Search Results - "Barnado, April"
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Comparison of late-onset and non-late-onset systemic lupus erythematosus individuals in a real-world electronic health record cohort
Published in Lupus (01-04-2024)“…Objective: Late-onset systemic lupus erythematosus (LO-SLE) is defined as SLE diagnosed at age 50 years or later. Current studies on LO-SLE are small and have…”
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Rule-based and machine learning algorithms identify patients with systemic sclerosis accurately in the electronic health record
Published in Arthritis research & therapy (30-12-2019)“…Systemic sclerosis (SSc) is a rare disease with studies limited by small sample sizes. Electronic health records (EHRs) represent a powerful tool to study…”
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Phenome-wide association study identifies marked increased in burden of comorbidities in African Americans with systemic lupus erythematosus
Published in Arthritis research & therapy (10-04-2018)“…African Americans with systemic lupus erythematosus (SLE) have increased renal disease compared to Caucasians, but differences in other comorbidities have not…”
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Next-generation phenotyping: introducing phecodeX for enhanced discovery research in medical phenomics
Published in Bioinformatics (Oxford, England) (01-11-2023)“…Phecodes are widely used and easily adapted phenotypes based on International Classification of Diseases codes. The current version of phecodes (v1.2) was…”
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Contribution of viral infection to risk for cancer in systemic lupus erythematosus and multiple sclerosis
Published in PloS one (22-01-2021)“…Patients with autoimmune disorders (AD) have altered cancer risks compared to the general population. Systemic lupus erythematosus and multiple sclerosis lead…”
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Low prevalence of bone mineral density testing in patients with systemic lupus erythematosus and glucocorticoid exposure
Published in Lupus (01-03-2021)“…Summary Patients with systemic lupus erythematosus (SLE) have an increased risk of developing osteoporosis and fractures due to systemic inflammation and…”
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Identifying antinuclear antibody positive individuals at risk for developing systemic autoimmune disease: development and validation of a real-time risk model
Published in Frontiers in immunology (20-03-2024)“…Positive antinuclear antibodies (ANAs) cause diagnostic dilemmas for clinicians. Currently, no tools exist to help clinicians interpret the significance of a…”
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604 Identification of ACR guidelines for SLE pregnancy care in the electronic health record
Published in Lupus science & medicine (16-05-2024)“…IntroductionSLE is an autoimmune disease with an increased risk for poor outcomes in pregnancy. In 2020, ACR specified several recommendations to assist…”
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CD19 + CD21lo/neg cells are increased in systemic sclerosis-associated interstitial lung disease
Published in Clinical and experimental medicine (01-05-2022)“…Interstitial lung disease (ILD) represents a significant cause of morbidity and mortality in systemic sclerosis (SSc). The purpose of this study was to examine…”
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Natural language processing to identify lupus nephritis phenotype in electronic health records
Published in BMC medical informatics and decision making (03-03-2024)“…Systemic lupus erythematosus (SLE) is a rare autoimmune disorder characterized by an unpredictable course of flares and remission with diverse manifestations…”
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Systemic Lupus Erythematosus Delivery Outcomes Are Unchanged Across Three Decades
Published in ACR open rheumatology (01-08-2022)“…Objective Using a large, de‐identified electronic health record database with over 3.2 million patients, we aimed to identify trends of systemic lupus…”
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Human and Machine Intelligence Together Drive Drug Repurposing in Rare Diseases
Published in Frontiers in genetics (28-07-2021)“…Repurposing is an increasingly attractive method within the field of drug development for its efficiency at identifying new therapeutic opportunities among…”
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IgG4-Related Disease Presenting as Recurrent Mastoiditis With Central Nervous System Involvement
Published in JIM - high impact case reports (01-07-2014)“…We report a case of a 43-year-old female who presented with right ear fullness and otorrhea. She was initially diagnosed with mastoiditis that was not…”
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At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases
Published in Journal of leukocyte biology (01-02-2016)“…Clinical Review for Basic Researchers: NETs in autoimmune diseases, their potential as disease markers and therapeutic targets. Neutrophil extracellular traps…”
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Rates of Pneumocystis jirovecii pneumonia and prophylaxis prescribing patterns in a large electronic health record cohort of patients with systemic lupus erythematosus
Published in Seminars in arthritis and rheumatism (01-12-2022)“…Objective No guidelines exist for Pneumocystis jirovecii pneumonia (PJP) prophylaxis in patients with systemic lupus erythematosus (SLE). Limited data are…”
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Women with Rheumatoid Arthritis have similar rates of postpartum maternal outcomes compared to women without autoimmune disease
Published in Seminars in arthritis and rheumatism (01-04-2022)“…•To the best of our knowledge, our study is the only study that focuses on multiple maternal postpartum outcomes in women with RA.•To the best of our…”
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Phenotype Risk Score but Not Genetic Risk Score Aids in Identifying Individuals With Systemic Lupus Erythematosus in the Electronic Health Record
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-09-2023)“…Objective Systemic lupus erythematosus (SLE) poses diagnostic challenges. We undertook this study to evaluate the utility of a phenotype risk score (PheRS) and…”
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Developing electronic health record algorithms that accurately identify patients with juvenile idiopathic arthritis
Published in Seminars in arthritis and rheumatism (01-04-2023)“…•To the best of our knowledge, this is the first study to create an EHR-based JIA cohort using ICD codes, keywords, and exclusion criteria.•Three studied…”
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Developing Electronic Health Record Algorithms That Accurately Identify Patients With Systemic Lupus Erythematosus
Published in Arthritis care & research (2010) (01-05-2017)“…Objective To study systemic lupus erythematosus (SLE) in the electronic health record (EHR), we must accurately identify patients with SLE. Our objective was…”
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