Search Results - "Bardwell, J."

DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment by Zhang, Teng, Oatley, Jon, Bardwell, Vivian J, Zarkower, David

“…Male mammals produce sperm for most of postnatal life and therefore require a robust germ line stem cell system, with precise balance between self-renewal and…”
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Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis by Agrimson, Kellie S, Minkina, Anna, Sadowski, Danielle, Wheeler, Andrew, Murphy, Mark W, Gearhart, Micah D, Bardwell, Vivian J, Zarkower, David

“…The mammalian nuclear hormone receptors LRH1 (NR5A2) and SF1 (NR5A1) are close paralogs that can bind the same DNA motif and play crucial roles in gonadal…”
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DMRT1 Protects Male Gonadal Cells from Retinoid-Dependent Sexual Transdifferentiation by Minkina, Anna, Matson, Clinton K., Lindeman, Robin E., Ghyselinck, Norbert B., Bardwell, Vivian J., Zarkower, David

“…Mammalian sex determination initiates in the fetal gonad with specification of bipotential precursor cells into male Sertoli cells or female granulosa cells…”
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EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis by Béguelin, Wendy, Teater, Matt, Gearhart, Micah D., Calvo Fernández, María Teresa, Goldstein, Rebecca L., Cárdenas, Mariano G., Hatzi, Katerina, Rosen, Monica, Shen, Hao, Corcoran, Connie M., Hamline, Michelle Y., Gascoyne, Randy D., Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Shaknovich, Rita, Elemento, Olivier, Bardwell, Vivian J., Melnick, Ari M.

“…The EZH2 histone methyltransferase mediates the humoral immune response and drives lymphomagenesis through formation of bivalent chromatin domains at critical…”
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Sexual cell-fate reprogramming in the ovary by DMRT1 by Lindeman, Robin E, Gearhart, Micah D, Minkina, Anna, Krentz, Anthony D, Bardwell, Vivian J, Zarkower, David

“…Transcription factors related to the insect sex-determination gene doublesex (DMRT proteins) control sex determination and/or sexual differentiation in diverse…”
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Gas-phase Ortho-to-para Ratio of Formaldehyde Formed at Low Temperatures in Laboratory Ices by Yocum, K. M., Wilkins, O. H., Bardwell, J. C., Milam, S. N., Gerakines, P. A.

“…The ortho-to-para ratio (OPR) of formaldehyde (H 2 CO) has been used as a probe to estimate the formation temperature of molecules in interstellar,…”
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The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming by Lindeman, Robin E, Murphy, Mark W, Agrimson, Kellie S, Gewiss, Rachel L, Bardwell, Vivian J, Gearhart, Micah D, Zarkower, David

“…Abstract Mammalian sexual development commences when fetal bipotential progenitor cells adopt male Sertoli (in XY) or female granulosa (in XX) gonadal cell…”
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Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome by Tara, Shiro, Isshiki, Yusuke, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Aoyama, Kazumasa, Tanaka, Tomoyuki, Shinoda, Daisuke, Koide, Shuhei, Saraya, Atsunori, Miyagi, Satoru, Manabe, Ichiro, Matsui, Hirotaka, Koseki, Haruhiko, Bardwell, Vivian J., Iwama, Atsushi

“…BCOR, encoding BCL-6 corepressor (BCOR), is X-linked and targeted by somatic mutations in various hematological malignancies including myelodysplastic syndrome…”
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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis by Kelly, Madison J., So, Joan, Rogers, Amy J., Gregory, Gareth, Li, Jason, Zethoven, Magnus, Gearhart, Micah D., Bardwell, Vivian J., Johnstone, Ricky W., Vervoort, Stephin J., Kats, Lev M.

“…The BCL6 Corepressor (BCOR) is a component of a variant Polycomb repressive complex 1 (PRC1) that is essential for normal development. Recurrent mutations in…”
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A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs by Wang, Zheng, Gearhart, Micah D., Lee, Yu-Wei, Kumar, Ishan, Ramazanov, Bulat, Zhang, Yan, Hernandez, Charles, Lu, Alice Y., Neuenkirchen, Nils, Deng, Jingjing, Jin, Jiaqi, Kluger, Yuval, Neubert, Thomas A., Bardwell, Vivian J., Ivanova, Natalia B.

“…Polycomb group proteins regulate self-renewal and differentiation in many stem cell systems. When assembled into two canonical complexes, PRC1 and PRC2, they…”
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An ancient protein-DNA interaction underlying metazoan sex determination by Murphy, Mark W, Lee, John K, Rojo, Sandra, Gearhart, Micah D, Kurahashi, Kayo, Banerjee, Surajit, Loeuille, Guy-André, Bashamboo, Anu, McElreavey, Kenneth, Zarkower, David, Aihara, Hideki, Bardwell, Vivian J

“…DMRT transcription factors, key regulators of metazoan sexual development, use a unique DNA binding mode critical for male-to-female sex reversal in humans…”
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A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters by Hatzi, Katerina, Jiang, Yanwen, Huang, Chuanxin, Garrett-Bakelman, Francine, Gearhart, Micah D., Giannopoulou, Eugenia G., Zumbo, Paul, Kirouac, Kevin, Bhaskara, Srividya, Polo, Jose M., Kormaksson, Matthias, MacKerell, Alexander D., Xue, Fengtian, Mason, Christopher E., Hiebert, Scott W., Prive, Gilbert G., Cerchietti, Leandro, Bardwell, Vivian J., Elemento, Olivier, Melnick, Ari

“…The BCL6 transcriptional repressor is required for the development of germinal center (GC) B cells and diffuse large B cell lymphomas (DLBCLs). Although BCL6…”
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The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis by Zhang, Teng, Murphy, Mark W, Gearhart, Micah D, Bardwell, Vivian J, Zarkower, David

“…In mammals, a key transition in spermatogenesis is the exit from spermatogonial differentiation and mitotic proliferation and the entry into spermatocyte…”
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Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation by Kim, Shinseog, Bardwell, Vivian J., Zarkower, David

“…Genes containing the DM domain, a conserved DNA binding motif first found in Doublesex of Drosophila and mab-3 of Caenorhabditis elegans, regulate sexual…”
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Modeling and measurement of lead tip heating and resonant length for implanted, insulated wires by Bardwell Speltz, Lydia J., Lee, Seung‐Kyun, Shu, Yunhong, Tarasek, Matthew R., Trzasko, Joshua D., Foo, Thomas K. F., Bernstein, Matt A.

“…Purpose To study implant lead tip heating because of the RF power deposition by developing mathematical models and comparing them with measurements acquired at…”
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Polycomb Group and SCF Ubiquitin Ligases Are Found in a Novel BCOR Complex That Is Recruited to BCL6 Targets by Gearhart, Micah D., Corcoran, Connie M., Wamstad, Joseph A., Bardwell, Vivian J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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KDM2B Recruitment of the Polycomb Group Complex, PRC1.1, Requires Cooperation between PCGF1 and BCORL1 by Wong, Sarah J., Gearhart, Micah D., Taylor, Alexander B., Nanyes, David R., Ha, Daniel J., Robinson, Angela K., Artigas, Jason A., Lee, Oliver J., Demeler, Borries, Hart, P. John, Bardwell, Vivian J., Kim, Chongwoo A.

“…KDM2B recruits H2A-ubiquitinating activity of a non-canonical Polycomb Repression Complex 1 (PRC1.1) to CpG islands, facilitating gene repression. We…”
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OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR by Hamline, Michelle Y., Corcoran, Connie M., Wamstad, Joseph A., Miletich, Isabelle, Feng, Jifan, Lohr, Jamie L., Hemberger, Myriam, Sharpe, Paul T., Gearhart, Micah D., Bardwell, Vivian J.

“…BCOR is a critical regulator of human development. Heterozygous mutations of BCOR in females cause the X-linked developmental disorder Oculofaciocardiodental…”
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BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors by Kotov, Jessica A, Kotov, Dmitri I, Linehan, Jonathan L, Bardwell, Vivian J, Gearhart, Micah D, Jenkins, Marc K

“…CD4 T helper 17 (Th17) cells protect vertebrate hosts from extracellular pathogens at mucosal surfaces. Th17 cells form from naive precursors when signals from…”
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DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary by Krentz, Anthony D., Murphy, Mark W., Sarver, Aaron L., Griswold, Michael D., Bardwell, Vivian J., Zarkower, David

“…Dmrt1 belongs to the DM domain gene family of conserved sexual regulators. In the mouse Dmrt1 is expressed in the genital ridge (the gonadal primordium) in…”
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