Search Results - "Barish, Syndi"

Novel determinants of mammalian primary microRNA processing revealed by systematic evaluation of hairpin-containing transcripts and human genetic variation by Roden, Christine, Gaillard, Jonathan, Kanoria, Shaveta, Rennie, William, Barish, Syndi, Cheng, Jijun, Pan, Wen, Liu, Jun, Cotsapas, Chris, Ding, Ye, Lu, Jun

“…Mature microRNAs (miRNAs) are processed from hairpin-containing primary miRNAs (pri-miRNAs). However, rules that distinguish pri-miRNAs from other…”
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Evaluating optimal therapy robustness by virtual expansion of a sample population, with a case study in cancer immunotherapy by Barish, Syndi, Ochs, Michael F., Sontag, Eduardo D., Gevertz, Jana L.

“…Cancer is a highly heterogeneous disease, exhibiting spatial and temporal variations that pose challenges for designing robust therapies. Here, we propose the…”
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Molecular Genetics and Complex Inheritance of Congenital Heart Disease by Diab, Nicholas S, Barish, Syndi, Dong, Weilai, Zhao, Shujuan, Allington, Garrett, Yu, Xiaobing, Kahle, Kristopher T, Brueckner, Martina, Jin, Sheng Chih

“…Congenital heart disease (CHD) is the most common congenital malformation and the leading cause of mortality therein. Genetic etiologies contribute to an…”
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Abstract 4142546: Single-Nucleus RNA Sequencing Reveals Region-Specific Cell Composition and Transcriptional Variations in Cardiac Sarcoidosis by Neyazi, Meraj, Kim, Yuri, Brown, Kemar, Barish, Syndi, Gorham, Joshua, Layton, Olivia, Viveiros, Anissa, DeLaughter, Daniel, Beyer, Martin, Strohmenger, Viktoria, Reichart, Daniel, Bowles, Dawn, Glass, Carolyn, Oudit, Gavin, Seidman, Jonathan, Seidman, Christine

“…Abstract only Introduction: Sarcoidosis is a granulomatous disease of unknown cause that can affect any organ. Cardiac involvement, indicated by arrhythmias,…”
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The H2Bub1-deposition complex is required for human and mouse cardiogenesis by Barish, Syndi, Berg, Kathryn, Drozd, Jeffrey, Berglund-Brown, Isabella, Khizir, Labeeqa, Wasson, Lauren K, Seidman, Christine E, Seidman, Jonathan G, Chen, Sidi, Brueckner, Martina

“…De novo variants affecting monoubiquitylation of histone H2B (H2Bub1) are enriched in human congenital heart disease. H2Bub1 is required in stem cell…”
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Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility by Robson, Andrew, Makova, Svetlana Z., Barish, Syndi, Zaidi, Samir, Mehta, Sameet, Drozd, Jeffrey, Jin, Sheng Chih, Gelb, Bruce D., Seidman, Christine E., Chung, Wendy K., Lifton, Richard P., Khokha, Mustafa K., Brueckner, Martina

“…Genomic analyses of patients with congenital heart disease (CHD) have identified significant contribution frommutations affecting cilia genes and chromatin…”
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Tissue-Specific H2Bub1 Is Required for Cardiomyocyte Development by Barish, Syndi Marissa

“…Currently, the most common birth defect is congenital heart disease (CHD). Whole-exome sequencing of CHD patients identified variants affecting chromatin…”
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Characterization of 16 microsatellite markers for the Oreinotinus clade of Viburnum (Adoxaceae)1 by Barish, Syndi, Arakaki, Mónica, Edwards, Erika J., Donoghue, Michael J., Clement, Wendy L.

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Characterization of 16 Microsatellite Markers for the Oreinotinus Clade of Viburnum (Adoxaceae) by Barish, Syndi, Arakaki, Mónica, Edwards, Erika J, Donoghue, Michael J, Clement, Wendy L

“…Premise of the study: Microsatellite loci were isolated from four species of Viburnum (Adoxaceae) to study population structure and assess species boundaries…”
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