Search Results - "Barker, Peter E"

Towards Clinical Application of Methylated DNA Sequences as Cancer Biomarkers: A Joint NCI's EDRN and NIST Workshop on Standards, Methods, Assays, Reagents and Tools by Kagan, Jacob, Srivastava, Sudhir, Barker, Peter E, Belinsky, Steven A, Cairns, Paul

“…The workshop report, entitled Towards Clinical Application of Methylated DNA Sequences as Cancer Biomarkers: A Joint National Cancer Institute's Early…”
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Performance of mitochondrial DNA mutations detecting early stage cancer by Jakupciak, John P, Maragh, Samantha, Markowitz, Maura E, Greenberg, Alissa K, Hoque, Mohammad O, Maitra, Anirban, Barker, Peter E, Wagner, Paul D, Rom, William N, Srivastava, Sudhir, Sidransky, David, O'Connell, Catherine D

“…Mutations in the mitochondrial genome (mtgenome) have been associated with cancer and many other disorders. These mutations can be point mutations or…”
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Semiconductor nanocrystal probes for human metaphase chromosomes by Xiao, Yan, Barker, Peter E.

“…To improve signal stability and quantitation, an optically stable, novel class of fluorophore for hybridization analysis of human metaphase chromosomes is…”
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Quantum dots--a versatile tool in plant science? by Müller, Frank, Houben, Andreas, Barker, Peter E, Xiao, Yan, Käs, Josef A, Melzer, Michael

“…An optically stable, novel class of fluorophores (quantum dots) for in situ hybridisation analysis was tested to investigate their signal stability and…”
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Semiconductor nanocrystal conjugates, FISH and pH by Xiao, Yan, Telford, William G, Ball, J Christopher, Locascio, Laurie E, Barker, Peter E

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Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection by Xiao, Yan, Gao, Xiugong, Gannot, Gallya, Emmert‐Buck, Michael R, Srivastava, Sudhir, Wagner, Paul D., Amos, Michael D., Barker, Peter E.

“…In an effort to improve affinity biomarker validation in fixed patient tissue specimens, we have developed a novel quantum dot‐based bioimaging system that…”
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Cancer biomarker validation: standards and process: roles for the National Institute of Standards and Technology (NIST) by Barker, Peter E

“…Rigorous validation of biomarkers for early detection of cancer differs at the National Institute of Standards and Technology (NIST) from similar processes…”
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Inhibition of sulfur mustard-induced cytotoxicity and inflammation by the macrolide antibiotic roxithromycin in human respiratory epithelial cells by Gao, Xiugong, Ray, Radharaman, Xiao, Yan, Barker, Peter E, Ray, Prabhati

“…Sulfur mustard (SM) is a potent chemical vesicant warfare agent that remains a significant military and civilian threat. Inhalation of SM gas causes airway…”
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Mitochondrial DNA as a Cancer Biomarker by Jakupciak, John P, Wang, Wendy, Markowitz, Maura E, Ally, Delphine, Coble, Michael, Srivastava, Sudhir, Maitra, Anirban, Barker, Peter E, Sidransky, David, O'Connell, Catherine D

“…As part of a national effort to identify biomarkers for the early detection of cancer, we developed a rapid and high-throughput sequencing protocol for the…”
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Quantitative infrared spectroscopy of formalin-fixed, paraffin-embedded tissue specimens: paraffin wax removal with organic solvents by Meuse, Curtis W, Barker, Peter E

“…Formalin-fixed, paraffin-embedded tissue specimens form the basis for diagnostic histopathology. Although adequate for morphologic visualization, clinical…”
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Standards for Plasma and Serum Proteomics in Early Cancer Detection: A Needs Assessment Report from the National Institute of Standards and Technology-National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18-19, 2005 by Barker, Peter E, Wagner, Paul D, Stein, Stephen E, Bunk, David M, Srivastava, Sudhir, Omenn, Gilbert S

“…NIST and the National Cancer Institute cosponsored a workshop on August 18-19, 2005, to examine needs for reference materials for early cancer detection. This…”
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Validation of novel optical imaging technologies: the pathologists' view by Wells, Wendy A, Barker, Peter E, MacAulay, Calum, Novelli, Marco, Levenson, Richard M, Crawford, James M

“…Noninvasive optical imaging technology has the potential to improve the accuracy of disease detection and predict treatment response. Pathology provides the…”
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Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection by Barker, Peter E, Murthy, Mahadev

“…The anticipated biological and clinical utility of biomarkers has attracted significant interest recently. Aging and early cancer detection represent areas…”
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Preparation and Characterization of Candidate Reference Materials for Telomerase Assays by Jakupciak, John P, Barker, Peter E, Wang, Wendy, Srivastava, Sudhir, Atha, Donald H

“…Telomerase has been measured in body fluids of cancer patients, and clinical tests for telomerase may have utility as noninvasive, cost-effective methods for…”
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Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection by Barker, Peter E., Murthy, Mahadev

“…Peter E. Barker1 and Mahadev Murthy21Bioassay Methods Group, Biochemical Sciences Division, Bldg 227/B248, NIST, 100 Bureau Drive, Gaithersburg, Maryland…”
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Analytical Validation of Telomerase Activity for Cancer Early Detection: TRAP/PCR-CE and hTERT mRNA Quantification Assay for High-Throughput Screening of Tumor Cells by Jakupciak, John P, Wang, Wendy, Barker, Peter E, Srivastava, Sudhir, Atha, Donald H

“…Activation of telomerase plays a critical role in unlimited proliferation and immortalization of cells. Telomerase activity has been shown to correlate with…”
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Measurement reproducibility in the early stages of biomarker development by Liggett, Walter S, Barker, Peter E, Semmes, O John, Cazares, Lisa H

“…Biomarker discovery and development requires measurement reproducibility studies in addition to case-control studies. Parallel pursuit of reproducibility…”
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Inter-rater agreement on chromosome 5 breakage in FISH-based mutagen sensitivity assays (MSAs) by Barker, Peter E, Wang, Wendy, Wagner, Paul D, Pinsky, Paul

“…In chromosome breakage assays, validated, universal criteria for selection of cells and classification of chromosome aberrations may enhance their utility for…”
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Oxidative DNA damage biomarkers used in tissue engineered skin by Rodriguez, Henry, Jaruga, Pawel, Birincioğlu, Mustafa, Barker, Peter E, O'Connell, Catherine, Dizdaroğlu, Miral

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Standards requirements for systems biology approaches to health care: mitochondrial proteomics by Vásquez, Gregory B, Zullo, Steven J, Barker, Peter E

“…A review of the standards needs of the mitochondrial proteomics communities is presented based on the presentations and discussions at National Institute of…”
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