Search Results - "Barnard, C F"

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    Ruthenium-Catalyzed Oxidative Heck Reactions by Farrington, Edward J., Brown, John M., Barnard, C. F. J., Rowsell, E.

    Published in Angewandte Chemie International Edition (04-01-2002)
    “…Aryl boronic acids can undergo a Heck‐type reaction catalyzed by RuII in the presence of CuII, which serves as a reoxidant in each cycle (see scheme, step 1)…”
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    Journal Article
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    Biotransformation of the platinum drug JM216 following oral administration to cancer patients by RAYNAUD, F. I, MISTRY, P, DONAGHUE, A, POON, G. K, KELLAND, L. R, BARNARD, C. F. J, MURRER, B. A, HARRAP, K. R

    “…This study evaluates the metabolic profile of JM216 [bis(acetato)ammine-dichloro(cyclohexylamine) platinum(IV)], the first orally administrable platinum…”
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    Journal Article
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    Interaction of a Nuclear Location Signal with Isolated Nuclear Envelopes and Identification of Signal-Binding Proteins by Photoaffinity Labeling by Benditt, Joshua O., Meyer, Christa, Fasold, Hugo, Barnard, Faith C., Riedel, Norbert

    “…The nuclear envelope (NE) separates the two major compartments of eukaryotic cells, the nucleus and the cytoplasm. Recent studies suggest that the uptake of…”
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    Journal Article
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    Bis(acetato)amminedichloro(cyclohexylamine)platinum(IV), an orally active anticancer drug by Neidle, S, Snook, C F, Murrer, B A, Barnard, C F

    “…The structure of the anticancer drug bis(acetato)-amminedichloro(cyclohexylamine)platinum(IV), [PtCl2-(C2H3O2)2(C6H13N)(NH3)], is reported. The acetato groups…”
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    Journal Article
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    Metabolism, protein binding and in vivo activity of the oral platinum drug JM216 and its biotransformation products by Raynaud, F I, Boxall, F E, Goddard, P, Barnard, C F, Murrer, B A, Kelland, L R

    Published in Anticancer research (01-07-1996)
    “…This study evaluates the metabolism of the oral platinum drug JM216 [bis(acetato) amminedichloro (cyclohexylamine)platinum (IV)] following oral administration…”
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    Journal Article
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    Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin by ORR, R. M, O'NEILL, C. F, NICOLSON, M. C, BARNARD, C. F. J, MURRER, B. A, GIANDOMENICO, C. M, VOLLANO, J. F, HARRAP, K. R

    Published in British journal of cancer (01-09-1994)
    “…Seventeen alkylamine ammine dicarboxylatodichloroplatinum(IV) complexes of general structure c,t,c-[PtCl2(OCOR1)2NH3(RNH2)], where R = aliphatic or alicyclic…”
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    Journal Article
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    A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity by KELLAND, L. R, BARNARD, C. F. J, MELLISH, K. J, JONES, M, GODDARD, P. M, VALENTI, M, BRYANT, A, MURRER, B. A, HARRAP, K. R

    Published in Cancer research (Chicago, Ill.) (01-11-1994)
    “…As part of a drug discovery program to discover more effective platinum-based anticancer drugs, a series of platinum complexes of trans coordination geometry…”
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    Journal Article
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    DNA-binding properties of novel cis- and trans platinum-based anticancer agents in 2 human ovarian carcinoma cell lines by Mellish, K J, Barnard, C F, Murrer, B A, Kelland, L R

    Published in International journal of cancer (15-09-1995)
    “…We have investigated the comparative initial DNA binding properties of 7 platinum-based anticancer drugs: 5 cis-oriented compounds, cisplatin, tetraplatin…”
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    Journal Article
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    Oxidation States of Ruthenium and Osmium by Barnard, C. F. J., Bennett, S. C.

    Published in Platinum metals review (01-10-2004)
    “…Volume 5 in the book set "Comprehensive Coordination Chemistry Il" (CCCII) presents a survey of important developments in the chemistry of the transition…”
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    Journal Article
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    Identification of Three Oligosaccharide Binding Sites in Ricin by Steeves, Rita M, Denton, Mary E, Barnard, Faith C, Henry, Andrew, Lambert, John M

    Published in Biochemistry (Easton) (07-09-1999)
    “…The galactoside-binding sites of ricin B chain can be blocked by affinity-directed chemical modification using a reactive ligand derived from…”
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    Journal Article
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    Novel trans platinum complexes: comparative in vitro and in vivo activity against platinum-sensitive and resistant murine tumours by Goddard, P M, Orr, R M, Valenti, M R, Barnard, C F, Murrer, B A, Kelland, L R, Harrap, K R

    Published in Anticancer research (01-01-1996)
    “…Two pairs of cis/trans platinum complexes, JM118 (cis-ammine(cyclohexylamine) dichloro platinum(II)) and its trans counterpart, JM334 and JM149…”
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    Journal Article
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    Determination of metabolites of a novel platinum anticancer drug JM216 in human plasma ultrafiltrates by Poon, G.K., Mistry, P., Raynaud, F.I., Harrap, K.R., Murrer, B.A., Barnard, C.F.J.

    “…The present study describes the application of on-line liquid chromatography-electrospray ionisation in conjunction with a high resolution magnetic sector mass…”
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    Journal Article
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    Baseline service level adjustment methodologies for energy efficiency projects on compressed air systems in the mining industry by Barnard, F. C., Grobler, L. J.

    “…Compressed air systems used in the mining industry mainly supply compressed air to the underground operations of the mine. Underground pneumatic…”
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    Conference Proceeding
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