Search Results - "Barnard, C F"
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Ruthenium-Catalyzed Oxidative Heck Reactions
Published in Angewandte Chemie International Edition (04-01-2002)“…Aryl boronic acids can undergo a Heck‐type reaction catalyzed by RuII in the presence of CuII, which serves as a reoxidant in each cycle (see scheme, step 1)…”
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Biotransformation of the platinum drug JM216 following oral administration to cancer patients
Published in Cancer chemotherapy and pharmacology (1996)“…This study evaluates the metabolic profile of JM216 [bis(acetato)ammine-dichloro(cyclohexylamine) platinum(IV)], the first orally administrable platinum…”
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Interaction of a Nuclear Location Signal with Isolated Nuclear Envelopes and Identification of Signal-Binding Proteins by Photoaffinity Labeling
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1989)“…The nuclear envelope (NE) separates the two major compartments of eukaryotic cells, the nucleus and the cytoplasm. Recent studies suggest that the uptake of…”
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Bis(acetato)amminedichloro(cyclohexylamine)platinum(IV), an orally active anticancer drug
Published in Acta crystallographica. Section C, Crystal structure communications (15-05-1995)“…The structure of the anticancer drug bis(acetato)-amminedichloro(cyclohexylamine)platinum(IV), [PtCl2-(C2H3O2)2(C6H13N)(NH3)], is reported. The acetato groups…”
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Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its biotransformation products
Published in Anticancer research (01-07-1996)“…This study evaluates the metabolism of the oral platinum drug JM216 [bis(acetato) amminedichloro (cyclohexylamine)platinum (IV)] following oral administration…”
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Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin
Published in British journal of cancer (01-09-1994)“…Seventeen alkylamine ammine dicarboxylatodichloroplatinum(IV) complexes of general structure c,t,c-[PtCl2(OCOR1)2NH3(RNH2)], where R = aliphatic or alicyclic…”
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A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity
Published in Cancer research (Chicago, Ill.) (01-11-1994)“…As part of a drug discovery program to discover more effective platinum-based anticancer drugs, a series of platinum complexes of trans coordination geometry…”
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Synthesis and in Vitro and in Vivo Antitumor Activity of a Series of Trans Platinum Antitumor Complexes
Published in Journal of medicinal chemistry (01-08-1995)“…The synthesis of a series of platinum complexes of trans coordination geometry [centered around the general formula,…”
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DNA-binding properties of novel cis- and trans platinum-based anticancer agents in 2 human ovarian carcinoma cell lines
Published in International journal of cancer (15-09-1995)“…We have investigated the comparative initial DNA binding properties of 7 platinum-based anticancer drugs: 5 cis-oriented compounds, cisplatin, tetraplatin…”
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Oxidation States of Ruthenium and Osmium
Published in Platinum metals review (01-10-2004)“…Volume 5 in the book set "Comprehensive Coordination Chemistry Il" (CCCII) presents a survey of important developments in the chemistry of the transition…”
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Identification of Three Oligosaccharide Binding Sites in Ricin
Published in Biochemistry (Easton) (07-09-1999)“…The galactoside-binding sites of ricin B chain can be blocked by affinity-directed chemical modification using a reactive ligand derived from…”
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Novel trans platinum complexes: comparative in vitro and in vivo activity against platinum-sensitive and resistant murine tumours
Published in Anticancer research (01-01-1996)“…Two pairs of cis/trans platinum complexes, JM118 (cis-ammine(cyclohexylamine) dichloro platinum(II)) and its trans counterpart, JM334 and JM149…”
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Determination of metabolites of a novel platinum anticancer drug JM216 in human plasma ultrafiltrates
Published in Journal of pharmaceutical and biomedical analysis (01-11-1995)“…The present study describes the application of on-line liquid chromatography-electrospray ionisation in conjunction with a high resolution magnetic sector mass…”
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Oxidation States of Ruthenium and Osmium
Published in Platinum metals review (01-10-2004)Get full text
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Polymeric Platinum-Containing Anticancer Drugs
Published in Platinum metals review (01-07-2003)Get full text
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Applications of Coordination Complexes
Published in Platinum metals review (01-07-2004)Get full text
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Applications of Coordination Complexes
Published in Platinum metals review (01-07-2004)Get full text
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Baseline service level adjustment methodologies for energy efficiency projects on compressed air systems in the mining industry
Published in 2012 Proceedings of the 9th Industrial and Commercial Use of Energy Conference (01-08-2012)“…Compressed air systems used in the mining industry mainly supply compressed air to the underground operations of the mine. Underground pneumatic…”
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Contemporary Platinum Chemistry
Published in Platinum metals review (01-01-1998)Get full text
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