Search Results - "Barmade, Mahesh A"
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1
Medicinal Chemistry Perspective of Fused Isoxazole Derivatives
Published in Current topics in medicinal chemistry (01-10-2016)“…Nitrogen containing heterocyclic rings with an oxygen atom is considered as one of the best combination in medicinal chemistry due to their diversified…”
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2
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer
Published in European journal of medicinal chemistry (13-11-2015)“…Breast cancer, an emerging disease among the women population, occurs due to overexpression of estrogens. The enzyme aromatase plays a key rate limiting role…”
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3
Unequivocal role of pyrazine ring in medicinally important compounds: a review
Published in Mini reviews in medicinal chemistry (01-10-2013)“…Pyrazine is one of the important class of heterocyclic compounds that can be obtained naturally or synthesized chemically. Pyrazine ring has got importance in…”
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4
Overview of the Development of DprE1 Inhibitors for Combating the Menace of Tuberculosis
Published in Journal of medicinal chemistry (11-10-2018)“…Decaprenylphosphoryl-β-d-ribose 2′-epimerase (DprE1), a vital enzyme for cell wall synthesis, plays a crucial role in the formation of lipoarabinomannan and…”
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5
Discovery of anti-malarial agents through application of in silico studies
Published in Combinatorial chemistry & high throughput screening (01-01-2015)“…Among the various parasitic diseases, malaria is the deadliest one. Due to the emergence of high drug resistance to the existing drug candidates there is a…”
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6
A comprehensive patents review on cannabinoid 1 receptor antagonists as antiobesity agents
Published in Expert opinion on therapeutic patents (03-10-2015)“…Obesity is a rapidly expanding worldwide health problem. Various targets are investigated presently for the treatment of obesity, but there remains an unmet…”
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7
Vicinal diaryl azole-based urea derivatives as potential cholesterol lowering agents acting through inhibition of SOAT enzymes
Published in European journal of medicinal chemistry (21-04-2017)“…A novel series of vicinal diaryl azole-urea derivatives were synthesized and evaluated for their potential to inhibit SOAT enzyme. Among the reported…”
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8
Synthesis and biological evaluation of 1-(5-(2-chloroquinolin-3-yl)-3-phenyl-1H-pyrazol-1-yl)ethanone derivatives as potential antimicrobial agents
Published in Journal of Saudi Chemical Society (01-11-2015)“…A novel series of 2-Chloroquinoline nucleus clubbed with the pyrazole ring has been synthesized and screened for antibacterial and antifungal activity. The…”
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9
Synthesis and biological evaluation of 1-(5-(2-chloroquinolin-3-yl)-3-phenyl-1hpyrazol-1-yl) ethanone derivatives as potential antimicrobial agents
Published in Journal of Saudi Chemical Society (2015)“…A novel series of 2-Chloroquinoline nucleus clubbed with the pyrazole ring has been synthesized and screened for antibacterial and antifungal activity. The…”
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