Search Results - "Barker, Jacqueline"

Advancing the preclinical study of comorbid neuroHIV and substance use disorders: Current perspectives and future directions by Namba, Mark D., Xie, Qiaowei, Barker, Jacqueline M.

“…•Human immunodeficiency virus (HIV) and substance use disorders (SUDs) are significant public health concerns worldwide.•Rates of drug use are…”
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Sex differences in incentive motivation and the relationship to the development and maintenance of alcohol use disorders by Barker, Jacqueline M., Taylor, Jane R.

“…Despite considerable evidence of higher rates of alcohol use disorders (AUDs) in men than in women, there is a dearth of research into the underlying causes of…”
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Arbitration of Approach-Avoidance Conflict by Ventral Hippocampus by Bryant, Kathleen G, Barker, Jacqueline M

“…When environmental cues or stimuli that represent both rewarding and aversive outcomes are presented, complex computations must be made in order to determine…”
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Habitual alcohol seeking: Modeling the transition from casual drinking to addiction by BARKER, Jacqueline M, TAYLOR, Jane R

“…The transition from goal-directed actions to habitual ethanol seeking models the development of addictive behavior that characterizes alcohol use disorders…”
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Sex Differences in Ethanol Reward Seeking Under Conflict in Mice by Xie, Qiaowei, Buck, Lauren A., Bryant, Kathleen G., Barker, Jacqueline M.

“…Background Alcohol use disorders are characterized by inflexible alcohol seeking that occurs despite adverse consequences. Males and females are differentially…”
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A history of low dose ethanol modulates ventral hippocampus activity during motivated behavior by Bryant, Kathleen G., Nothem, Mitch, Singh, Binay, Barker, Jacqueline M.

“…More than half of the 130 million people in the U.S. who consumed alcohol within the last month did so at a level that did not meet diagnostic criteria for an…”
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The Effect of Spared Nerve Injury on Ethanol Reward Seeking and Reinstatement by Nothem, Mitch A., Barker, Jacqueline M.

“…Alcohol use disorder (AUD) and chronic pain are complex and debilitating conditions that are difficult to treat, lead to enormous economic costs, and excessive…”
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Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking by Barker, Jacqueline M, Taylor, Jane R, De Vries, Taco J, Peters, Jamie

“…Abstract Many abused drugs lead to changes in endogenous brain-derived neurotrophic factor (BDNF) expression in neural circuits responsible for addictive…”
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Positive correlation between measures of habitual responding and motivated responding in mice by Bryant, Kathleen G., Barker, Jacqueline M.

“…Habit and motivation are thought to be separate processes, with motivated behavior often considered to be goal directed, whereas habits are defined by the…”
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Mice Exposed to Chronic low‐dose Ethanol Exhibit Reduced Sensitivity to Changes in Magnitude of Reward by Curran‐Alfaro, Christina M., Bryant, Kathleen G., Barker, Jacqueline M.

“…While approximately 2 billion individuals consume alcohol worldwide, the majority of these individuals to not exhibit drinking patterns consistent with alcohol…”
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Comorbid HIV infection and alcohol use disorders: Converging glutamatergic and dopaminergic mechanisms underlying neurocognitive dysfunction by Giacometti, Laura L., Barker, Jacqueline M.

“…•HIV and alcohol use disorder comorbidity increases risk for cognitive impairment.•Both HIV infection and chronic alcohol dysregulate common…”
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Astrocyte modulation of extinction impairments in ethanol-dependent female mice by Giacometti, Laura L., Chandran, Kelsey, Figueroa, Laura A., Barker, Jacqueline M.

“…Rates of alcohol use disorders are increasing in women, and there is growing evidence that both the cognitive and biological consequences of alcohol dependence…”
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Effects of ethanol on mechanical allodynia and dynamic weight bearing in male and female mice with spared nerve injury by Nothem, Mitchell A., Wickman, Jason R., Giacometti, Laura L., Barker, Jacqueline M.

“…Background Men and women with chronic pain report increased alcohol use and are more likely to be diagnosed with alcohol use disorder. The relationship between…”
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A Unifying Model of the Role of the Infralimbic Cortex in Extinction and Habits by Barker, Jacqueline M, Taylor, Jane R, Chandler, L. Judson

“…The infralimbic prefrontal cortex (IL) has been shown to be critical for the regulation of flexible behavior, but its precise function remains unclear. This…”
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Reinforcement History Dependent Effects of Low Dose Ethanol on Reward Motivation in Male and Female Mice by Bryant, Kathleen G, Singh, Binay, Barker, Jacqueline M

“…Alcohol use disorders (AUDs) are more prevalent in men than in women, though AUD diagnoses in women are growing rapidly, making an understanding of sex…”
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Regulation of Alcohol Extinction and Cue-Induced Reinstatement by Specific Projections among Medial Prefrontal Cortex, Nucleus Accumbens, and Basolateral Amygdala by Keistler, Colby R, Hammarlund, Emma, Barker, Jacqueline M, Bond, Colin W, DiLeone, Ralph J, Pittenger, Christopher, Taylor, Jane R

“…The ability to inhibit drinking is a significant challenge for recovering alcoholics, especially in the presence of alcohol-associated cues. Previous studies…”
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Infralimbic prefrontal cortex interacts with nucleus accumbens shell to unmask expression of outcome-selective Pavlovian-to-instrumental transfer by Keistler, Colby, Barker, Jacqueline M, Taylor, Jane R

“…Although several studies have examined the subcortical circuitry underlying Pavlovian-to-instrumental transfer (PIT), the role of medial prefrontal cortex in…”
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Brain region-dependent alterations in polysialic acid immunoreactivity across the estrous cycle in mice by Giacometti, Laura L., Huang, Fangyi, Hamilton, Brianna S., Barker, Jacqueline M.

“…N-glycosylation is a posttranslational modification that plays significant roles in regulating protein function. One form of N-glycosylation, polysialylation,…”
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Inactivation of Ventral Hippocampus Projections Promotes Sensitivity to Changes in Contingency by Barker, Jacqueline M, Bryant, Kathleen G, Chandler, L. Judson

“…The loss of behavioral flexibility is common across a number of neuropsychiatric illnesses. This may be in part due to the loss of the ability to detect or use…”
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Low prefrontal PSA-NCAM confers risk for alcoholism-related behavior by Barker, Jacqueline M, Torregrossa, Mary M, Taylor, Jane R

“…By examining natural behavioral variation of an outbred strain of mice on a Pavlovian-to-instrumental transfer task, the authors show that the level of…”
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