Search Results - "Barkaoui, Mohamed"
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1
Lung transplantation as a rescue option in childhood critical pulmonary Langerhans cell histiocytosis
Published in Pediatric pulmonology (01-01-2024)Get full text
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2
A circulating subset of BRAFV600E‐positive cells in infants with high‐risk Langerhans cell histiocytosis treated with BRAF inhibitors
Published in British journal of haematology (01-08-2021)“…Summary BRAF inhibitors are an effective treatment for BRAFV600E‐mutated, risk‐organ‐positive Langerhans cell histiocytosis (RO+ LCH). However, cell‐free…”
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3
Vemurafenib for Refractory Multisystem Langerhans Cell Histiocytosis in Children: An International Observational Study
Published in Journal of clinical oncology (01-11-2019)“…Off-label use of vemurafenib (VMF) to treat mutation-positive, refractory, childhood Langerhans cell histiocytosis (LCH) was evaluated. Fifty-four patients…”
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4
BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy
Published in Journal of clinical oncology (01-09-2016)“…Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes in children. The somatic…”
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5
Long‐term follow‐up of children with risk organ‐negative Langerhans cell histiocytosis after 2‐chlorodeoxyadenosine treatment
Published in British journal of haematology (01-12-2020)“…Summary The nucleoside analogue, 2‐chlorodeoxyadenosine (2CDA), was reported to be an active treatment for childhood Langerhans cell histiocytosis (LCH)…”
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6
Estimating the global prevalence of chronic obstructive pulmonary disease (COPD): a systematic review and meta-analysis
Published in BMC public health (25-01-2024)“…Chronic obstructive pulmonary disease (COPD) is a major public health problem. The present study aims to provide a global and regional estimate of the…”
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7
Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2 study
Published in Blood (17-09-2015)“…An international phase 2 study combining cladribine and cytarabine (Ara-C) was initiated for patients with refractory, risk-organ–positive Langerhans cell…”
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A circulating subset of BRAF V600E -positive cells in infants with high-risk Langerhans cell histiocytosis treated with BRAF inhibitors
Published in British journal of haematology (01-08-2021)“…BRAF inhibitors are an effective treatment for BRAF -mutated, risk-organ-positive Langerhans cell histiocytosis (RO LCH). However, cell-free BRAF DNA often…”
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9
Descriptive epidemiology of childhood Langerhans cell histiocytosis in France, 2000-2004
Published in Pediatric Blood & Cancer (01-07-2008)“…Introduction Childhood Langerhans cell histiocytosis (LCH) is a rare and poorly understood multisystemic disease. The French National Registry of Childhood…”
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10
Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads
Published in Blood (01-11-2024)“…Abstract Hematological involvement (HI) is one of the life-threatening risk organs (ROs) in Langerhans cell histiocytosis (LCH). Lahey criteria have defined HI…”
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11
Incidence and risk factors for clinical neurodegenerative Langerhans cell histiocytosis: a longitudinal cohort study
Published in British journal of haematology (01-11-2018)“…Neurodegenerative (ND) complications in Langerhans cell histiocytosis (LCH) are a late‐onset but dramatic sequelae for which incidence and risk factors are not…”
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12
Molecular and clinicopathologic characterization of pediatric histiocytoses
Published in American journal of hematology (01-07-2023)“…The spectrum of somatic mutations in pediatric histiocytoses and their clinical implications are not fully characterized, especially for non‐Langerhans cell…”
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13
Ethnobotanical survey on herbal remedies for the management of type 2 diabetes in the Casablanca-Settat region, Morocco
Published in BMC complementary and alternative medicine (15-04-2024)“…Morocco faces a substantial public health challenge due to diabetes mellitus, affecting 12.4% of adults in 2023. The Moroccan population makes extensive use of…”
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14
The use of plants in the traditional treatment of diabetes patients: survey in southern Morocco
Published in Notulae scientia biologicae (28-11-2022)“…This study was conducted in public healthcare establishments in Guelmim city in south of Morocco to report medicinal plants used in folk medicine to treat…”
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15
Circulating cell-free BRAF V600E as a biomarker in children with Langerhans cell histiocytosis
Published in British journal of haematology (01-08-2017)“…The BRAF mutation is reported in half of patients with Langerhans cell histiocytosis (LCH). This study investigated the detection of the BRAF allele in…”
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Circulating cell‐free BRAFV600E as a biomarker in children with Langerhans cell histiocytosis
Published in British journal of haematology (01-08-2017)“…Summary The BRAFV600E mutation is reported in half of patients with Langerhans cell histiocytosis (LCH). This study investigated the detection of the BRAFV600E…”
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17
Central Diabetes Insipidus as the Inaugural Manifestation of Langerhans Cell Histiocytosis: Natural History and Medical Evaluation of 26 Children and Adolescents
Published in The journal of clinical endocrinology and metabolism (01-09-2011)“…Context: Isolated central diabetes insipidus (CDI) can be the first manifestation of Langerhans cell histiocytosis (LCH), creating diagnostic dilemmas such as…”
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Efficacy of vinblastine in central nervous system Langerhans cell histiocytosis: a nationwide retrospective study
Published in Orphanet journal of rare diseases (12-12-2011)“…Vinblastine (VBL) is the standard treatment for systemic Langerhans cell histiocytosis (LCH), but little is known about its efficacy in central nervous system…”
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Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study
Published in Orphanet journal of rare diseases (09-09-2020)“…Abstract Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe…”
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20
Chest computed tomography findings for a cohort of children with pulmonary Langerhans cell histiocytosis
Published in Pediatric blood & cancer (01-10-2020)“…ABSTRACT Objective This study was undertaken to describe the spectrum of lung computed‐tomography (CT) findings in children with pulmonary Langerhans cell…”
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