Search Results - "Barenholz, Y"

Immune Changes Induced by Orthodontic Forces: A Critical Review by Chaushu, S., Klein, Y., Mandelboim, O., Barenholz, Y., Fleissig, O.

“…Orthodontic tooth movement (OTM) is generated by a mechanical force that induces an aseptic inflammatory response in the periodontal tissues and a subsequent…”
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Using solution X-ray scattering to determine the high-resolution structure and morphology of PEGylated liposomal doxorubicin nanodrugs by Schilt, Y., Berman, T., Wei, X., Barenholz, Y., Raviv, U.

“…Among nanodrugs, PEGylated nanoliposomes loaded with an active agent are of major importance. In this paper we studied the structures and morphology of…”
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Cholesterol and other membrane active sterols: from membrane evolution to “rafts” by Barenholz, Y.

“…The appearance of “membrane-active sterols” in biological membranes of eukaryocytes is one of the major steps in membrane evolution. This is exemplified best…”
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Analysis of cellular water content in T cells reveals a switch from slow metabolic water gain to rapid water influx prior to cell division by Saragovi, A., Zilberman, T., Yasur, G., Turjeman, K., Abramovich, I., Kuchersky, M., Gottlieb, E., Barenholz, Y., Berger, M.

“…Cell growth is driven by the acquisition and synthesis of both dry biomass and water mass. In this study, we examine the increase of water mass in T cell…”
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Polymers for DNA delivery by Eliyahu, H, Barenholz, Y, Domb, A J

“…Nucleic acid delivery has many applications in basic science, biotechnology, agriculture, and medicine. One of the main applications is DNA or RNA delivery for…”
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A liposomal steroid nano-drug for treating systemic lupus erythematosus by Moallem, E, Koren, E, Ulmansky, R, Pizov, G, Barlev, M, Barenholz, Y, Naparstek, Y

“…Background Glucocorticoids have been known for years to be the most effective therapy in systemic lupus erythematosus. Their use, however, is limited by the…”
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Lipoplex-induced hemagglutination: potential involvement in intravenous gene delivery by ELIYAHU, H, SERVEL, N, DOMB, A. J, BARENHOLZ, Y

“…We report a study aiming to characterize the interaction of blood and blood components with lipoplexes under conditions relevant to in vivo intravenous…”
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Improved efficacy and reduced osteoporosis following methylprednisolone – Nano liposomes treatment in mdx mice by Yanay, N, Turgeman, K, Elbaz, M, Issa, B, Rabie, M, Barenholz, Y, Nevo, Y

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Liposomes as potential biolubricant additives for wear reduction in human synovial joints by Verberne, G., Schroeder, A., Halperin, G., Barenholz, Y., Etsion, I.

“…Wear processes occurring in synovial joints, mainly known as osteoarthritis (OA), affect many people worldwide. One of the symptoms of OA is wear of articular…”
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Adjuvant liposomal clodronate reduces periablational inflammatory cell recruitment and “off-target” stimulation of distant tumor growth after hepatic radiofrequency ablation (RFA) by Kumar, G, Goldberg, S, Wang, Y, Koren, E, Gourevich, L, Barenholz, Y, Ahmed, M

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Characterization and in vivo performance of dextran–spermine polyplexes and DOTAP/cholesterol lipoplexes administered locally and systemically by Eliyahu, H, Joseph, A, Schillemans, J.P, Azzam, T, Domb, A.J, Barenholz, Y

“…Abstract In this study, we compared two systems which can be applied for transfection in vitro and in vivo: polyplexes based on the polymer dextran–spermine…”
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Novel dextran-spermine conjugates as transfecting agents: comparing water-soluble and micellar polymers by ELIYAHU, H, MAKOVITZKI, A, AZZAM, T, ZLOTKIN, A, JOSEPH, A, GAZIT, D, BARENHOLZ, Y, DOMB, A. J

“…Recently, a novel cationic polymer, dextran-spermine (D-SPM) was developed for gene delivery. An efficient transfection was obtained using this polycation for…”
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Safety and efficacy of MM-II, an intra-articular injection of liposomes, in moderate knee osteoarthritis. Prospective randomized double-blinded study by Kandel, L, Dolev, Y, Rivkind, G, Liebergall, M, Mattan, Y, Barenholz, Y, Shimonov, R, Chevalier, X

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Nomenclature for synthetic gene delivery systems by Felgner, P L, Barenholz, Y, Behr, J P, Cheng, S H, Cullis, P, Huang, L, Jessee, J A, Seymour, L, Szoka, F, Thierry, A R, Wagner, E, Wu, G

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ROLE OF COMPLEMENT ACTIVATION IN HYPERSENSITIVITY REACTIONS TO DOXIL AND HYNIC PEG LIPOSOMES: EXPERIMENTAL AND CLINICAL STUDIES by Szebeni, J., Baranyi, L., Savay, S., Milosevits, J., Bunger, R., Laverman, P., Metselaar, J. M., Storm, G., Chanan-Khan, A., Liebes, L., Muggia, F. M., Cohen, R., Barenholz, Y., Alving, C. R.

“…ABSTRACT Pegylated liposomal doxorubicin (Doxil) and 99mTc-HYNIC PEG liposomes (HPL) were reported earlier to cause hypersensitivity reactions (HSRs) in a…”
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DRV liposomal bupivacaine: Preparation, characterization, and in Vivo evaluation in mice by GRANT, Gilbert J, BARENHOLZ, Yechezkel, PISKOUN, Boris, BANSINATH, Mylarrao, TURNDORF, Herman, BOLOTIN, Elijah M

“…To evaluate the dehydration-rehydration technique to prepare a formulation of liposomal bupivacaine, and to assess its analgesic efficacy. Bupivacaine…”
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Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery by Lasic, D.D., Čeh, B., Stuart, M.C.A., Guo, L., Frederik, P.M., Barenholz, Y.

“…Phase transitions in closed vesicles, i.e., microenvironments defined by the size of the vesicle, its contents, and permeability of its membrane are becoming…”
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Gelation of liposome interior A novel method for drug encapsulation by Lasic, D.D., Frederik, P.M., Stuart, M.C.A., Barenholz, Y., McIntosh, T.J.

“…Liposomes can be loaded with weak acids and bases, which exist in solutions in equilibrium with membrane permeable uncharged form, using various gradients…”
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Liposomology by Barenholz, Yechezkel

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Optimization and upscaling of doxorubicin-containing liposomes for clinical use by Amselem, S, Gabizon, A, Barenholz, Y

“…This work describes the optimization of a doxorubicin (DXR)-containing liposome formulation and its upscaling for human therapy. Multilamellar vesicles (MLV)…”
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