Search Results - "Barker, Shannon D"

Targeting Adenovirus to the Serotype 3 Receptor Increases Gene Transfer Efficiency to Ovarian Cancer Cells by KANERVA, Anna, MIKHEEVA, Galina V, HEMMINKI, Akseli, CURIEL, David T, KRASNYKH, Victor, COOLIDGE, Candace J, LAM, John T, MAHASRESHTI, Parameshwar J, BARKER, Shannon D, STRAUGHN, Michael, BARNES, Mack N, ALVAREZ, Ronald D

“…Gene delivery efficiency in clinical cancer gene therapy trials with recombinant adenoviruses (Ads) based on serotype 5 (Ad5) has been limited partly because…”
Get full text

Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer by Ono, Hidetaka A, Davydova, Julia G, Adachi, Yasuo, Takayama, Koichi, Barker, Shannon D, Reynolds, Paul N, Krasnykh, Victor N, Kunisaki, Chikara, Shimada, Hiroshi, Curiel, David T, Yamamoto, Masato

“…Gastric cancer is the fourth most common malignancy worldwide. Adenoviral vectors (Ads) have been applied for gene therapy of various cancers because of their…”
Get full text

CD40 Is Expressed on Ovarian Cancer Cells and Can Be Utilized for Targeting Adenoviruses by HAKKARAINEN, Tanja, HEMMINKI, Akseli, PEREBOEV, Alexander V, BARKER, Shannon D, ASIEDU, Clement K, STRONG, Theresa V, KANERVA, Anna, WAHLFORS, Jarmo, CURIEL, David T

“…Purpose: CD40, a member of the tumor necrosis factor receptor superfamily, is widely expressed on various cell types in addition to hematopoietic cells. Recent…”
Get full text

The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy by Barker, Shannon D., Coolidge, Candace J., Kanerva, Anna, Hakkarainen, Tanja, Yamamoto, Masato, Liu, Bin, Rivera, Angel A., Bhoola, Snehal M., Barnes, Mack N., Alvarez, Ronald D., Curiel, David T., Hemminki, Akseli

“…Background Adenoviruses allow efficient transduction of dividing and non‐dividing cells and their safety for the treatment of cancer has been established in…”
Get full text

Strategies to Accomplish Targeted Expression of Transgenes in Ovarian Cancer for Molecular Therapeutic Applications by CASADO, Enrique, GOMEZ-NAVARRO, Jesus, GONZALEZ-BARON, Manuel, BARNES, Mack N, PUSTILNIK, Terri B, SIEGAL, Gene P, ALVAREZ, Ronald D, CURIEL, David T, YAMAMOTO, Masato, ADACHI, Yasuo, COOLIDGE, Candace J, ARAFAT, Waleed O, BARKER, Shannon D, WANG, Minghui H, MAHASRESHTI, Parameshwar J, HEMMINKI, Akseli

“…Purpose: The purpose of the study was to determine the capability of the midkine (MK) and cycooxygenase -2 (cox-2) gene promoter regions to function as…”
Get full text

Adenoviral gene therapy for cancer: from vectors to targeted and replication competent agents (review) by Bauerschmitz, Gerd J, Barker, Shannon D, Hemminki, Akseli

“…Gene therapy is an exciting novel approach for treating cancers resistant to currently available modalities. Treatment approaches are based on taking advantage…”
Get more information

Development of a Genomic DNA Reference Material Panel for Rett Syndrome ( MECP2 -Related Disorders) Genetic Testing by Kalman, Lisa V, Tarleton, Jack C, Percy, Alan K, Aradhya, Swaroop, Bale, Sherri, Barker, Shannon D, Bayrak-Toydemir, Pinar, Bridges, Christina, Buller-Burckle, Arlene M, Das, Soma, Iyer, Ramaswamy K, Vo, Timothy D, Zvereff, Val V, Toji, Lorraine H

“…Rett syndrome is a dominant X-linked disorder caused by point mutations (approximately 80%) or by deletions or insertions (approximately 15% to 18%) in the…”
Get full text

Development of Genomic Reference Materials for Cystic Fibrosis Genetic Testing by Pratt, Victoria M, Caggana, Michele, Bridges, Christina, Buller, Arlene M, DiAntonio, Lisa, Highsmith, W. Edward, Holtegaard, Leonard M, Muralidharan, Kasinathan, Rohlfs, Elizabeth M, Tarleton, Jack, Toji, Lorraine, Barker, Shannon D, Kalman, Lisa V

“…The number of different laboratories that perform genetic testing for cystic fibrosis is increasing. However, there are a limited number of quality control and…”
Get full text

Development and Characterization of Reference Materials for MTHFR , SERPINA1 , RET , BRCA1 , and BRCA2 Genetic Testing by Barker, Shannon D, Bale, Sherri, Booker, Jessica, Buller, Arlene, Das, Soma, Friedman, Kenneth, Godwin, Andrew K, Grody, Wayne W, Highsmith, Edward, Kant, Jeffery A, Lyon, Elaine, Mao, Rong, Monaghan, Kristin G, Payne, Deborah A, Pratt, Victoria M, Schrijver, Iris, Shrimpton, Antony E, Spector, Elaine, Telatar, Milhan, Toji, Lorraine, Weck, Karen, Zehnbauer, Barbara, Kalman, Lisa V

“…Well-characterized reference materials (RMs) are integral in maintaining clinical laboratory quality assurance for genetic testing. These RMs can be used for…”
Get full text

Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids by Lam, John T, Bauerschmitz, Gerd J, Kanerva, Anna, Barker, Shannon D, Straughn, J Michael, Wang, Minghui, Barnes, Mack N, Blackwell, Jerry L, Siegal, Gene P, Alvarez, Ronald D, Curiel, David T, Hemminki, Akseli

“…Replication competent viruses hold promise for treatment of advanced cancers resistant to available therapeutic modalities. Although preliminary clinical…”
Get full text