Search Results - "Barman, Tarani Kanta"

Disease Tolerance during Viral-Bacterial Co-Infections by Barman, Tarani Kanta, Metzger, Dennis W

“…Disease tolerance has emerged as an alternative way, in addition to host resistance, to survive viral-bacterial co-infections. Disease tolerance plays an…”
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ADME, Pharmacokinetic Scaling, Pharmacodynamic and Prediction of Human Dose and Regimen of Novel Antiviral Drugs by Chaira, Tridib, Subramani, Chandru, Barman, Tarani Kanta

“…The search for new drugs is an extremely time-consuming and expensive endeavour. Much of that time and money go into generating predictive human…”
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Sequential targeting of interferon pathways for increased host resistance to bacterial superinfection during influenza by Barman, Tarani Kanta, Racine, Rachael, Bonin, Jesse L, Califano, Danielle, Salmon, Sharon L, Metzger, Dennis W

“…Bacterial co-infections represent a major clinical complication of influenza. Host-derived interferon (IFN) increases susceptibility to bacterial infections…”
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Azithromycin Exhibits Activity Against Pseudomonas aeruginosa in Chronic Rat Lung Infection Model by Kumar, Manoj, Rao, Madhvi, Mathur, Tarun, Barman, Tarani Kanta, Joshi, Vattan, Chaira, Tridib, Singhal, Smita, Pandya, Manisha, Al Khodor, Souhaila, Upadhyay, Dilip J, Masuda, Nobuhisa

“…forms biofilms in the lungs of chronically infected cystic fibrosis patients, which are tolerant to both the treatment of antibiotics and the host immune…”
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Cissampelos pareira Linn: Natural Source of Potent Antiviral Activity against All Four Dengue Virus Serotypes by Sood, Ruchi, Raut, Rajendra, Tyagi, Poornima, Pareek, Pawan Kumar, Barman, Tarani Kanta, Singhal, Smita, Shirumalla, Raj Kumar, Kanoje, Vijay, Subbarayan, Ramesh, Rajerethinam, Ravisankar, Sharma, Navin, Kanaujia, Anil, Shukla, Gyanesh, Gupta, Y K, Katiyar, Chandra K, Bhatnagar, Pradip K, Upadhyay, Dilip J, Swaminathan, Sathyamangalam, Khanna, Navin

“…Dengue, a mosquito-borne viral disease, poses a significant global public health risk. In tropical countries such as India where periodic dengue outbreaks can…”
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Lethal synergy between SARS-CoV-2 and Streptococcus pneumoniae in hACE2 mice and protective efficacy of vaccination by Barman, Tarani Kanta, Singh, Amit K, Bonin, Jesse L, Nafiz, Tanvir Noor, Salmon, Sharon L, Metzger, Dennis W

“…Secondary infections are frequent complications of viral respiratory infections, but the potential consequence of SARS-CoV-2 coinfection with common pulmonary…”
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Utilization of Bombyx mori larvae as a surrogate animal model for evaluation of the anti-infective potential of oxazolidinones by Barman, Tarani Kanta, Arora, Priya, Rao, Madhvi, Bhadauriya, Tripti, Upadhyay, Dilip J

“…Abstract Silkworm ( Bombyx mori ) larvae were investigated as an alternative animal model for the efficacy testing of novel oxazolidinones. The minimal lethal…”
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A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae by SAMUEL RAJ, V, TARANI KANTA BARMAN, SURASE, Yogesh B, VENKATARAMANAN, R, CHAKRABARTI, Anjan, DAS, Biswajit, BHATNAGAR, Pradip K, KALIA, Vandana, PURNAPATRE, Kedar, DUBE, Smita, RAMKUMAR, G, BHATEJA, Pragya, MATHUR, Tarun, CHAIRA, Tridib, UPADHYAY, Dilip J

“…We present here the novel ketolide RBx 14255, a semisynthetic macrolide derivative obtained by the derivatization of clarithromycin, for its in vitro and in…”
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Novel biaryl oxazolidinones: in vitro and in vivo activities with pharmacokinetics in an animal model by Barman, Tarani Kanta, Pandya, Manisha, Mathur, Tarun, Bhadauriya, Tripti, Rao, Madhvi, Khan, Seema, Singhal, Smita, Bhateja, Pragya, Sood, Ruchi, Malhotra, Sunita, Das, Biswajit, Paliwal, Jyoti, Bhatnagar, Pradip Kumar, Upadhyay, Dilip J

“…Abstract RBx 1000075 and RBx 1000276, the new investigational oxazolidinones, have an extended spectrum of in vitro activity against Gram-positive pathogens…”
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High content screening strategies for large-scale compound libraries with a focus on high-containment viruses by Subramani, Chandru, Sharma, Ghanshyam, Chaira, Tridib, Barman, Tarani Kanta

“…A majority of viral diseases do not have FDA-approved drugs. The recent outbreaks caused by SARS-CoV-2, monkeypox, and Sudan ebolavirus have exposed the…”
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Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies by Madan, Sumit, Nehate, Chetan, Barman, Tarani Kanta, Rathore, Anurag S., Koul, Veena

“…The study highlights the significance of co-application of bioactive components into liposomal gel formulations and their comparison to azithromycin for…”
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Efficacy of linezolid against Staphylococcus aureus in different rodent skin and soft tissue infections models by Rao, Madhvi, Barman, Tarani Kanta, Kumar, Manoj, Mathur, Tarun, Shukla, Gunjan, Bhati, Ashish, Kishore, Krishna, Chaira, Tridib, Pandya, Manisha, Upadhyay, Dilip J.

“…Linezolid is approved for complicated and uncomplicated skin and soft tissue infections. We have evaluated the efficacy of this drug in murine as well as in…”
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The PB1-F2 virulence protein regulates host ILC2 responses during influenza by Barman, Tarani Kanta, Califano, Danielle, Huber, Victor C., Metzger, Dennis W.

“…Abstract Influenza remains a major public health concern. The H1N1 PR8 and CA04 influenza viruses are both pandemic strains, yet they have distinct origins and…”
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Concomitant Delivery of Paclitaxel and NuBCP-9 peptide for synergistic enhancement of cancer therapy by Gupta, Dikshi, Kumar, Manoj, Tyagi, Priyanka, Kapoor, Sumeet, Tyagi, Amit, Barman, Tarani Kanta, Kharbanda, Surender, Kufe, Donald, Singh, Harpal

“…Paclitaxel (PTX) is a microtubule inhibitor administered as an albumin-bound nanoformulation for the treatment of breast cancer. However, the effectiveness of…”
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Viral PB1-F2 and host IFN-γ guide ILC2 and T cell activity during influenza virus infection by Barman, Tarani Kanta, Huber, Victor C, Bonin, Jesse L, Califano, Danielle, Salmon, Sharon L, McKenzie, Andrew N J, Metzger, Dennis W

“…Functional plasticity of innate lymphoid cells (ILCs) and T cells is regulated by host environmental cues, but the influence of pathogen-derived virulence…”
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In Vitro and In Vivo Activities of DS-2969b, a Novel GyrB Inhibitor, against Clostridium difficile by Mathur, Tarun, Barman, Tarani Kanta, Kumar, Manoj, Singh, Diksha, Kumar, Ram, Khera, Manoj Kumar, Yamada, Makiko, Inoue, Shin-Ichi, Upadhyay, Dilip Jatashankar, Masuda, Nobuhisa

“…DS-2969b is a novel GyrB inhibitor that is currently under clinical development for the treatment of infection (CDI). In this study, the and activities of…”
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Novel FtsZ inhibitor with potent activity against Staphylococcus aureus by Kumar, Manoj, Mathur, Tarun, Barman, Tarani Kanta, Chaira, Tridib, Kumar, Ram, Joshi, Vattan, Pandya, Manisha, Sharma, Lalima, Fujii, Kunihiko, Bandgar, Mahadev, Jadhav, Balasaheb, Bambal, Ramesh, Upadhyay, Dilip, Masuda, Nobuhisa, Verma, Ashwani Kumar, Bhatnagar, Pradip Kumar

“…Abstract Objectives FtsZ is an essential bacterial protein and an unexplored target for the development of antibacterial drugs. The development of a novel…”
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In Vitro and In Vivo Activities of DS-2969b, a Novel GyrB Inhibitor, and Its Water-Soluble Prodrug, DS11960558, against Methicillin-Resistant Staphylococcus aureus by Barman, Tarani Kanta, Kumar, Manoj, Mathur, Tarun, Namba, Eiko, Singh, Diksha, Chaira, Tridib, Kurosaka, Yuichi, Yamada, Makiko, Upadhyay, Dilip Jatashankar, Masuda, Nobuhisa

“…DS-2969b is a novel GyrB inhibitor under clinical development. In this study, the activity of DS-2969b and the activities of DS-2969b and its water-soluble…”
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DS86760016, a Leucyl-tRNA Synthetase Inhibitor with Activity against Pseudomonas aeruginosa by Kumar, Manoj, Rao, Madhvi, Purnapatre, Kedar P, Barman, Tarani Kanta, Joshi, Vattan, Kashyap, Amuliya, Chaira, Tridib, Bambal, Ramesh B, Pandya, Manisha, Khodor, Souhaila Al, Upadhyay, Dilip J, Masuda, Nobuhisa

“…DS86760016 is a new leucyl-tRNA-synthetase inhibitor at the preclinical development stage. DS86760016 showed potent activity against extended-spectrum…”
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Corrigendum to ‘Concomitant delivery of paclitaxel and NuBCP-9 peptide for synergistic enhancement of cancer therapy’ NANO 14 (2018) 1301-1313 by Gupta, Dikshi, Kumar, Manoj, Tyagi, Priyanka, Kapoor, Sumeet, Tyagi, Amit, Barman, Tarani Kanta, Kharbanda, Surender, Kufe, Donald, Singh, Harpal

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