Search Results - "Barnadas, Agust"

Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration by Tibau, Ariadna, Molto, Consolación, Ocana, Alberto, Templeton, Arnoud J, Del Carpio, Luis P, Del Paggio, Joseph C, Barnadas, Agustí, Booth, Christopher M, Amir, Eitan

“…It is uncertain whether drugs approved by the US Food and Drug Administration (FDA) have clinically meaningful benefit as determined by validated scales such…”
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Clinical benefit of breakthrough cancer drugs approved by the United States Food and Drug Administration by Molto, Consolacion, Hwang, Thomas J., Andres, Marta, Borrell, Maria, Gich Saladich, Ignasi J., Barnadas, Agust, Amir, Eitan, Kesselheim, Aaron S., Tibau Martorell, Ariadna

“…Abstract only 6513 Background: The Breakthrough Therapy program was established in July 2012 to expedite drug development and approval by the FDA. We compared…”
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Correlation between immune-related adverse events (irAEs) and efficacy in patients with solid tumors treated with immune-checkpoints inhibitors (ICIs) by Riudavets, Mariona, Barba, Andrés, Maroto, Pablo, SULLIVAN, IVANA GABRIELA, Anguera, Georgia, Páez, David, del Carpio, Luis, Callejo, Ana, Gonzalez Blanco, Cintia, Garcia Planellas, Esther, Castillo, Diego, Facundo, Carme, Genua, Idoia, Martin Lorente, Cristina, Virgili, Ana, Sebio, Ana, Gallego, Oscar, Lopez-Pousa, Antonio, Barnadas, Agust, Majem, Margarita

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Genetic variants in EGFR and its ligands to predict response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer by Sebio, Ana, Páez, David, Salazar, Juliana, Tobena, Maria, Martin-Richard, Marta, Barnadas, Agust, Baiget, Montserrat

“…Abstract only e14541 Background: Epidermal growth factor receptor (EGFR) activation via ligand binding results in signaling through several pathways that…”
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Risk of distant metastases in head and neck carcinoma patients and myeloperoxidase (MPO) expression by Lopez-Pousa, Antonio, Sumarroca, Anna, Quer, Miquel, Camacho, Mercedes, Garcia, Jacinto, Lopez, Montserrat, Duenas Cid, Nuria, Pavon, Miguel Angel, Farre, Nuria, Gallego Rubio, Oscar, Sullivan, Ivana GABRIELA, Barnadas, Agust, Leon, Xavier

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Prediction of lymph node involvement in breast cancer using RNA-sequencing and microRNA expression profile by Barnadas, Agust, Lopez-Vilaro, Laura, Arqueros, Cristina, Ramon y Cajal, Teresa, Murata, Eleonor Paola, Duch, Joan, Moral, Antonio, Mora, Josefina, Perez-Olabarria, Maitane, Vazquez, Tania, Garcia Valdecasas, Barbara, Lerma, Enrique, Escuin, Daniel

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MEK/ERK pathway characterization and its prognostic implication in gastric cancer (GC) by Martin-Richard, Marta, Tibau, Ariadna, Ferre, Malena, Castillo-Martin, Mireia, Colomer, Anna, Erill, Nadine, Sancho, Francesc, Gich, Ignasi, Barnadas, Agust

“…Abstract only e14552 Background: MEK/ERK pathway is considered one of the main controllers of cell proliferation and survival and its deregulation has been…”
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Expression of interleukin-1α (IL1-α) and risk of distant metastases (DM) in head and neck squamous cell carcinoma (HNSCC) by Lopez-Pousa, Antonio, Leon, Xavier, Camacho, Mercedes, Vila, Luis, SULLIVAN, IVANA GABRIELA, Lopez, Montserrat, Garcia, Jacinto, Anguera, Georgia, Arqueros, Cristina, Condori, Dhiossett, De Vega, Josep M., Farre, Nuria, Gallego Rubio, Oscar, Craven, Jordi, Quer, Miquel, Barnadas, Agust

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Testosterone levels as a prognostic factor for survival in patients with castrate-restistant prostate cancer (CRPC) by Gomez de Liaño, Alfonso, Maroto, José Pablo, Martin Lorente, Cristina, Cillan, Elena, Macias, Ismael, Stradella, Agostina, Sullivan, Ivana, Murata, Paola, Arqueros, Cristina, Anguera, Georgia, Condori, Dhiossett, Barnadas, Agust

“…Abstract only e15159 Background: To analyze the prognostic value for survival of the absolute levels of serum testosterone in patients under the definition of…”
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Effect of germline polymorphisms of DNA repair genes on chemotherapy outcome in advanced non-small cell lung cancer (NSCLC) patients by Sullivan, Ivana, Majem, Margarita, Páez, David, Pallares, Cinta, Paré, Laia, Del Rio, Elisabeth, Ramon Y Cajal, Teresa, Barnadas, Agust, Baiget, Montserrat

“…Abstract only e18057 Background: The identification of predictors of efficacy of chemotherapy in NSCLC could help in the selection of patients who are more…”
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Prognostic value of BRAF and KRAS mutations in colorectal cancer patients by Murata, Paola, Stradella, Agostina, Páez, David, Tobeña, Maria, Sebio, Ana, Paré, Laia, González, Alan, Espinosa, Iñigo, Targarona, Eduardo, Gich, Ignasi, Barnadas, Agust, Baiget, Montserrat, Martin-Richard, Marta

“…Abstract only e14104 Background: KRAS mutation has been established as a predictive marker of resistance to antiEGFR therapy in patients (pts) with colorectal…”
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Gene expression as a predictor of radiotherapy or chemoradiotherapy response in head and neck squamous cell carcinoma patients: A molecular approach by Lopez-Pousa, Antonio, Leon, Xavier, Quer, Miquel, Quintana, Ana, Vila, Luis, Camacho, Mercedes, Sullivan, Ivana, Gallego Rubio, Oscar, De Vega, Josep M., Farre, Nuria, Barnadas, Agust

“…Abstract only 5590 Background: There are not validated markers of radioresistance in patients with a head and neck squamous cell carcinoma (HNSCC). The…”
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Nabrax: Neoadjuvant therapy of breast cancer with weekly single-agent nab-paclitaxel—Final efficacy and biomarkers analysis of GEICAM 2011-02 trial by Martin, Miguel, Antolín, Silvia, Anton, Antonio, Plazaola, Arrate, García-Martínez, Elena, Seguí, Miguel Angel, Sanchez-Rovira, Pedro, Palacios, José, Calvo, Lourdes, Esteban, Carmen, Espinosa, Enrique, Guerrero, Angel, Batista, J. Norberto, Arance, Ana Maria, Barnadas, Agust, Carrasco, Eva Maria, Rodríguez-Martín, César, Caballero, Rosalia, Casas, Maribel, Chacon, Jose Ignacio

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Phase II study of oxaliplatin and sorafenib in advanced gastric cancer after failure of cisplatin-fluoropyrimidine-based (PF) treatment by Gallego, Rosa, Martin-Richard, Marta, Pericay, Carles, Garcia-Foncillas, Jesus, Queralt, Bernardo, Casado, Esther, Feliu, Jaime, Vega, Iranzazu, Juez, Ignacio, Visa, Laura, Saigí, Eugeni, Garcia-Albeniz, Xabier, Barnadas, Agust, Maurel, Joan

“…Abstract only 4079 Background: PF-based chemotherapy is the standard first line treatment in advanced GC. Although some drugs as taxanes or oxaliplatin (Ox)…”
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Efficacy and safety of weekly oral vinorelbine (NVBO) as single agent in first- or second-line metastatic breast cancer (MBC) by Morales, Serafin, Blancas, Isabel, Gonzalvez, Maria Luisa, Barnadas, Agust, Diaz, Nieves, Servitja, Sonia, del Barco, Sonia, Margeli, Mireia, Garcia Carbonero, Iciar, Alvarez, Ruth, Lopez de Ceballos, Maria Helena, Perez, Francisco Javier, Llombart Cussac, Antonio

“…Abstract only e11545 Background: NVBO has shown high activity and good safety profile when given as single agent chemotherapy (CT) for MBC. Oral CT…”
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Topoisomerase II alpha gene status, HER2, and microtubule-associated protein tau as predictors of pathologic complete response after neoadjuvant chemotherapy by Barnadas, Agust, Tibau Martorell, Ariadna, Lopez Vilaro, Laura, Escuin, Daniel, Alonso, M Carmen, Ojeda, Belen, Ramon y Cajal, Teresa, Fuentes, M Josefa, Perez Garcia, Jose Ignacio, Garcia Valdecasas, Barbara, Clotet, Montserrat, Torrubia, M Sofia, Gich, Ignasi, Lerma, Enrique

“…Abstract only 10555 Background: There is growing evidence that topoisomerase II-alpha (TOPOIIα) is a marker for anthracycline-, and microtubule-associated…”
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Feasibility of sentinel node biopsy in patients with locally advanced breast cancer after neoadjuvant therapy: A pilot study by Tibau Martorell, Ariadna, Duch, Joan, Quintana, Maria Jesus, Lopez Vilaro, Laura, Ojeda, Belen, Alonso, M Carmen, Ramon y Cajal, Teresa, Lerma, Enrique, Moral, Antonio, Capdevila, Enric, Pineda, Rosa, Sabate, Josep Maria, Estorch, Montserrat, Barnadas, Agust

“…Abstract only 1120 Background: Sentinel lymph node biopsy (SLNB) is a widely used staging method for patients with early breast cancer. Neoadjuvant Therapy…”
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Progressive increasing in the risk of second and subsequent malignant tumors in patients with a head and neck cancer: A validation study with SEER data by Leon, Xavier, Lopez-Pousa, Antonio, Villatoro, J Carlos, Quer, Miquel, Sullivan, Ivana, Murata, Paola, Stradella, Agostina, De Vega, Josep M., Farre, Nuria, Gallego Rubio, Oscar, Quintana, Maria Jesus, Barnadas, Agust, Alonso Martinez, Milagros

“…Abstract only 5595 Background: Patients with a head and neck squamous cell carcinoma (HNSCC) index tumor have a increased risk (2-4% per year) for appearance…”
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Randomized phase III study of adjuvant chemotherapy for node-positive early breast cancer (BC) patients (pts) comparing epirubicin plus cyclophosphamide followed by docetaxel (EC-T) versus epirubicin plus docetaxel followed by capecitabine (ET-X): Efficacy analysis of the GEICAM/2003-10 trial by Bermejo, Begoña, Ruiz, Amparo, Ruiz Borrego, Manuel, Ribelles, Nuria, Rodriguez-Lescure, Alvaro, Munoz-Mateu, Montserrat, Gonzalez, Sonia, Margeli, Mireia, Barnadas, Agust, Ramos Vazquez, Manuel, del Barco, Sonia, Calvo, Lourdes, Mendiola, Cesar, Crespo, Carmen, Rodriguez, Cesar Augusto, Martinez, Eduardo, Casas, Maria Isabel, Camara, M Carmen, Carrasco, Eva Maria, Martin, Miguel

“…Abstract only 1027 Background: X is an active drug in metastatic breast cancer. GEICAM/2003-10 is an adjuvant trial investigating the integration of…”
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Randomized phase III study of adjuvant chemotherapy for high-risk, node-negative breast cancer (BC) comparing FAC with FAC followed by weekly paclitaxel: First efficacy analysis of the GEICAM/2003-02 trial by Martin, Miguel, Lluch, Ana, Ruiz, Amparo, Ruiz Borrego, Manuel, Barnadas, Agust, Gonzalez, Sonia, Calvo, Lourdes, Margeli Vila, Mireia, Anton, Antonio, Rodriguez-Lescure, Alvaro, Seguí-Palmer, Miguel Angel, Munoz-Mateu, Montserrat, Dorca Ribugent, Joan, Lopez-Vega, Jose Manuel, Mendiola Fernandez, Cesar, Andres, Raquel, Plazaola, Arrate, Rodriguez, Cesar, Casas, Maria Isabel, Carrasco, Eva Maria

“…Abstract only 1001 Background: Adjuvant weekly paclitaxel (wP) sequential to anthracyclines improves the outcome of operable node-positive BC patients (pts)…”
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