Search Results - "Bardot, B"

Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity by Bardot, B, Bouarich-Bourimi, R, Leemput, J, Lejour, V, Hamon, A, Plancke, L, Jochemsen, A G, Simeonova, I, Fang, M, Toledo, F

“…Mdm4, a protein related to the ubiquitin-ligase Mdm2, is an essential inhibitor of tumor suppressor protein p53. In both human and mouse cells, the Mdm4 gene…”
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Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival by Fang, M, Simeonova, I, Bardot, B, Lejour, V, Jaber, S, Bouarich-Bourimi, R, Morin, A, Toledo, F

“…The p53 pathway is inactivated in most human cancers, and its reactivation in tumors appears as a promising therapeutic strategy. Overexpression of Mdm4, a p53…”
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Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival by Fang, M, Simeonova, I., Bardot, B., Lejour, V., Jaber, S., Bouarich-Bourimi, R., Morin, A., Toledo, Franck

“…The p53 pathway is inactivated in most human cancers, and its reactivation in tumors appears as a promising therapeutic strategy. Overexpression of Mdm4, a p53…”
Get full text

Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity by Bardot, B, Bouarich-Bourimi, R, Leemput, J, Lejour, V, Hamon, A, Plancke, L, Jochemsen, A, Simeonova, I, Fang, M, Toledo, F

“…Mdm4, a protein related to the ubiquitin-ligase Mdm2, is an essential inhibitor of tumor suppressor protein p53. In both human and mouse cells, the Mdm4 gene…”
Get full text

Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival by Fang, M, Simeonova, I, Bardot, B, Lejour, V, Jaber, S, Bouarich-Bourimi, R, Morin, A, Toledo, Franck

“…The p53 pathway is inactivated in most human cancers, and its reactivation in tumors appears as a promising therapeutic strategy. Overexpression of Mdm4, a p53…”
Get full text

adhesion force of Notch with Delta and the rate of Notch signaling by Ahimou, Francois, Mok, Lee-Peng, Bardot, Boris, Wesley, Cedric

“…Notch signaling is repeatedly used during animal development to specify cell fates. Using atomic force microscopy on live cells, chemical inhibitors, and…”
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Biosynthesis, Post-translation Modification, and Functional Characterization of Drm/Gremlin by Topol, Lilia Z., Bardot, Boris, Zhang, Qingyun, Resau, James, Huillard, Emmanuelle, Marx, Maria, Calothy, Georges, Blair, Donald G.

“…Down-regulated bymos (Drm)/Gremlin is a highly conserved protein whose properties and expression pattern suggest a role in early development, tissue-specific…”
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The Notch amino terminus regulates protein levels and Delta-induced clustering of Drosophila Notch receptors by Bardot, Boris, Mok, Lee-Peng, Thayer, Tristan, Ahimou, Francois, Wesley, Cedric

“…Notch signaling is required for the development of almost all animal tissues. It is a cell surface receptor that generates intracellular signals in response to…”
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Enhanced tumor development in mice lacking a functional type I interferon receptor by Picaud, Sandrine, Bardot, Boris, De Maeyer, Edward, Seif, Isabelle

“…The aim of this study was to investigate the contribution of endogenous - that is, without the addition of any interferon (IFN) inducer - type I IFN production…”
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Drm/Gremlin, a BMP antagonist, defines the interbud region during feather development by Bardot, Boris, Lecoin, Laure, Fliniaux, Ingrid, Huillard, Emmanuelle, Marx, Maria, Viallet, Jean P

“…The pattern of feather buds in a tract is thought to result from the relative ratios between activator and inhibitor signals through a lateral inhibition…”
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Delta activity independent of its activity as a ligand of Notch by Mok, Lee-Peng, Qin, Tielin, Bardot, Boris, LeComte, Matthew, Homayouni, Asal, Ahimou, Francois, Wesley, Cedric

“…Delta, Notch, and Scabrous often function together to make different cell types and refine tissue patterns during Drosophila development. Delta is known as the…”
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Expression pattern of the drm/gremlin gene during chicken embryonic development by Bardot, Boris, Lecoin, Laure, Huillard, Emmanuelle, Calothy, Georges, Marx, Maria

“…The drm gene encodes a cystine knot-containing secreted and cell membrane-associated glycoprotein shown to be an antagonist of BMPs. Drm was recently reported…”
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