Search Results - "Barnawi, Ibrahim"
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Design, structural inspection of new bis(1H-benzo[d]imidazol-2-yl)methanone complexes: Biomedical applications and theoretical implementations via DFT and docking approaches
Published in Inorganic chemistry communications (01-02-2023)“…[Display omitted] •Synthesis of new bis(1H-benzo[d]imidazol-2-yl) methanone complexes and their structural elucidation.•Geometry optimization for structural…”
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Brief in vitro IL-12 conditioning of CD8 + T Cells for anticancer adoptive T cell therapy
Published in Cancer Immunology, Immunotherapy (01-10-2021)“…Cancer immunotherapy represents a potential treatment approach through non-specific and specific enhancement of the immune responses. Adoptive cell therapy…”
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Synthesize, structural inspection, stoichiometry in solution and DFT calculation of some novel mixed ligand complexes: DNA binding, biomedical applications and molecular docking approach
Published in Journal of molecular liquids (01-04-2024)“…[Display omitted] •Synthesize of some novel mixed ligand complexes and their structural elucidation.•Geometry optimization for structural verification using…”
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Cytotoxicity, in silico predictions and molecular studies for androstane heterocycle compounds revealed potential antitumor agent against lung cancer cells
Published in Journal of biomolecular structure & dynamics (21-06-2022)“…The IL6/JAK2/STAT3 axis dysregulation and the related downstream pathways are a major contributor to the progression of non-small-cell lung carcinoma (NSCLC)…”
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Innovation, structural inspection for new mixed complexes: DNA binding, biomedical applications and molecular docking approaches
Published in Journal of Taibah University for Science (31-12-2024)“…2-Guanidinobenzimidazole (BIG) and Imidiazole (I) ligands were utilized to synthesize Cu(II), VO(II), Ag(I), and Pd(II) as mixed ligand complexes. All studied…”
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Immunomodulatory, apoptotic and anti-proliferative potentials of sildenafil in Ehrlich ascites carcinoma murine model: In vivo and in silico insights
Published in International immunopharmacology (01-06-2023)“…[Display omitted] •Sildenafil partially restored the proportions of splenic lymphocytes by promoting cytotoxic and helper T lymphocytes and lowering regulatory…”
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Nitric Oxide Synthase Potentiates the Resistance of Cancer Cell Lines to Anticancer Chemotherapeutics
Published in Anti-cancer agents in medicinal chemistry (01-01-2022)“…Despite the advancement in the fields of medical science and molecular biology, cancer is still the leading cause of death worldwide. Chemotherapy is a choice…”
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8
In Vitro Cytotoxic Evaluation and Apoptotic Effects of Datura innoxia Grown in Saudi Arabia and Phytochemical Analysis
Published in Applied sciences (01-03-2021)“…Datura innoxia is an important species of Solanaceae family with several purposes in folk medicine. This study intends to explore the cytotoxic effect of D…”
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Induction of apoptosis and cell cycle arrest by chloroform fraction of Juniperus phoenicea and chemical constituents analysis
Published in Open Chemistry (01-01-2021)“…Different phytochemicals from various plant species exhibit promising medicinal properties against cancer. is a plant species that has been found to present…”
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Design, preparation, physicochemical characterization, structural conformational, biological evaluation, and DNA interaction for some new benzimidazole complexes
Published in Applied organometallic chemistry (01-03-2024)“…New Cu (II), VO (II), Ag(I), and Pd (II)‐[BIP = 4,6‐dimethyl‐N‐(octahydro‐2H‐benzimidazol‐2‐ylidene)pyrimidin‐2‐amine] chelates have been synthesized by the…”
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11
Artemisia annua Extract Attenuate Doxorubicin-Induced Hepatic Injury via PI-3K/Akt/Nrf-2-Mediated Signaling Pathway in Rats
Published in International journal of molecular sciences (01-11-2023)“…Doxorubicin (DOX), which is used to treat cancer, has harmful effects that limit its therapeutic application. Finding preventative agents to thwart DOX-caused…”
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Design, synthesize, physicochemical characterization, nonlinear optical properties structural elucidation, biomedical studies, and DNA interaction of some new mixed ligand complexes incorporating 4,6‐dimethylpyrimidine derivative and imidazole ligand
Published in Applied organometallic chemistry (01-06-2024)“…This study was planned to prepare new mixed ligand chelates derived from N‐(4,6‐dimethylpyrimidin‐2‐yl)‐3a,4,5,6,7,7a‐hexahydro‐1H‐benzimidazol‐2‐amine (BIP),…”
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13
Microwave versus conventional synthesis, anticancer, DNA binding and docking studies of some 1,2,3-triazoles carrying benzothiazole
Published in Arabian journal of chemistry (01-03-2021)“…The present work describes the synthesis of new click products with a 2-mercapto-benzothiazole basic structure supporting the different functionalized side…”
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14
Fabrication, structural elucidation of some new metal chelates based on N-(1H-Benzoimidazol-2-yl)-guanidine ligand: DNA interaction, pharmaceutical studies and molecular docking approach
Published in Journal of molecular liquids (15-09-2023)“…[Display omitted] •Synthesis of new N-(1H-Benzoimidazol-2-yl)-guanidine complexes and their structural elucidation.•Geometry optimization for structural…”
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15
Fabrication, physicochemical characterization and theoretical studies of some new mixed ligands complexes based on N-(1H-benzimidazol-2-yl)-guanidine and 1, 10-phenanthroline: DNA interaction, biological applications and molecular docking approach
Published in Journal of molecular structure (15-08-2024)“…•Preparation of some new mixed ligand complexes and their structural inspection•Geometry optimization for structural verification using DFT calculation•DNA…”
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IArtemisia annua/I Extract Attenuate Doxorubicin-Induced Hepatic Injury via PI-3K/Akt/Nrf-2-Mediated Signaling Pathway in Rats
Published in International journal of molecular sciences (01-10-2023)“…Doxorubicin (DOX), which is used to treat cancer, has harmful effects that limit its therapeutic application. Finding preventative agents to thwart DOX-caused…”
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Anti-cancer activity, and molecular docking of novel hybrid heterocyclic steroids revealed promising anti-hepatocellular carcinoma agent: Implication of cyclin dependent kinase-2 pathway
Published in Steroids (01-05-2023)“…[Display omitted] •Synthesis of novel heterocyclic steroids has been done, and their cytotoxicity have been investigated in vitro.•Among the six new…”
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18
Evaluation of Dental Pulp Testing: Simple Literature Review
Published in Archives of pharmacy practice (01-07-2019)“…Background: As a dentist, a variety of tests available to help diagnose or monitor the treatment progress are important to understand in order to provide the…”
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