie, Sengupta, Surojeet, Coticchia, Christine, Johnson, Michael

“…Pregnancy upregulated non-ubiquitous calmodulin kinase (Pnck), a novel calmodulin kinase, is significantly overexpressed in breast and renal cancers. We…”
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Functions of E2A-HEB Heterodimers in T-Cell Development Revealed by a Dominant Negative Mutation of HEB by Barndt, Robert J., Dai, Meifang, Zhuang, Yuan

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells by Kiyomiya, Ken-ichi, Lee, Ming-Shyue, Tseng, I-Chu, Zuo, Hong, Barndt, Robert J, Johnson, Michael D, Dickson, Robert B, Lin, Chen-Yong

“…Matriptase and its cognate inhibitor, hepatocyte growth factor activator inhibitor-1 (HAI-1), have been implicated in carcinoma onset and malignant…”
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The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence by Dorus, Steve, Gilbert, Sandra L., Forster, Michele L., Barndt, Robert J., Lahn, Bruce T.

“…Theories predict that the long-term survival of duplicated genes requires their functional diversification, which can be accomplished by either…”
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Common origins of MDA-MB-435 cells from various sources with those shown to have melonoma properties by Rae, James M., Ramus, Susan J., Waltham, Mark, Armes, Jane E., Campbell, Ian G., Clarke, Robert, Barndt, Robert J., Johnson, Michael D., Thompson, Erik W.

“…Recently, the tissue origin of MDA-MB-435 cell line has been the subject of considerable debate. In this study, we set out to determine whether MDA-MB-435-DTP…”
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Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties by Rae, James M, Ramus, Susan J, Waltham, Mark, Armes, Jane E, Campbell, Ian G, Clarke, Robert, Barndt, Robert J, Johnson, Michael D, Thompson, Erik W

“…Recently, the tissue origin of MDA-MB-435 cell line has been the subject of considerable debate. In this study, we set out to determine whether MDA-MB-435-DTP…”
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Functional Replacement of the Mouse E2A Gene with a Human HEB cDNA by Zhuang, Yuan, Barndt, Robert J., Pan, Lihua, Kelley, Robert, Dai, Meifang

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Fkbp12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506 by XUEHONG XU, BING SU, FLEISCHER, Sidney, WEINIAN SHOU, BARNDT, Robert J, HANYING CHEN, HONGBO XIN, GUIFAN YAN, LINYUAN CHEN, DONGSHENG CHENG, HEITMAN, Joseph, YUAN ZHUANG

“…FK506-binding proteins (FKBP) are immunophilins that interact with the immunosuppressive drugs FK506 and rapamycin. Several FKBP family members such as FKBP12,…”
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Abstract 162: Multiancestry GWAS And Functional Genomics Analysis Of HNF1A Locus To Define Novel Pathogenic Mechanism For Ischemic Stroke by Hiwase, Harsh, Yue, Yunshan, Hoffman, Eric K, Wu, Haodi, Barndt, Robert J, Chan, Stephen Y, Hyacinth, Hyacinth I., Sun, Wei

“…Abstract only Background: Ischemic stroke (IS) disproportionately affects populations of African descent due to genetic predispositions. A multiancestry…”
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Tu1591 - Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2 by Yeo, Yee Hui, Shiao, Frank, Liu, Li-Ching O., Huang, Nanxi, Lai, Ying-Jung J., Barndt, Robert J., Tseng, Chun-Che, Wang, Jehng-Kang, Jia, Bailing, Johnson, Michael D., Lin, Chen-Yong

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