Search Results - "Bardia, Lidia"
-
1
Neurogenesis redirects β-catenin from adherens junctions to the nucleus to promote axonal growth
Published in Development (Cambridge) (15-08-2023)“…Here, we show that, in the developing spinal cord, after the early Wnt-mediated Tcf transcription activation that confers dorsal identity to neural stem cells,…”
Get full text
Journal Article -
2
Targeted immunotherapy against distinct cancer-associated fibroblasts overcomes treatment resistance in refractory HER2+ breast tumors
Published in Nature communications (09-09-2022)“…About 50% of human epidermal growth factor receptor 2 (HER2)+ breast cancer patients do not benefit from HER2-targeted therapy and almost 20% of them relapse…”
Get full text
Journal Article -
3
Urease-powered nanobots for radionuclide bladder cancer therapy
Published in Nature nanotechnology (01-04-2024)“…Bladder cancer treatment via intravesical drug administration achieves reasonable survival rates but suffers from low therapeutic efficacy. To address the…”
Get full text
Journal Article -
4
Rational optimization of a transcription factor activation domain inhibitor
Published in Nature structural & molecular biology (01-12-2023)“…Transcription factors are among the most attractive therapeutic targets but are considered largely ‘undruggable’ in part due to the intrinsically disordered…”
Get full text
Journal Article -
5
Transient and DNA‐free in vivo CRISPR/Cas9 genome editing for flexible modeling of endometrial carcinogenesis
Published in Cancer communications (London, England) (01-05-2023)“…Abbreviations CRISPR Clustered Regularly Interspaced Short Palindromic Repeats crRNA CRISPR RNA PTEN Phosphatase and Tensin homolog EC Endometrial Carcinoma…”
Get full text
Journal Article -
6
LOBSTER: an environment to design bioimage analysis workflows for large and complex fluorescence microscopy data
Published in Bioinformatics (15-04-2020)“…Abstract Summary Open source software such as ImageJ and CellProfiler greatly simplified the quantitative analysis of microscopy images but their applicability…”
Get full text
Journal Article -
7
Reversible silencing of endogenous receptors in intact brain tissue using 2-photon pharmacology
Published in Proceedings of the National Academy of Sciences - PNAS (02-07-2019)“…The physiological activity of proteins is often studied with loss-of-function genetic approaches, but the corresponding phenotypes develop slowly and can be…”
Get full text
Journal Article -
8
MosaicExplorerJ: Interactive stitching of terabyte-size tiled datasets from lightsheet microscopy [version 2; peer review: 2 approved]
Published in F1000 research (2021)“…We introduce MosaicExplorerJ, an ImageJ macro to stitch 3D tiles from terabyte-size microscopy datasets organized on a regular 2D grid. As opposed to existing…”
Get full text
Journal Article -
9
AutoScanJ: A Suite of ImageJ Scripts for Intelligent Microscopy
Published in Frontiers in bioinformatics (18-03-2021)“…We developed AutoscanJ, a suite of ImageJ scripts enabling to image targets of interest by automatically driving a motorized microscope at the corresponding…”
Get full text
Journal Article -
10
Metastatic recurrence in colorectal cancer arises from residual EMP1+ cells
Published in Nature (London) (17-11-2022)“…Around 30–40% of patients with colorectal cancer (CRC) undergoing curative resection of the primary tumour will develop metastases in the subsequent years 1 …”
Get full text
Journal Article -
11
Neurogenesis changes β-catenin shipping address from adherens junctions to nucleus to booster axonal growth
Published in Development (Cambridge) (31-07-2023)“…Here we show that in the developing spinal cord (SC), after the early Wnt-mediated Tcf-transcription activation that confers dorsal identity to neural stem…”
Get full text
Journal Article -
12
MosaicExplorerJ: Interactive stitching of terabyte-size tiled datasets from lightsheet microscopy [version 1; peer review: 2 approved with reservations]
Published in F1000 research (2020)“…We introduce MosaicExplorerJ, an ImageJ macro to stitch 3D tiles from terabyte-size microscopy datasets. As opposed to existing software, stitching does not…”
Get full text
Journal Article -
13
Short-term effects and teratogenicity of heptanol on embryos of Xenopus laevis
Published in Environmental toxicology and pharmacology (2004)“…This study examined teratogenic and short-term effects of heptanol on Xenopus embryos. Embryos were exposed for 5 h to 2.5 mM heptanol at different…”
Get full text
Journal Article