Search Results - "Barderas, Rodrigo"

Recombinant antibodies and their use for food immunoanalysis by Peltomaa, Riikka, Barderas, Rodrigo, Benito-Peña, Elena, Moreno-Bondi, María C.

“…Antibodies are widely employed as biorecognition elements for the detection of a plethora of compounds including food and environmental contaminants,…”
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Disposable immunoplatforms for the simultaneous determination of biomarkers for neurodegenerative disorders using poly(amidoamine) dendrimer/gold nanoparticle nanocomposite by Serafín, Verónica, Razzino, Claudia A., Gamella, Maria, Pedrero, María, Povedano, Eloy, Montero-Calle, Ana, Barderas, Rodrigo, Calero, Miguel, Lobo, Anderson O., Yáñez-Sedeño, Paloma, Campuzano, Susana, Pingarrón, José M.

“…Early diagnosis in primary care settings can increase access to therapies and their efficiency as well as reduce health care costs. In this context, we report…”
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Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer by TORRES, Sofia, BARTOLOME, Rubén A, BONILLA, Felix, IGNACIO CASAL, J, MENDES, Marta, BARDERAS, Rodrigo, FERNANDEZ-ACENERO, M. Jesus, PELAEZ-GARCIA, Alberto, PENA, Cristina, LOPEZ-LUCENDO, María, VILLAR-VAZQUEZ, Roi, GARCIA DE HERREROS, Antonio

“…Cancer-associated fibroblasts (CAF) are essential components of the stroma that play a critical role in cancer progression. This study aimed to identify novel…”
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A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells by Muñoz-San Martín, Cristina, Pedrero, María, Gamella, Maria, Montero-Calle, Ana, Barderas, Rodrigo, Campuzano, Susana, Pingarrón, José M.

“…Proteases are involved in cancer‚ taking part in immune (dis)regulation, malignant progression and tumour growth. Recently, it has been found that expression…”
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Autoantibodies in cancer: a systematic review of their clinical role in the most prevalent cancers by Montero-Calle, Ana, Garranzo-Asensio, María, Moreno-Casbas, Maria Teresa, Campuzano, Susana, Barderas, Rodrigo

“…Although blood autoantibodies were initially associated with autoimmune diseases, multiple evidence have been accumulated showing their presence in many types…”
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Anticipating metastasis through electrochemical immunosensing of tumor hypoxia biomarkers by Muñoz-San Martín, Cristina, Gamella, Maria, Pedrero, María, Montero-Calle, Ana, Pérez-Ginés, Víctor, Camps, Jordi, Arenas, Meritxell, Barderas, Rodrigo, Pingarrón, José M., Campuzano, Susana

“…Metastasis is responsible for about 90% of cancer-associated deaths. In the context of solid tumors, the low oxygen concentration in the tumor microenvironment…”
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The Molecular Misreading of APP and UBB Induces a Humoral Immune Response in Alzheimer’s Disease Patients with Diagnostic Ability by Montero-Calle, Ana, San Segundo-Acosta, Pablo, Garranzo-Asensio, María, Rábano, Alberto, Barderas, Rodrigo

“…Alzheimer’s disease (AD) is the most common cause of dementia worldwide with 10–30% prevalence in aging population and a high socioeconomic impact. Because AD…”
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Phage Display in the Quest for New Selective Recognition Elements for Biosensors by Peltomaa, Riikka, Benito-Peña, Elena, Barderas, Rodrigo, Moreno-Bondi, María C

“…Phages are bacterial viruses that have gained a significant role in biotechnology owing to their widely studied biology and many advantageous characteristics…”
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In-depth Characterization of the Secretome of Colorectal Cancer Metastatic Cells Identifies Key Proteins in Cell Adhesion, Migration, and Invasion by Barderas, Rodrigo, Mendes, Marta, Torres, Sofia, Bartolomé, Rubén A., López-Lucendo, María, Villar-Vázquez, Roi, Peláez-García, Alberto, Fuente, Eduardo, Bonilla, Félix, Casal, J. Ignacio

“…Liver metastasis in colorectal cancer is the major cause of cancer-related deaths. To identify and characterize proteins associated with colon cancer…”
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Affinity maturation of antibodies assisted by in silico modeling by Barderas, Rodrigo, Desmet, Johan, Timmerman, Peter, Meloen, Rob, Casal, J. Ignacio

“…Rational engineering methods can be applied with reasonable success to optimize physicochemical characteristics of proteins, in particular, antibodies. Here,…”
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Binary MoS2 nanostructures as nanocarriers for amplification in multiplexed electrochemical immunosensing: simultaneous determination of B cell activation factor and proliferation-induced signal immunity-related cytokines by Arévalo, Beatriz, Blázquez-García, Marina, Valverde, Alejandro, Serafín, Verónica, Montero-Calle, Ana, Solís-Fernández, Guillermo, Barderas, Rodrigo, Campuzano, Susana, Yáñez-Sedeño, Paloma, Pingarrón, José M.

“…A dual immunosensor is reported for the simultaneous determination of two important immunity-related cytokines: BAFF (B cell activation factor) and APRIL (a…”
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Proteomics Analyses of Small Extracellular Vesicles of Aqueous Humor: Identification and Validation of GAS6 and SPP1 as Glaucoma Markers by Rejas-González, Raquel, Montero-Calle, Ana, Valverde, Alejandro, Salvador, Natalia Pastora, Carballés, María José Crespo, Ausín-González, Emma, Sánchez-Naves, Juan, Campuzano, Susana, Barderas, Rodrigo, Guzman-Aranguez, Ana

“…Cataracts and glaucoma account for a high percentage of vision loss and blindness worldwide. Small extracellular vesicles (sEVs) are released into different…”
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Contributing to the management of viral infections through simple immunosensing of the arachidonic acid serum level by Torrente-Rodríguez, Rebeca M., Ruiz-Valdepeñas Montiel, Víctor, Iftimie, Simona, Montero-Calle, Ana, Pingarrón, José M., Castro, Antoni, Camps, Jordi, Barderas, Rodrigo, Campuzano, Susana, Joven, Jorge

“…A trendsetting direct competitive-based biosensing tool has been developed and implemented for the determination of the polyunsaturated fatty acid arachidonic…”
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In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer patients with low C1GALT1 expression by Montero-Calle, Ana, López-Janeiro, Álvaro, Mendes, Marta L., Perez-Hernandez, Daniel, Echevarría, Irene, Ruz-Caracuel, Ignacio, Heredia-Soto, Victoria, Mendiola, Marta, Hardisson, David, Argüeso, Pablo, Peláez-García, Alberto, Guzman-Aranguez, Ana, Barderas, Rodrigo

“…Background Endometrial cancer (EC) is the most common cancer of the female reproductive organs. Despite the good overall prognosis of most low-grade ECs, FIGO…”
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Identification of Tumor-associated Autoantigens for the Diagnosis of Colorectal Cancer in Serum Using High Density Protein Microarrays by Babel, Ingrid, Barderas, Rodrigo, Díaz-Uriarte, Ramón, Martínez-Torrecuadrada, Jorge Luis, Sánchez-Carbayo, Marta, Casal, J. Ignacio

“…There is a mounting evidence of the existence of autoantibodies associated to cancer progression. Antibodies are the target of choice for serum screening…”
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Bioluminescent detection of zearalenone using recombinant peptidomimetic Gaussia luciferase fusion protein by Peltomaa, Riikka, Fikacek, Sabrina, Benito-Peña, Elena, Barderas, Rodrigo, Head, Trajen, Deo, Sapna, Daunert, Sylvia, Moreno-Bondi, María C.

“…The development of a bioluminescent immunosensor is reported for the determination of zearalenone (ZEA) based on a peptide mimetic identified by phage display…”
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Unraveling the nexus of oxidative stress, ocular diseases, and small extracellular vesicles to identify novel glaucoma biomarkers through in-depth proteomics by Rejas-González, Raquel, Montero-Calle, Ana, Pastora Salvador, Natalia, Crespo Carballés, María José, Ausín-González, Emma, Sánchez-Naves, Juan, Pardo Calderón, Sara, Barderas, Rodrigo, Guzman-Aranguez, Ana

“…Chronic ocular pathologies such as cataracts and glaucoma are emerging as an important problem for public health due to the changes in lifestyle and longevity…”
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Metabolic Reprogramming Helps to Define Different Metastatic Tropisms in Colorectal Cancer by Montero-Calle, Ana, Gómez de Cedrón, Marta, Quijada-Freire, Adriana, Solís-Fernández, Guillermo, López-Alonso, Victoria, Espinosa-Salinas, Isabel, Peláez-García, Alberto, Fernández-Aceñero, María Jesús, Ramírez de Molina, Ana, Barderas, Rodrigo

“…Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases, with the most frequent target organs being the liver and lung. Metabolic…”
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Development of a novel multiplex beads-based assay for autoantibody detection for colorectal cancer diagnosis by Villar-Vázquez, Roi, Padilla, Guillermo, Fernández-Aceñero, María Jesús, Suárez, Adolfo, Fuente, Eduardo, Pastor, Carlos, Calero, Miguel, Barderas, Rodrigo, Casal, J. Ignacio

“…Humoral response in cancer patients can be used for early cancer detection. By screening high‐density protein microarrays with sera from colorectal cancer…”
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In‐depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer by Garranzo‐Asensio, María, Rodríguez‐Cobos, Javier, San Millán, Coral, Poves, Carmen, Fernández‐Aceñero, María Jesús, Pastor‐Morate, Daniel, Viñal, David, Montero‐Calle, Ana, Solís‐Fernández, Guillermo, Ceron, María‐Ángeles, Gámez‐Chiachio, Manuel, Rodríguez, Nuria, Guzmán‐Aránguez, Ana, Barderas, Rodrigo, Domínguez, Gemma

“…Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the…”
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