Search Results - "Barik, Subhasis"
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IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage
Published in The Journal of immunology (1950) (15-10-2017)“…Early thymic progenitors (ETPs) are endowed with diverse potencies and can give rise to myeloid and lymphoid lineage progenitors. How the thymic environment…”
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2
On the Role IL-4/IL-13 Heteroreceptor Plays in Regulation of Type 1 Diabetes
Published in The Journal of immunology (1950) (01-08-2017)“…Type 1 diabetes (T1D) manifests when the insulin-producing pancreatic β cells are destroyed as a consequence of an inflammatory process initiated by…”
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3
IL-4 and IL-13 Guide Early Thymic Progenitors To Mature toward Dendritic Cells
Published in The Journal of immunology (1950) (15-11-2018)“…Recently we reported that IL-4 and IL-13 signaling in murine early thymic progenitors (ETPs) expressing the heteroreceptor (HR) comprising IL-4 receptor α…”
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4
A proficient two stage model for identification of promising gene subset and accurate cancer classification
Published in International journal of information technology (Singapore. Online) (01-03-2023)“…Over the past few decades, there has been a massive growth in the volume of biological data. In such datasets, the influence of dimensionality bias or…”
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5
IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis
Published in The Journal of immunology (1950) (01-10-2017)“…IL-4 and IL-13 have been defined as anti-inflammatory cytokines that can counter myelin-reactive T cells and modulate experimental allergic encephalomyelitis…”
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6
Tumor-derived vascular pericytes anergize Th cells
Published in The Journal of immunology (1950) (15-07-2013)“…Immune evasion within the tumor microenvironment supports malignant growth and is also a major obstacle for successful immunotherapy. Multiple cellular…”
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7
Neem leaf glycoprotein prophylaxis transduces immune dependent stop signal for tumor angiogenic switch within tumor microenvironment
Published in PloS one (12-11-2014)“…We have reported that prophylactic as well as therapeutic administration of neem leaf glycoprotein (NLGP) induces significant restriction of solid tumor growth…”
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8
In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity
Published in Frontiers in cell and developmental biology (13-05-2022)“…Early T precursor acute lymphoblastic leukemia (ETP-ALL) exhibits poor clinical outcomes and high relapse rates following conventional chemotherapeutic…”
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Familiarity Breeds Strategy: In Silico Untangling of the Molecular Complexity on Course of Autoimmune Liver Disease-to-Hepatocellular Carcinoma Transition Predicts Novel Transcriptional Signatures
Published in Cells (Basel, Switzerland) (29-07-2021)“…Autoimmune liver diseases (AILD) often lead to transformation of the liver tissues into hepatocellular carcinoma (HCC). Considering the drawbacks of surgical…”
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10
Neem leaf glycoprotein prevents post-surgical sarcoma recurrence in Swiss mice by differentially regulating cytotoxic T and myeloid-derived suppressor cells
Published in PloS one (17-04-2017)“…Post-surgical tumor recurrence is a common problem in cancer treatment. In the present study, the role of neem leaf glycoprotein (NLGP), a novel…”
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11
Neem leaf glycoprotein activates CD8(+) T cells to promote therapeutic anti-tumor immunity inhibiting the growth of mouse sarcoma
Published in PloS one (2013)“…In spite of sufficient data on Neem Leaf Glycoprotein (NLGP) as a prophylactic vaccine, little knowledge currently exists to support the use of NLGP as a…”
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12
Normalization of tumor microenvironment by neem leaf glycoprotein potentiates effector T cell functions and therapeutically intervenes in the growth of mouse sarcoma
Published in PloS one (13-06-2013)“…We have observed restriction of the murine sarcoma growth by therapeutic intervention of neem leaf glycoprotein (NLGP). In order to evaluate the mechanism of…”
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13
Novel role of Wag31 in protection of mycobacteria under oxidative stress
Published in Molecular microbiology (01-07-2009)“…Wag31 of Mycobacterium tuberculosis belongs to the DivIVA family of proteins known to regulate cell morphology in Gram-positive bacteria. Here we demonstrate…”
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14
The HBV web: An insight into molecular interactomes between the hepatitis B virus and its host en route to hepatocellular carcinoma
Published in Journal of medical virology (01-01-2023)“…Hepatitis B virus (HBV) is a major aetiology associated with the development and progression of hepatocellular carcinoma (HCC), the most common primary liver…”
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15
Antimicrobial Activity of Trigonelline Hydrochloride Against Pseudomonas aeruginosa and Its Quorum-Sensing Regulated Molecular Mechanisms on Biofilm Formation and Virulence
Published in ACS infectious diseases (09-02-2024)“…Pseudomonas aeruginosa, a vivid biofilm-producing bacterium, is considered a dreadful opportunistic pathogen, and thus, management of biofilm-associated…”
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16
RseA, the SigE specific anti‐sigma factor of Mycobacterium tuberculosis, is inactivated by phosphorylation‐dependent ClpC1P2 proteolysis
Published in Molecular microbiology (01-02-2010)“…Summary Central to the response of Mycobacterium tuberculosis to environmental stress is the regulation of genes under the control of alternative sigma…”
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17
Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani
Published in European journal of medicinal chemistry (05-04-2024)“…Visceral leishmaniasis is a potentially fatal disease caused by infection by the intracellular protist pathogens Leishmania donovani or Leishmania infantum…”
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18
IL-4 and IL-13 guide early thymic progenitors to mature towards dendritic cells
Published in The Journal of immunology (1950) (05-10-2018)“…Recently we reported that IL-4 and IL-13 signaling in murine early thymic progenitors (ETPs) expressing the heteroreceptor (HR) comprising IL-4 receptor alpha…”
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Journal Article -
19
Type II Cytokines Fine-Tune Thymic T Cell Selection to Offset Murine Central Nervous System Autoimmunity
Published in The Journal of immunology (1950) (15-10-2020)“…Early thymic progenitors (ETPs) are bone marrow-derived hematopoietic stem cells that remain multipotent and give rise to a variety of lineage-specific cells…”
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20
Type II Cytokines Guide Early Thymic Progenitor Lineage Choice and Influence Negative Selection of Myelin-Reactive T cells
Published in The Journal of immunology (1950) (01-05-2018)“…Abstract IL-4 and IL-13 are considered anti-inflammatory cytokines and have been effective in sustaining peripheral T cell tolerance and modulation of…”
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