Search Results - "Barnard, Marinus"

β-Lactams against Tuberculosis — New Trick for an Old Dog? by Diacon, Andreas H, van der Merwe, Lize, Barnard, Marinus, von Groote-Bidlingmaier, Florian, Lange, Christoph, García-Basteiro, Alberto L, Sevene, Esperança, Ballell, Lluís, Barros-Aguirre, David

“…To the Editor: New treatments are needed to combat the worldwide increase in resistance to antituberculosis drugs. 1 The outlook for patients with tuberculosis…”
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Epidemic levels of drug resistant tuberculosis (MDR and XDR-TB) in a high HIV prevalence setting in Khayelitsha, South Africa by Cox, Helen S, McDermid, Cheryl, Azevedo, Virginia, Muller, Odelia, Coetzee, David, Simpson, John, Barnard, Marinus, Coetzee, Gerrit, van Cutsem, Gilles, Goemaere, Eric

“…Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such as South…”
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Using routinely collected laboratory data to identify high rifampicin-resistant tuberculosis burden communities in the Western Cape Province, South Africa: A retrospective spatiotemporal analysis by McIntosh, Avery I, Jenkins, Helen E, White, Laura F, Barnard, Marinus, Thomson, Dana R, Dolby, Tania, Simpson, John, Streicher, Elizabeth M, Kleinman, Mary B, Ragan, Elizabeth J, van Helden, Paul D, Murray, Megan B, Warren, Robin M, Jacobson, Karen R

“…South Africa has the highest tuberculosis incidence globally (781/100,000), with an estimated 4.3% of cases being rifampicin resistant (RR). Control and…”
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The diagnostic accuracy of the GenoType(®) MTBDRsl assay for the detection of resistance to second-line anti-tuberculosis drugs by Theron, Grant, Peter, Jonny, Richardson, Marty, Barnard, Marinus, Donegan, Sarah, Warren, Rob, Steingart, Karen R, Dheda, Keertan

“…Accurate and rapid tests for tuberculosis (TB) drug resistance are critical for improving patient care and decreasing the transmission of drug-resistant TB…”
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Rapid Molecular Screening for Multidrug-Resistant Tuberculosis in a High-Volume Public Health Laboratory in South Africa by Barnard, Marinus, Albert, Heidi, Coetzee, Gerrit, O'Brien, Richard, Bosman, Marlein E

“…The dual challenges to tuberculosis (TB) control of HIV infection and multidrug resistance are particularly pressing in South Africa. Conventional methods for…”
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Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory by Barnard, Marinus, Warren, Rob, Gey Van Pittius, Nico, van Helden, Paul, Bosman, Marlein, Streicher, Elizabeth, Coetzee, Gerrit, O'Brien, Richard

“…Conventional culture-based drug susceptibility testing (DST) for the second-line antituberculosis drugs is slow, leading to diagnostic delay with associated…”
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Implementation of GenoType MTBDRplus Reduces Time to Multidrug-Resistant Tuberculosis Therapy Initiation in South Africa by Jacobson, Karen R., Theron, Danie, Kendall, Emily A., Franke, Molly F., Barnard, Marinus, van Helden, Paul D., Victor, Tommie C., Streicher, Elizabeth M., Murray, Megan B., Warren, Robin M.

“…Background. Diagnosis of drug resistance and timely initiation of multidrug-resistant (MDR) tuberculosis therapy are essential to reduce transmission and…”
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Implications of Failure to Routinely Diagnose Resistance to Second-Line Drugs in Patients With Rifampicin-Resistant Tuberculosis on Xpert MTB/RIF: A Multisite Observational Study by Jacobson, Karen R., Barnard, Marinus, Kleinman, Mary B., Streicher, Elizabeth M., Ragan, Elizabeth J., White, Laura F., Shapira, Ofer, Dolby, Tania, Simpson, John, Scott, Lesley, Stevens, Wendy, van Helden, Paul D., Van Rie, Annelies, Warren, Robin M.

“…Background. Xpert MTB/RIF (Xpert) detects rifampicin-resistant tuberculosis (RR-tuberculosis), enabling physicians to rapidly initiate a World Health…”
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The use of digital PCR to improve the application of quantitative molecular diagnostic methods for tuberculosis by Devonshire, Alison S, O'Sullivan, Denise M, Honeyborne, Isobella, Jones, Gerwyn, Karczmarczyk, Maria, Pavšič, Jernej, Gutteridge, Alice, Milavec, Mojca, Mendoza, Pablo, Schimmel, Heinz, Van Heuverswyn, Fran, Gorton, Rebecca, Cirillo, Daniela Maria, Borroni, Emanuele, Harris, Kathryn, Barnard, Marinus, Heydenrych, Anthenette, Ndusilo, Norah, Wallis, Carole L, Pillay, Keshree, Barry, Thomas, Reddington, Kate, Richter, Elvira, Mozioğlu, Erkan, Akyürek, Sema, Yalçınkaya, Burhanettin, Akgoz, Muslum, Žel, Jana, Foy, Carole A, McHugh, Timothy D, Huggett, Jim F

“…Real-time PCR (qPCR) based methods, such as the Xpert MTB/RIF, are increasingly being used to diagnose tuberculosis (TB). While qualitative methods are…”
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Rapid sequencing of the Mycobacterium tuberculosis pncA gene for detection of pyrazinamide susceptibility by Streicher, Elizabeth M, Maharaj, Kashmeel, York, Talita, Van Heerden, Carel, Barnard, Marinus, Diacon, Andreas, Mendel, Carl M, Bosman, Marlein E, Hepple, Juli A, Pym, Alexander S, Warren, Robin M, van Helden, Paul D

“…We developed a pyrazinamidase gene DNA-sequencing method to rapidly identify pyrazinamide resistance-causing mutations in GenoLyse-treated, smear-positive…”
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GenoType MTBDR sl Line Probe Assay Shortens Time to Diagnosis of Extensively Drug-Resistant Tuberculosis in a High-Throughput Diagnostic Laboratory by Barnard, Marinus, Warren, Rob, Van Pittius, Nico Gey, van Helden, Paul, Bosman, Marlein, Streicher, Elizabeth, Coetzee, Gerrit, O’Brien, Richard

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GenoType MTBDRsI Line Probe Assay Shortens Time to Diagnosis of Extensively Drug-Resistant Tuberculosis in a High-Throughput Diagnostic Laboratory by BARNARD, Marinus, WARREN, Rob, VAN PITTIUS, Nico Gey, HELDEN, Paul Van, BOSMAN, Marlein, STREICHER, Elizabeth, COETZEE, Gerrit, O'BRIEN, Richard

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Epidemic Levels of Drug Resistant Tuberculosis by Cox, Helen S, McDermid, Cheryl, Azevedo, Virginia, Muller, Odelia, Coetzee, David, Simpson, John, Barnard, Marinus, Coetzee, Gerrit, van Cutsem, Gilles, Goemaere, Eric

“…Background Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such…”
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