Search Results - "Barker, Jeffery L"

Self-Renewing and Differentiating Properties of Cortical Neural Stem Cells Are Selectively Regulated by Basic Fibroblast Growth Factor (FGF) Signaling via Specific FGF Receptors by Maric, Dragan, Fiorio Pla, Alessandra, Chang, Yoong Hee, Barker, Jeffery L

“…Developmental processes mediating the initiation of lineage commitment from self-renewing neural stem cells (NSCs) remain mostly unclear because of the…”
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Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis by Nielsen, Joseph A, Lau, Pierre, Maric, Dragan, Barker, Jeffery L, Hudson, Lynn D

“…Cortical development is a complex process that includes sequential generation of neuronal progenitors, which proliferate and migrate to form the stratified…”
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Canonical Transient Receptor Potential 1 Plays a Role in Basic Fibroblast Growth Factor (bFGF)/FGF Receptor-1-Induced Ca2+ Entry and Embryonic Rat Neural Stem Cell Proliferation by Pla, Alessandra Fiorio, Maric, Dragan, Brazer, So-Ching, Giacobini, Paolo, Liu, Xibao, Chang, Yoong Hee, Ambudkar, Indu S, Barker, Jeffery L

“…Basic fibroblast growth factor (bFGF) and its major receptor FGF receptor-1 (FGFR-1) play an important role in the development of the cortex. The mechanisms…”
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Prospective Cell Sorting of Embryonic Rat Neural Stem Cells and Neuronal and Glial Progenitors Reveals Selective Effects of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Self-Renewal and Differentiation by Maric, Dragan, Maric, Irina, Chang, Yoong Hee, Barker, Jeffery L

“…We directly isolated neural stem cells and lineage-restricted neuronal and glial progenitors from the embryonic rat telencephalon using a novel strategy of…”
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Identification of a Novel Oligodendrocyte Cell Adhesion Protein Using Gene Expression Profiling by Nielsen, Joseph A, Maric, Dragan, Lau, Pierre, Barker, Jeffery L, Hudson, Lynn D

“…Oligodendrocytes undergo extensive changes as they differentiate from progenitors into myelinating cells. To better understand the molecular mechanisms…”
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P11 (S100A10) as a potential biomarker of psychiatric patients at risk of suicide by Zhang, Lei, Su, Tung-Ping, Choi, Kwang, Maree, Webster, Li, Cheng-Ta, Chung, Ming-Yi, Chen, Ying-Sheue, Bai, Ya-Mei, Chou, Yuan-Hwa, Barker, Jeffery L, Barrett, James E, Li, Xiao Xia, Li, He, Benedek, David M, Ursano, Robert

“…Abstract Although suicide represents 1.8% of the global burden of disease, there are few objective assays for suicide risk. Being associated with depressive…”
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Development of an ischemic tolerance model in a PC12 cell line by Hillion, Joëlle A, Takahashi, Kenzo, Maric, Dragan, Ruetzler, Christl, Barker, Jeffery L, Hallenbeck, John M

“…Although ischemic tolerance has been described in a variety of primary cell culture systems, no similar in vitro models have been reported with any cell line…”
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Glutamate Acting at NMDA Receptors Stimulates Embryonic Cortical Neuronal Migration by Behar, Toby N, Scott, Catherine A, Greene, Carolyn L, Wen, Xiling, Smith, Susan V, Maric, Dragan, Liu, Qi-Ying, Colton, Carol A, Barker, Jeffery L

“…During cortical development, embryonic neurons migrate from germinal zones near the ventricle into the cortical plate, where they organize into layers…”
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Differential Response of Cortical Plate and Ventricular Zone Cells to GABA as a Migration Stimulus by Behar, Toby N, Schaffner, Anne E, Scott, Catherine A, O'Connell, Casey, Barker, Jeffery L

“…A microdissection technique was used to separate differentiated cortical plate (cp) cells from immature ventricular zone cells (vz) in the rat embryonic…”
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Activation of Phosphatidylinositol-3 Kinase (PI-3K) and Extracellular Regulated Kinases (Erk1/2) Is Involved in Muscarinic Receptor-Mediated DNA Synthesis in Neural Progenitor Cells by Li, Bing-Sheng, Ma, Wu, Zhang, Lei, Barker, Jeffery L, Stenger, David A, Pant, Harish C

“…Muscarinic acetylcholine receptor (mAChR), a member of the G-protein-coupled receptors (GPCRs) gene superfamily, has been shown to mediate the effects of…”
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Acetylcholine stimulates cortical precursor cell proliferation in vitro via muscarinic receptor activation and MAP kinase phosphorylation by Ma, Wu, Maric, Dragan, Li, Bing-sheng, Hu, Qian, Andreadis, Joanne D., Grant, Geraldine M., Liu, Qi-Ying, Shaffer, Kara M., Chang, Yoong H., Zhang, Lei, Pancrazio, Joseph J., Pant, Harish C., Stenger, David A., Barker, Jeffery L.

“…Increasing evidence has shown that some neurotransmitters act as growth‐regulatory signals during brain development. Here we report a role for the classical…”
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NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones by MacDermott, Amy B, Mayer, Mark L, Westbrook, Gary L, Smith, Stephen J, Barker, Jeffery L

“…Excitatory amino acids act via receptor subtypes in the mammalian central nervous system (CNS). The receptor selectively activated by N-methyl-D-aspartic acid…”
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Steroid Hormone Metabolites are Barbiturate-Like Modulators of the GABA Receptor by Majewska, Maria Dorota, Harrison, Neil L., Schwartz, Rochelle D., Barker, Jeffery L., Paul, Steven M.

“…Two metabolites of the steroid hormones progesterone and deoxycorticosterone, 3α-hydroxy-5α-dihydroprogesterone and 3α,5α-tetrahydrodeoxycorticosterone, are…”
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Functional Properties of Ryanodine Receptors in Hippocampal Neurons Change During Early Differentiation in Culture by Sukhareva, Manana, Smith, Susan V, Maric, Dragan, Barker, Jeffery L

“…Laboratory of Neurophysiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 Sukhareva,…”
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Astrocytes regulate developmental changes in the chloride ion gradient of embryonic rat ventral spinal cord neurons in culture by Li, Yong‐Xin, Schaffner, Anne E., Walton, Marc K., Barker, Jeffery L.

“…Embryonic rat ventral spinal cord neurons were dissociated at day 15 and grown on: (i) poly-D-lysine (PDL); (ii) a confluent monolayer of type I astrocytes; or…”
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Large-Scale Temporal Gene Expression Mapping of Central Nervous System Development by Wen, Xiling, Fuhrman, Stefanie, Michaels, George S., Carr, Daniel B., Smith, Susan, Barker, Jeffery L., Somogyi, Roland

“…We used reverse transcription--coupled PCR to produce a high-resolution temporal map of fluctuations in mRNA expression of 112 genes during rat central nervous…”
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Three-Dimensional Collagen Gel Networks for Neural Stem Cell-Based Neural Tissue Engineering by Ma, Wu, Chen, Silvia, Fitzgerald, Wendy, Maric, Dragan, Lin, Hsingch J., O'Shaughnessy, Thomas J., Kelly, Jeremy, Liu, Xiu-Huai, Barker, Jeffery L.

“…Stem and progenitor cells isolated from the embryonic rat cerebral cortex were immobilized by matrix entrapment in three‐dimensional (3D) Type I collagen gels,…”
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GABA Expression Dominates Neuronal Lineage Progression in the Embryonic Rat Neocortex and Facilitates Neurite Outgrowth via GABAA Autoreceptor/Cl{-} Channels by Maric, Dragan, Liu, Qi-Ying, Maric, Irina, Chaudry, Sabeen, Chang, Yoong-Hee, Smith, Susan V, Sieghart, Werner, Fritschy, Jean-Marc, Barker, Jeffery L

“…GABA emerges as a trophic signal during rat neocortical development in which it modulates proliferation of neuronal progenitors in the…”
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Levels of the potential biomarker p11 in peripheral blood cells distinguish patients with PTSD from those with other major psychiatric disorders by Su, Tung-Ping, Zhang, Lei, Chung, Ming-Yi, Chen, Ying-Sheue, Bi, Ya-Mei, Chou, Yuan-Hwa, Barker, Jeffery L, Barrett, James E, Maric, Dragan, Li, Xiao Xia, Li, He, Webster, Maree J, Benedek, David, Carlton, Janis R, Ursano, Robert

“…Abstract Posttraumatic stress disorder (PTSD) is a severely debilitating anxiety disorder. Over 80% of patients with PTSD also exhibit other psychiatric…”
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GABAB Receptors Mediate Motility Signals for Migrating Embryonic Cortical Cells by Behar, Toby N., Smith, Susan V., Kennedy, Robert T., Mckenzie, Jacinth M., Maric, Irina, Barker, Jeffery L.

“…During development, postmitotic neurons migrate from germinal regions into the cortical plate (cp), where lamination occurs. In rats, GABA is transiently…”
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