Search Results - "Barletta, Gabriel L"

Effect of Cyclodextrins Formulated in Liposomes and Gold and Selenium Nanoparticles on siRNA Stability in Cell Culture Medium by Castillo Cruz, Betzaida, Chinapen Barletta, Sandra, Ortiz Muñoz, Bryan G, Benitez-Reyes, Adriana S, Amalbert Perez, Omar A, Cardona Amador, Alexander C, Vivas-Mejia, Pablo E, Barletta, Gabriel L

“…Encapsulation of siRNA fragments inside liposome vesicles has emerged as an effective method for delivering siRNAs in vitro and in vivo. However, the…”
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A Fresh Look at the Potential of Cyclodextrins for Improving the Delivery of siRNA Encapsulated in Liposome Nanocarriers by Castillo Cruz, Betzaida, Flores Colón, Marienid, Rabelo Fernandez, Robert J, Vivas-Mejia, Pablo E, Barletta, Gabriel L

“…Liposomes are among the most effective vehicles to deliver siRNAs to cells, both in vitro and in vivo. However, despite numerous efforts to improve the…”
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Can an inactivating agent increase enzyme activity in organic solvent? Effects of 18-crown-6 on lipase activity, enantioselectivity, and conformation by Secundo, Francesco, Barletta, Gabriel L., Dumitriu, Emil, Carrea, Giacomo

“…Lipase from Burkholderia cepacia (lipase BC) and lipase B from Candida antarctica (CALB) show an increase of the transesterification activity in toluene (up to…”
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Effects of stabilizing additives on the activity of alpha-chymotrypsin in organic solvent by Secundo, Francesco, Barletta, Gabriel L., Parini, Gloria, Roda, Gabriella

“…[Display omitted] ► Transesterification activity in toluene of α-chymotrypsin lyophilized with additives. ► Extremolytes and methoxypoly(ethylene glycol) were…”
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Hydrogen/deuterium exchange study of subtilisin Carlsberg during prolonged exposure to organic solvents by Fasoli, Ezio, Ferrer, Amaris, Barletta, Gabriel L

“…It has been previously reported that prolonged exposure of an enzyme to organic solvents leads to substantial decrease of activity. This effect was found to be…”
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Kinetics of C(2α)-Proton Abstraction from 2-Benzylthiazolium Salts Leading to Enamines Relevant to Catalysis by Thiamin-Dependent Enzymes by Barletta, Gabriel L, Zou, Yu, Huskey, W. Phillip, Jordan, Frank

“…The kinetics of proton transfer from the C(2α) position of 2-(1-methoxybenzyl)thiazolium salts was studied for the p-H and p-N(CH3)3 + derivatives as models…”
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Biguanide-, imine-, and guanidine-based networks as catalysts for transesterification of vegetable oil by Bromberg, Lev, Fasoli, Ezio, Alvarez, Michael, Hatton, T. Alan, Barletta, Gabriel L.

“…Polycationic systems based on poly(hexamethylene biguanide) (PHMBG), branched polyethyleneimine (PEI) and poly(N-vinylguanidine) (PVG) have been evaluated as…”
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Effect of prolonged exposure to organic solvents on the active site environment of subtilisin Carlsberg by Bansal, Vibha, Delgado, Yamixa, Fasoli, Ezio, Ferrer, Amaris, Griebenow, Kai, Secundo, Francesco, Barletta, Gabriel L.

“…The potential of enzyme catalysis as a tool for organic synthesis is nowadays indisputable, as is the fact that organic solvents affect an enzyme's activity,…”
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The influence of the mode of enzyme preparation on enzymatic enantioselectivity in organic solvents and its temperature dependence by Noritomi, Hidetaka, Almarsson, Örn, Barletta, Gabriel L., Klibanov, Alexander M.

“…The enantioselectivities of subtilisin Carlsberg and Rhizomucor miehei lipase in organic solvents are found to strongly depend on the method by which the…”
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Activation of subtilisin Carlsberg in organic solvents by methyl-β-cyclodextrin: Lyoprotection versus substrate and product-complex effect by Fasoli, Ezio, Castillo, Betzaida, Santos, Angelica, Silva, Elsa, Ferrer, Amaris, Rosario, Eduardo, Griebenow, Kai, Secundo, Francesco, Barletta, Gabriel L.

“…Enzyme catalysis in organic solvents is a valuable tool for the synthesis of a number of important chiral compounds. However, their usually low activity in…”
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Reactions of Benzaldehyde with Thiazolium Salts in Me2SO: Evidence for Initial Formation of 2-(.alpha.-Hydroxybenzyl)thiazolium by Nucleophilic Addition, and for Dramatic Solvent Effects on Benzoin Formation by Chen, Yao-Tsung, Barletta, Gabriel L, Haghjoo, Khadijah, Cheng, Jung Tsang, Jordan, Frank

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Hydrogen/deuterium exchange study of subtilisin Carlsberg during prolonged exposure to organic solvents; Hydrogen/deuterium exchange study of subtilisin Carlsberg during prolonged exposure to organic solvents by Fasoli, Ezio, Ferrer, Amaris, Barletta, Gabriel L

“…It has been previously reported that prolonged exposure of an enzyme to organic solvents leads to substantial decrease of activity. This effect was found to be…”
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Delivery of Interference RNA Molecules to Ovarian Cancer Cells Using Gold‐Liposome Nanoparticle Conjugates by Quiñones‐Díaz, Blanca I., Grafals‐Ruiz, Nilmary, Barletta‐Bonanno, Gabriel L., Vivas‐Mejía, Pablo E.

“…RNA interference is a therapeutic modality in which RNA molecules, such as small interference RNAs (siRNAs) and microRNAs (miRNAs) (inhibitors and mimics), are…”
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Abstract 4409: Developing brain tumor-specific gold-liposomal nanocarriers for a noninvasive delivery of microRNA inhibitors by Grafals, Nilmary, Quiñoes-Diaz, Blanca I., Valle, Janixa Del, Barletta-Bonano, Gabriel L., Vivas-Mejía, Pablo E.

“…Abstract MicroRNAs are non-coding RNA molecules that regulate more than 60% of the protein coding genes and their dysregulation has proven to be involved in…”
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