Search Results - "Barnard, E A"

Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis by Nayeem, N, Green, T P, Martin, I L, Barnard, E A

“…In the transmitter-gated ion channel class of receptors, the members of which are all believed to be heterooligomers, the number and arrangement of the…”
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Functional characterization of the P2X4 receptor orthologues by Jones, C A, Chessell, I P, Simon, J, Barnard, E A, Miller, K J, Michel, A D, Humphrey, P P A

“…The aim of this study was to functionally characterize the recombinant mouse P2X4 receptor and to compare its pharmacological properties with those of the…”
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G protein-coupled receptors for ATP and other nucleotides: a new receptor family by Barnard, E A, Burnstock, G, Webb, T E

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Cloning and functional expression of a brain G-protein-coupled ATP receptor by Webb, Tania E., Simon, Joseph, Krishek, Belinda J., Bateson, Alan N., Smart, Trevor G., King, Brian F., Burnstock, Geoffrey, Barnard, Eric A.

“…A cDNA encoding a novel member of the G-protein-coupled receptor (GCR) superfamily, an ATP receptor, has been isolated from an embryonic chick whole brain cDNA…”
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The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase by Webb, Tania E., Feolde, Erick, Vigne, Paul, Neary, Joseph T., Runberg, Anna, Frelin, Christian, Barnard, Eric A.

“…1 BIO cells, a clonal line of rat brain capillary endothelial cells, exhibit a single P2 purinoceptor, activation of which leads to increases in free…”
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Localization of P2X purinoceptor transcripts in the rat nervous system by Kidd, E J, Grahames, C B, Simon, J, Michel, A D, Barnard, E A, Humphrey, P P

“…We used transcript-specific oligonucleotides to examine the localization in the rat nervous system of the corresponding mRNAs for the two P2X purinoceptor…”
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Activity of adenosine diphosphates and triphosphates on a P2YT‐type receptor in brain capillary endothelial cells by Simon, J, Vigne, P, Eklund, K M, Michel, A D, Carruthers, A M, Humphrey, P P A, Frelin, C, Barnard, E A

“…A P2Y (nucleotide) receptor activity in a clonal population (B10) of rat brain capillary endothelial cells is coupled to inhibition of adenylyl cyclase and has…”
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Phenotype Changes of the Vascular Smooth Muscle Cell Regulate P2 Receptor Expression as Measured by Quantitative RT-PCR by Erlinge, D., Hou, M., Webb, T.E., Barnard, E.A., Möller, S.

“…Studies using selective agonists have suggested that the contractile effect of extracellular nucleotides, such as ATP and UTP, in blood vessels is mediated…”
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Regional distribution of [35S]2'-deoxy 5'-O-(1-thio) ATP binding sites and the P2Y1 messenger RNA within the chick brain by WEBB, T. E, SIMON, J, BARNARD, E. A

“…The distribution of the P2Y1 receptor protein and transcript in the one-day-old chick brain were determined by quantitative in vitro ligand autoradiography and…”
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A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions by Sigel, E, Barnard, E A

“…A gamma-aminobutyrate/benzodiazepine receptor complex has been purified from bovine cerebral cortex by an improved procedure using a zwitterionic detergent. A…”
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International Union of Pharmacology. XIX. The IUPHAR receptor code: a proposal for an alphanumeric classification system by Humphrey, P P, Barnard, E A

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Sequence and functional expression of a single alpha subunit of an insect nicotinic acetylcholine receptor by Marshall, J., Buckingham, S. D., Shingai, R., Lunt, G. G., Goosey, M. W., Darlison, M. G., Sattelle, D. B., Barnard, E. A.

“…We report the isolation and sequence of a cDNA clone that encodes a locust (Schistocerca gregaria) nervous system nicotinic acetylcholine receptor (AChR)…”
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Inhibition by heterologously‐expressed P2Y2 nucleotide receptors of N‐type calcium currents in rat sympathetic neurones by Filippov, A K, Webb, T E, Barnard, E A, Brown, D A

“…The P2Y2 nucleotide receptor has previously been shown to stimulate phosphoinositide breakdown. We now show that, when P2Y2 receptors are heterologously…”
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G-Utrophin, the Autosomal Homologue of Dystrophin Dp116, is Expressed in Sensory Ganglia and Brain by Blake, D. J., Schofield, J. N., Zuellig, R. A., Górecki, D. C., Phelps, S. R., Barnard, E. A., Edwards, Y. H., Davies, K. E.

“…The utrophin gene is closely related to the dystrophin gene in both sequence and genomic structure. The Duchenne muscular dystrophy (DMD) locus encodes three…”
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Xenopus Oocytes express a unitary glutamate receptor endogenously by Soloviev, M.M., Barnard, E.A.

“…The results described here demonstrate that Xenopus oocytes endogenously express a unitary glutamate receptor subunit XenU1. The level of XenU1 mRNA expression…”
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α1B adrenergic receptors in gonadotrophin‐releasing hormone neurones: relation to Transport‐P by Al‐Damluji, S, Shen, W B, White, S, Barnard, E A

“…Peptidergic neurones accumulate amines via an unusual uptake process, designated Transport‐P. [3H]‐prazosin binds to α1 adrenoceptors on these cells and is…”
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Separate subunits for agonist and benzodiazepine binding in the gamma-aminobutyric acidA receptor oligomer by Casalotti, S O, Stephenson, F A, Barnard, E A

“…The gamma-aminobutyric acidA (GABAA) agonist muscimol can be photoactivated by 254 nm illumination to affinity label its binding site in the GABAA receptor. We…”
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Molecular biology of P2Y receptors expressed in the nervous system by Webb, T E, Barnard, E A

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Nucleotide receptors by North, R Alan, Barnard, Eric A

“…Adenosine 5′-triphosphate (ATP) and/or related nucleotides act at both ionotrophic (P2X) and metabotropic (P2Y) receptors. P2X receptors subunits (P2X 1—P2X 7)…”
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Stable Expression of Mammalian type A γ-Aminobutyric Acid Receptors in Mouse Cells: Demonstration of Functional Assembly of Benzodiazepine- Responsive Sites by Hadingham, Karen L., Harkness, Patricia C., McKernan, Ruth M., Quirk, Kathleen, Le Bourdelles, Beatrice, Horne, Anthony L., Kemp, John A., Barnard, Eric A., Ragan, C. Ian, Whiting, Paul J.

“…The differential sensitivity of type A γ-aminobutyric acid (GABAA) receptors to benzodiazepine ligands seen in the mammalian nervous system is thought to be…”
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